Swedish Medical Birth Register study of pregnancy in systemic sclerosis (SSc) shows increased risk of preeclampsia (RR 3.8; 1.8-7.8), preterm birth (3.3; 1.8-6.1), & caesareans (2.5; 1.8-3.5) esp w/ 1st pregnancy acrjournals.onlinelibrary.wiley.com/doi/10.1002/...
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Also great to see further reassuring data for anakinra in pregnancy, now out from France academic.oup.com/rheumatology...
14.07.2025 07:06 — 👍 1 🔁 1 💬 0 📌 0
ℹ️ Mise au point
Quelle place de la protéine ADAMTS13 recombinante humaine dans le traitement du purpura thrombotique thrombocytopénique ? Retrouvez les recommendations du CNR des microangiopathies thrombotiques sur les indications et modalités d’administration👇
www.sciencedirect.com/science/arti...
✨July Issue✨| Monogenic systemic vasculitis
In this Review, the authors discuss the pathogenesis, clinical presentations and treatment of monogenic systemic vasculitis.
Free to read: bit.ly/3I0cw14 🔓
#Rheumsky #Medsky
Le 90ème Congrès #SNFMI débute demain à #Vichy
snfmivichy2025.com
Découvrez d'ores et déjà l'ensemble des résumés de Communications dans notre Numéro spécial Congrès : www.sciencedirect.com/journal/la-r...
French protocol for diagnosis and management of type 1 interferonopathies
www.sciencedirect.com/science/arti...
Inflammatory response to UVB exposure in Trim21-/- mice
doi.org/10.1002/art....
Open-label trial of escalation to golimumab in early axSpA gut inflammation
doi.org/10.1002/art....
Our July issue is live!
Including research on patient-reported outcomes in #SLE, #SystemicSclerosis associated #ILD, autoimmune diseases during #pregnancy, and treatment outcomes in #VEXAS syndrome, plus much more! www.thelancet.com/journals/lan...
Cover by Sara Gironi Carnevale #Medsky #Rheumsky
The clinical responses in Patients 1 and 2 before and after the first dose of CM336 through 6 months.
Two patients had autoimmune hemolytic anemia that relapsed after CD19 CAR T-cell therapy but responded rapidly to BCMA-targeted T-cell–engager therapy with remission, minimal side effects, and hematologic improvement. Learn more: nej.md/3SM6S4V
#MedSky #Immunology
NEW RESEARCH—Exposure to #hydroxychloroquine in early #pregnancy and incidence of pre-eclampsia and pre-term delivery in patients with systemic #lupus erythematosus in Sweden: a nationwide population-based cohort study bit.ly/3FBPz3J @rheumepi.bsky.social
Plus, linked Comment bit.ly/3Tknh0D
NEW RESEARCH—Trends in the prevalence of autoimmune diseases during #pregnancy in the UK, 2000–21: a retrospective cohort study bit.ly/449fPe3 #Medsky #Rheumsky
Plus linked Comment by @hilarykbrown.bsky.social & @nataliescime.bsky.social bit.ly/3HrIPps
Late breaking at #ASCO25:
A 3-year structured exercise program after adjuvant chemotherapy for colon cancer improved disease-free and overall survival, physical functioning, and fitness, as compared with health education alone. Full CHALLENGE phase 3 trial: nej.md/4mh5RPL
@ascocancer.bsky.social
NEW RESEARCH for #LUPUS2025 —Maternal autoantibodies to the sodium potassium pump α1 subunit AT1A1 and fetal autoimmune congenital heart block: a case-control study bit.ly/43lRzol
Plus, linked Comment bit.ly/3STJLoV
#Medsky #Rheumsky
🖼️Portrait
Découvrez Alexandre Belot, PUPH en rhumatologie pédiatrique et co-coordinateur de la filière FAI2R, ainsi que son regard sur la médecine interne et son avenir.
www.sciencedirect.com/science/arti...
