Lenny Teytelman

Protocol.io logo

Last month, we highlighted Protocols.io as a new resource available at @bodleian.ox.ac.uk. Next week, as part OxFOS, you can sign up and join the Springer Nature team for a training session introducing the platform to researchers either in person here at the RSL or online

go.glam.ox.ac.uk/proto

Started this project years ago, but now everything is deposited on @addgene.bsky.social and a short @protocolsio.bsky.social is online. Try it out to make your own (cheap) homemade nuclease/Benzonase!

dx.doi.org/10.17504/protocols.io.261ged7xov47/v2

Thank you @jcoker10.bsky.social and Michael Lim!

We've updated our protocols.io page to highlight a couple of the protocols published by Crick authors recently.

If you're at the Crick, don't forget you can get your flat pdfs converted to the protocols.io format at no cost! 😀

www.protocols.io/organization...

a woman in a pink dress sits on a green pole on a stage ALT: a woman in a pink dress sits on a green pole on a stage

ONT seq help: Has anyone had success using less than the 10ng of input DNA for the 16S barcoding kit? Trying to use it for low biomass samples.

Given the recent #Nipah outbreak in India, here are two #Nanopore protocols for NiV genomic sequencing in support of rapid outbreak response:

IPC: www.protocols.io/view/sequenc...
icddr,b/CDC: journals.asm.org/doi/10.1128/...

Generation of Stickleback intestinal organoid Intestinal organoids offer significant advantages over conventional 2D cultures, providing a physiologically relevant 3D architecture that enables more realistic disease modelin...

New @protocolsio.bsky.social post describing our new protocol for generating intestinal organoids for #stickleback: www.protocols.io/view/generat...
With work by postdoc Arshad Padhiar, funded by @moorefound.bsky.social

Bring structure to your research - protocols.io A secure platform for developing and sharing reproducible methods.

Join Springer Nature editors and the protocols.io team for an exciting event as part of #LoveMethods26!
🔮Gain insight on methods publishing at our Methods Mythbusting on Jan 22. Our editor Sabrya Carim will be there!
👉FREE registration & more details:
www.protocols.io/blog/join-pr...

Join protocols.io and Springer Nature editors at Love Methods Week 2026 Love Methods Week 2026 will take place January 19-23, 2026 and is organized by University of Coimbra and the QUEST center. Online workshops focused on open and reproducible meth...

Join Springer Nature editors and the protocols.io team for two exciting events as part of #LoveMethods26!

💻Transform your protocols at our Hackathon on Jan 21

🔮Gain insight on methods publishing at our Methods Mythbusting on Jan 22

👉FREE registration & more details:

Sampling protocol for obtaining sediment from archaeological excavations in caves and rockshelters for the ... The objective of this protocol is to guide systematic collection of sediment samples from archaeological excavations in caves and rockshelters in order to perform biomolecular a...

You want to take sediment samples from archaeological sites for a variety of analysis?Have a look at our best practise sampling protocol:
www.protocols.io/view/samplin...

Join us for “Methods Mythbusting: Insights from Journal Editors and protocols.io”protocols.io/webinars/met...rs

at Love Methods Week 2026excelscior.uc.pt/love-methods...6/

#LoveMethods26

Some EBP-affiliates are embarking on ambitious R&D to tackle some of the hardest genomes on Earth. 🌍🧬

Great science starts with shared ideas — sometimes over coffee. 💥🤝☕️
Soak up the Sanger Tree of Life sponge protocol 👇
www.protocols.io/view/sanger-...

@seagrassliz.bsky.social #Biodiversity

A reliable in vitro rumen culture system and workflow for screening anti-methanogenic compounds Arguably the biggest man-made challenge of the century is halting climate change. Livestock’s methane (CH4) emissions, a greenhouse gas with a higher global warming potential than carbon dioxide…

A new Lab Protocol from @sabass-lab.bsky.social and colleagues presents an in vitro rumen culture and workflow that reproducibly screens anti-methanogenic compounds, aiding feed-based methane mitigation studies: plos.io/4oyyc4a

Protocol available via @protocolsio.bsky.social at plos.io/3KAOThi

Exciting news: Premium protocols.io is now available via Research4Life to researchers in low- & middle-income countries—at no or low cost.

🌟 Full Springer Nature press release: group.springernature.com/gp/group/med...

#OpenScience #Reproducibility #GlobalCollaboration #Research4Life #protocolsio

YouTube video by LIBRE hub Construyendo protocolos científicos reproducibles y abiertos con Protocols.io

It was great to hear from @lteytelman.bsky.social about Protocols.io today for our LIBRE hub channel on open science! We already have a tutorial in Spanish: youtu.be/RuBKWouEyL8?...

