Thatβs my pension fund π
20.01.2026 15:50 β π 11 π 0 π¬ 0 π 0Thatβs my pension fund π
20.01.2026 15:50 β π 11 π 0 π¬ 0 π 0Amazing to hold @lottepedersen.bsky.social & my @jcellsci.bsky.social Special Issue on #Cilia and #Flagella in all its glossy glory & muscle-engaging brain-boosting weight! So much fabulous content from the community! Fab cover @centriolelab.bsky.social π₯°π₯° journals.biologists.com/jcs/pages/ci...
16.01.2026 19:30 β π 48 π 13 π¬ 2 π 0Woohoo I cannot wait to get the hard copy π€©
16.01.2026 20:10 β π 2 π 0 π¬ 0 π 0
π£ Seminar
π Thursday, January 22nd at 2 pm
π Institut Jacques Monod
Next week, Seema Grewal ( @seemagrewal.bsky.social) , Executive Editor at Journal of Cell Science ( @jcellsci.bsky.social ) will present the seminar "The Future of Publishing"
β‘οΈ buff.ly/j69lKP3
The EMBO Workshop "#Centrosomes: From fundamentals to diseases" in #Lausanne, Switzerland, 1β4 September 2026 will highlight the advances in the field of centrosome #research. Register now!
Deadline: 1 June
https://meetings.embo.org/event/26-centrosomes
#EMBOCentrosomes #EMBOevents #conference π§ͺ
We are back April 21 2026- volunteer or nominate yourself or someone with hot cilia and centrosome science to speak by dropping me an email or use the google doc forms.gle/9QoSvkmQ3gZL...! /FIN
13.01.2026 23:05 β π 6 π 4 π¬ 0 π 0From limitless primary basal cells for #PCD therapies, to the TOGORAM1 complex, cytoskeleton & ciliopathies, to #PrimaryCilia diversity in brain #microvasculature, to #ExtrasynapticSignaling at neuronal cilia by in situ proteomics, to an epigenetic 'eraser' controlling #cilia stability... π₯ /fin
05.01.2026 17:40 β π 8 π 3 π¬ 1 π 0
What a great start for 2026 for the EVICAT team!!!
Everything you need to know about extracellular vesicles' recipient cells and how to harness these pathways for therapeutic purposes
Thanks to all co-authors!
bit.ly/3N9InyW
Cilia2027, the 7th European Cilia Conference to be held in Italy from March 8th- 12th, 2027.
π Cilia2027 | Mar 8β12, 2027 | π Stresa, Lake Maggiore, Italy
Join the global cilia community for science, collaboration & discovery (+ fun!!).
#Cilia2027 #CiliaBiology
Top: lf5 mutant cells untransformed, or expressing CDKL5-GFP, CDKL5K33R-GFP, CDKL5S162A,T164A,Y166A-GFP, or CDKL5Y166F-GFP, and lf2 mutant cells expressing CDKL5-GFP were stained for flagella (acetylated tubulin, red) and CDKL5 (GFP, green top panels, gray in bottom panels). The cell bodies of all strains are green (or gray) due to autofluorescence. Wild-type CDKL5-GFP concentrates at the basal end of the flagellar shaft (arrows). Note that all of the mutant CDKL5 proteins lack the major enrichment at the basal end of the flagellum but continue to show punctate stain along the flagellar shaft. Scale bar, 5 Β΅m. Z projection of slices taken at 0.5-Β΅m intervals. Bottom: Larger version of the first image in the top row.
CDKL5 Deficiency Disorder (CDD) leads to seizures & intellectual disability. This study shows that #Chlamydomonas CDKL5 kinase is activated by the LF2/CDK20 kinase; CDKL5 in turn regulates #intraflagellar transport via protein abundance & phosphorylation #cilia @plosbiology.org π§ͺ plos.io/45490eP
15.12.2025 17:28 β π 5 π 3 π¬ 0 π 0Oh they are sooo cute π
16.12.2025 15:48 β π 1 π 0 π¬ 0 π 0
Very grateful to @carlsbergfondet.dk for supporting our Research Infrastructure application to purchase a new NTA for studying #cilia and #extracellular #vesicles ππ
bsky.app/profile/carl...
π₯³ Our new paper on C2CD3 is out in @plosbiology.org
With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET.
Big congrats to @ebertiaux.bsky.social and all involved.