A Review in Nature Reviews Immunology provides an overview of the current vaccines that are offered during pregnancy and to newborns, explaining the rationale behind the different vaccination programmes and the unique challenges that come with immunizing these populations. 🔒
18.05.2025 13:50 — 👍 22 🔁 10 💬 0 📌 1🔬Du 12 au 17 mai, @ap-hp.bsky.social célèbre celles et ceux qui font avancer la recherche pour améliorer les soins et donner de l’espoir aux patients. #recherche #recherchemedicale #rhumatologie #spondyloarthritis #spondyloarthrite
12.05.2025 11:15 — 👍 6 🔁 3 💬 0 📌 0
🤔Missed any #RheumaPreg25 sessions?
No worries! Join the highlights webinar on May 26. Contact @karenschreiber.bsky.social or @lauraandreoli.bsky.social to join the #ReHFaP mailing list 📩
⚖️ Faut il traiter le lymphome du MALT dans la maladie de Sjögren?
✅Pour?
www.sciencedirect.com/science/arti...
🚫Contre?
www.sciencedirect.com/science/arti...
⚖️ Inauguration de la rubrique « Controverse » ce mois ci dans la Revue de Médecine Interne
www.sciencedirect.com/science/arti...
A schematic representation of clonal hematopoiesis of indeterminate potential (CHIP) and tumor-infiltrating clonal hematopoiesis (TI-CH) in a patient with lung cancer.
Both clonal hematopoiesis of indeterminate potential (CHIP) and cancer are more common with age. When they coexist in the same patient, CHIP cells may migrate to the tumor and have an adverse effect on overall survival. Full study results: nej.md/3EnzMVu
#MedSky #Hematology
Reducing the risk of all-cause dementia with intensive blood pressure control, the results of a cluster randomized trial in~34,000 participants. @naturemedicine.bsky.social
www.nature.com/articles/s41...
Time-dependent effect of prophylactic trimethoprim-sulfamethoxazole on the incidence of serious infections in ANCA-associated vasculitis: A target trial emulation study. Graphical abstract created with BioRender
Multicenter cohort trial emulation tested TMP-SMX prophylaxis on incidence of serious infections in pts w/ ANCA-associated vasculitis. TMP-SMX significantly reduced risk of serious infections, esp. during 1st 6 mo. of induction therapy w/ RTX or CYC
A&R
doi.org/10.1002/art....
#Medsky #Rheum #IDsky
The New England Journal of Medicine Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis A Research Summary based on Furie RA et al. | 10.1056/NEJMoa2410965 | Published on February 7, 2025 Visual representations of the patients in the trial and the treatments they were assigned. Read the full Research Summary at NEJM.org.
In the REGENCY phase 3 trial, obinutuzumab, a humanized type II anti-CD20 monoclonal antibody, plus standard therapy provided significantly better renal responses than standard therapy alone in patients with lupus nephritis. Full trial results and Research Summary: nej.md/3Eq6gxV
#MedSky
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Human papillomavirus et lupus systémique : une revue systématique
www.sciencedirect.com/science/arti...
#SLE #HPV
“Even though individuals might feel powerless, we all have our own spheres of influence” 🌐
A Comment in The Lancet on why and *how* academic medicine must champion diversity, equity, inclusion, and accessibility 👉 bit.ly/4cwIBZL
Here is our latest on treatments in lupus. We studied glucocorticoids (GC) and hydroxychloroquine (HCQ) trends over time in patients with lupus in Sweden 2005-2021. The treatment guidelines have changed over time and aim for more HCQ and less GC (lower doses). academic.oup.com/rheumatology...
14.04.2025 07:21 — 👍 6 🔁 3 💬 1 📌 0
Figure showing the endocrine organs affected by immune-related adverse events, with lists of the main effects.
In this Review from our May issue, Shintaro Iwama, Tomoko Kobayashi & Hiroshi Arima discuss the management, biomarkers and prognosis in people developing #endocrinopathies associated with #immune checkpoint inhibitors (£) go.nature.com/43TbTQ2 #EndoSky
14.04.2025 10:47 — 👍 3 🔁 2 💬 0 📌 0
