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Drug Discovery and Development Centre

@h3dcentre.bsky.social

H3D is Africa’s first integrated holistic drug discovery and development centre. The Centre was founded at the University of Cape Town in April 2010 and pioneers world-class drug discovery in Africa.

8 Followers  |  19 Following  |  9 Posts  |  Joined: 20.05.2025  |  1.7431

Latest posts by h3dcentre.bsky.social on Bluesky

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⏰ Final call to register!

Join us for the H3D Open Day 🧪
📅 Sat, 1 Nov | 🕙 10:00–14:00 | 📍UCT

Tour our labs, meet scientists & explore study paths in drug discovery.

🔗 Sign up now: forms.gle/vBbnfnAQFxcp...

#H3D #OpenDay #DrugDiscovery #UCT #FinalCall

30.10.2025 10:18 — 👍 0    🔁 0    💬 0    📌 0
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🎉 Congratulations to Prof Kelly Chibale, Director of on your official induction as an International Member of the US National Academy of Medicine (NAM)!

A proud moment for African-led science 🌍 recognising your leadership in advancing drug discovery & global health innovation👏

30.10.2025 10:16 — 👍 1    🔁 0    💬 0    📌 0
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Artificial intelligence coupled to pharmacometrics modelling to tailor malaria and tuberculosis treatment in Africa - Nature Communications Authors analyzed malaria and tuberculosis drugs to create a pharmacometric model. They used an AI pipeline that prioritized pharmacogenetic drug-gene pairs with an emphasis on high variant frequency g...

Africa's genetic diversity challenges effective drug treatments 💊 In #NatCommun, Turon and Mulubwa et al. present an AI-driven pipeline coupled to pharmacometrics to identify key drug-gene pairs and optimise doses for African populations, focusing on malaria and TB: www.nature.com/articles/s41...

21.10.2025 07:47 — 👍 0    🔁 0    💬 0    📌 0
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🔬 Ever wondered how new medicines are discovered?

Join us for the H3D Open Day 2025 at UCT!

👩‍🔬 Tour our labs
💡 Meet our scientists
🚀 Explore careers in drug discovery

📅 1 Nov 2025 | 🕙 10:00–14:00
📍 IDM, UCT

👉 Register: bit.ly/4nHd77W

#H3D #OpenDay #DrugDiscovery #ScienceCareers #UCT

16.10.2025 10:18 — 👍 0    🔁 0    💬 0    📌 0
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Edward Odoi from the University of Ghana spent time at H3D, UCT (15 Sept–3 Oct 2025) to enhance his LC-MS skills and explore DMPK workflows. His first international trip was both inspiring and unforgettable! 🌍🔬 #H3D #ResearchExchange #DrugDiscovery #CapacityBuilding

13.10.2025 12:52 — 👍 0    🔁 0    💬 0    📌 0
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Optimization of 2,8-Diaryl-1,5-naphthyridines as Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors with Improved ADME Profiles and In Vivo Efficacy Previously reported antimalarial Plasmodium phosphatidylinositol 4-kinase IIIβ 2,8-diaryl-1,5-naphthyridine inhibitors have shown suboptimal physicochemical and pharmacokinetic properties. A focused t...

📢 Just out in #JMedChem! Dziwornu et al. describe the optimization of 2,8-diaryl-1,5-naphthyridines as #Plasmodium falciparum phosphatidylinositol 4‑kinase (PI4K) inhibitors with improved ADME profiles and in vivo efficacy 🐭 #malaria pubs.acs.org/doi/10.1021/...

10.10.2025 13:34 — 👍 0    🔁 0    💬 0    📌 0
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Join @h3dfoundation.bsky.social for the webinar series

📅 Thursday, 16 October 2025
⌚ 12PM (SAST)
👨🏽‍🔬 Kirandeep Kaur Samby Johnson & Johnson
💡 Screening Smarter: How Library Design Drives Discovery

Register and join here: lnkd.in/d8vWEGfg

10.10.2025 12:08 — 👍 0    🔁 0    💬 0    📌 0
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Join @h3dfoundation.bsky.social for the webinar series

📅 Monday, 13 October
⌚ 12PM (SAST)
👨🏽‍🔬 Dr James Duffy Medicines for Malaria Venture
💡 The use of free drug concepts to guide compound optimisation in antimalarial drug discovery projects

Register and join here: lnkd.in/des-CzDB

10.10.2025 12:01 — 👍 0    🔁 0    💬 0    📌 0
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From pharmacist to lab-based drug discovery scientist In celebration of FIP World Pharmacist Day* (25 September) last week, we asked Dr Mathew Njoroge, chief investigator in the H3D Drug Metabolism and Pharmacokinetics (DMPK) team to share some insights ...

Celebrating #WorldPharmacistDay on the 25th of September 💊✨

From clinic to lab, Chief Investigator Mathew Njoroge shares his journey into #drugdiscovery, showing how pharmacists can shape new therapies & strengthen Africa’s research ecosystem🌍🧪

🔗 Read the full article here: lnkd.in/dtRi_xXd

01.10.2025 09:06 — 👍 0    🔁 0    💬 0    📌 0
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Introducing @h3dcentre.bsky.social! Focused on infectious diseases, they advance platforms and training to improve treatment across Africa. Through RAFIKI, H3D leads efforts to build compound- and data-sharing infrastructure for African drug discovery. #RAFIKI #DrugDiscovery #HorizonEU

23.09.2025 11:46 — 👍 3    🔁 1    💬 0    📌 0

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