Nice work indeed⦠among all the interesting findings, quite amazed to see that you can induce the formation of ciliary pockets just by the removal of Arp3! #cilia #ciliopathies #kidney
02.12.2025 13:11 β π 3 π 1 π¬ 0 π 0
Dynein-2 prefers to bind the retrograde-targeted A-tubule in intraflagellar transport - likely because of its tyrosination, suggest cryo-ET data and MD simulations by @ichikawa-lab.bsky.social and coworkers
www.embopress.org/doi/full/10....
Weβre excited for the UK Cilia and Centrosome Network e-symposium this afternoon featuring the #JCSciliaSI!
To discover more about the research in this issue, check out these JCS snapshots, video highlights from authors about their research: focalplane.biologists.com/2025/11/24/j...
And weβll be back for four sessions in 2026- first 14/01/2026! Register: www.eventbrite.co.uk/e/bscb-genso...
#UKCilia2025 /9
In the meantime, try a deep dive into our JCS Special Issue on Cilia and Flagella to fully immerse yourself into some great research, fantastic insight and provocative opinions: journals.biologists.com/jcs/issue/13... /fin
25.11.2025 19:27 β π 8 π 3 π¬ 0 π 0Thanks for the shoutout! @jcellsci.bsky.social :)
17.11.2025 19:04 β π 7 π 3 π¬ 0 π 0It was a lot of fun to write this review on cilia proteimics with Bernhard Schermer @cilib.social.cologne.ap.brid.gy and Ronald Ropeman, and we are excited to see it published in the @jcellsci.bsky.social special issue on Cilia and Flagella: from basic Biology to Disease.
04.11.2025 12:46 β π 12 π 3 π¬ 0 π 0Figure showing that tissue-resident macrophages promote cytogenesis in an in vitro 3D model system.
Rudolfo Karl, Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social and colleagues discover that renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease.
#JCSciliaSI
journals.biologists.com/jcs/article/...
Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase.
www.nature.com/articles/s41...
While trying to steer clear of the βbest organelleβ debate, weβre delighted to highlight #JCSciliaSI, guest edited by @cilialab.bsky.social & @lottepedersen.bsky.social.
And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!
Akisato Marumo, Hiroto Ishii, Shin Yamaguchi, Junichiro Yajima and colleagues characterise the 3D beating pattern of the ciliary tip in the live ciliate Tetrahymena.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#OpenAccess #ReadandPublish
Imaging Cell Dynamics 11-14 May 2026 MontanyΓ Hotel, Catalonia, Spain Register now - early-bird deadline: 16 January 2026 Journal of Cell Science Meeting
Registration is now open to attend Journal of Cell Science's meeting on Imaging Cell Dynamics, organised by Francesca Bottanelli, Guillaume Jacquemet, Michael Way and Giulia Zanetti.
Find out more: biologists.com/meetings/jcs...
#JCSimaging #Microscopy #Microscope #Imaging #Cells #CellScience
Figure showing that EP4 localizes to primary cilia of ASCs.
Mark Lee @guacamarklee.bsky.social and Keren Hilgendorf @uofubiochem.bsky.social discover that prostaglandin E2 inhibits adipogenesis through the cilia-dependent activation of ROCK2.
#JCSciliaSI
journals.biologists.com/jcs/article/...
π₯³TheRaCil Publications Alertπ¨Visit theracil.eu/news-and-pub... - cilia biology & perspectives for AI in nephrologyπKIF13B controls ciliary protein content, Rezi et al @lottepedersen.bsky.social πAI for diagnosis and care in rare kidney disease review, Chen et al @knebel.bsky.social #cilia #kidney
10.11.2025 14:03 β π 5 π 2 π¬ 0 π 0Figure showing that both overexpression of and loss of PPK-1 impacts shedding of CLHM-1-containing EVs.
Malek Elsayyid, Alexis Semmel, Jessica Tanis and colleagues find that phosphatidylinositol 4,5-bisphosphate impacts extracellular vesicle shedding from C. elegans ciliated sensory neurons.
#JCSciliaSI
journals.biologists.com/jcs/article/...
Keren Hilgendorf
Girish Ram Mali
Also in Issue 20:
- Editorial from Pleasantine Mill @cilialab.bsky.social and Lotte Pedersen @lottepedersen.bsky.social.
- 'Cell Scientist to Watch' interviews with Keren Hilgendorf and Girish Ram Mali @dyneinassembly.bsky.social
journals.biologists.com/jcs/issue/13...
#JCSciliaSI
Exciting news: the new review from @centriolelab.bsky.social is out in the amazing #JCSciliaSI! π
I had the pleasure of working alongside Olivier Mercey, Paul Guichard and Virginie Hamel on this one.
Cherry on top: our #UExM image was selected for the cover of the issue! π€©