We have done our first @protocolsio.bsky.social. Are you interested about #genome_annotation quality evaluation? We have developed a tool called #GAQET2 (github.com/victorgcb198...) which runs several tools like #AGAT, #BUSCO, and many other tools. You can find it at www.protocols.io/view/structu...

LIBRE hub The Latin American Hub for Bioimaging Through Open Hardware (LIBRE_hub) is a training network for open source bioimaging hardware in Latin America with the goal to empower regional researchers through...

Appropriately, their share the resources, documentation, tutorials, seminars openly for everyone. Check out www.youtube.com/@librehub and librehub.github.io/sources/

The Latin American Hub for Bioimaging Through Open Hardware (LIBRE Hub) ...

Latin American Hub for Bioimaging Through Open Hardware (LIBRE Hub librehub.github.io) is an amazing initiative from @makertobey.bsky.social and colleagues!

With the full CRISPR 7-11 protocol here :)

CRISPR/Cas7-11 tool for RNA targeting in Xenopus laevis CRISPR/Cas systems are defense mechanisms in prokaryotic cells to induce the cleavage and degradation of nucleic acids derived from bacteriophages. Among the different classes,...

Link for the full CRISPR Cas7-11 protocol: www.protocols.io/view/crispr-...

Sox8 is essential for vertebrate gastrulation | EMBO reports imageimageThe use of CRISPR Cas7-11 uncovers a role for sox8 in Xenopus gastrulation as a regulator of Wnt signaling. sox8 downregulation in the ventrolateral mesoderm disrupts blastopore closure and...

Congratulations to @sofiram.bsky.social and @artemiskorovesi.bsky.social on our last paper about the role of Sox8 in #xenopus #gastrulation

A link to the whole paper is here www.embopress.org/doi/full/10....

Enabling options for review: from training and transparency to author-centered AI tools - openRxiv Peer review is widely viewed as a critical aspect of biomedical communication. Ideally, it provides authors with feedback so they can improve manuscripts and gives readers, particularly nonspecialists...

Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n

openrxiv.org/enabling-rev...

Optimisation of whole cell human depletion provides increased sensitivity and microbial genome coverage from respiratory metagenomic assays Metagenomics is being adopted worldwide as a laboratory developed test. We have previously reported a unified metagenomic method for the direct detection of microorganisms from respiratory samples, de...

Our new preprint covering the improvements we made to our respiratory metagenomic assay is out now:

www.medrxiv.org/content/10.1...

✅ Now implemented in 6 NHS hospitals
✅ Increased sensitivity
✅ Increased pathogen genome coverage

(1/3)

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

✨ Research assessment needs a rethink — and it finally feels like change might be possible.
At protocols.io (@protocolsio.bsky.social) and in my past life as a journal editor, I’ve had countless conversations about how we evaluate researchers. It’s a topic that keeps coming up — and for good reason.

Bring structure to your research - protocols.io A secure platform for developing and sharing reproducible methods.

Explore our new featured protocols protocols.io/welcome

Opinion | Can Trump End This Impossibly Cruel Practice?

In which I look at animal research for The New York Times and find some surprising answers.

Listening to #WhatTheRef podcast on the train en route to Birmingham for The Festival of Hidden Ref tomorrow and Weds, perfect listening material, thanks @hiddenref.bsky.social,
I'm giving a lightning talk on Thurs - very much looking forward to this event :)

Global Collaboration Made Easier: Multilingual Protocols Now Available on protocols.io Research is a global endeavour, yet the expectation to communicate in English often creates barriers and an additional burden for non-native speakers. At the lab bench or in t...

I've been dreaming about this for a decade and it's now live!

"Global Collaboration Made Easier: Multilingual Protocols Now Available on protocols.io"
www.protocols.io/blog/global-...

Copy our protocols!

📝 Find many of our lab protocols and techniques on @protocolsio.bsky.social at www.protocols.io/search?q=%22...

🎥 Go deeper with recorded video tutorials of some of our most requested methods: alleninstitute.org/education/sc...

#OpenScienceWeek

Plate CUT&Tag (Meers Lab version) This protocol describes a method for carrying out CUT&Tag-Direct in 96 well microplates for high-throughput processing of samples by a single operator with only standard lab...

We published a detailed protocol for our Plate-CUT&Tag method on @protocolsio.bsky.social to accompany our recent preprint (www.biorxiv.org/content/10.1...) give it a try! Feedback welcome! dx.doi.org/10.17504/protocols.io.n2bvjed5wgk5/v1