Annals of Internal Medicine

A new systematic review and meta-analysis of 20 randomized controlled trials shows #corticosteroids probably reduce short-term mortality in severe non-COVID-19 pneumonia & ARDS without raising infection risk. Read more at Annals.org: https://f.mtr.cool/wbqdfbszmg

NEW: Neighborhoods near #cannabis stores saw a 12% increase in cannabis-related ER visits compared to those farther away. The findings suggest that restrictions on the overall number of cannabis retail stores and store concentrations could offer #PublicHealth benefits. https://f.mtr.cool/droonbhkju

NEW: 1 in 8 men undergo scrotal surgery 20 years after kidney donation, underscoring the need for increased patient education about the risks and symptoms to monitor after donation. https://f.mtr.cool/xpxelntcyw

New from @acpimphysicians.bsky.social: Ethical organ transplantation must prioritize the donor patient’s best interests, and the process should be trustworthy and transparent. Read the position paper for free: bit.ly/4oyXoYs

Effectiveness of Recombinant Herpes Zoster Vaccine in the U.S. Medicare Population, 2018 to 2019, by Immunocompetence and Prior Receipt of Live Zoster Vaccine | Annals of Internal Medicine Background: Recombinant zoster vaccine (RZV) was preferentially recommended over live zoster vaccine (ZVL) starting in 2018. Objective: To assess RZV effectiveness using target trial emulation, accoun...

Researchers from UNC Chapel Hill found that the two-dose recombinant zoster vaccine (RZV) offered over 65% vaccine effectiveness against shingles, suggesting that those who previously received live zoster vaccine (ZVL) be revaccinated with RZV. bit.ly/46Rq5Kr

New study in @annalsofim.bsky.social shows rising rates of doctors leaving clinical practice across all specialties and regions.

🔗https://docit.ucsf.edu/news/new-research-reveals-rising-physician-attrition-puts-healthcare-workforce-risk

Although counties at the epicenter of the West Texas measles outbreak had high MMR vaccination rates, schools within those counties had lower rates, according to a new report. The findings underscore the importance of collecting granular vaccination data to mitigate disease outbreaks. bit.ly/48QpTfB

Online now: Leaders from @acpimphysicians.bsky.social warn of the effects of the politicalization of science and patient mistrust of the health care system. They caution that the health care system is vulnerable to future pandemics if these issues are not addressed. bit.ly/46FVeiA

Interview with Christine Laine The EIC of "Annals of Internal Medicine" discusses current events and more

Our interview with Christine Laine, Editor-in-Chief of @annalsofim.bsky.social where we namecheck @drandrealove.bsky.social discussing new insights about "the Tylenol paper," the importance of careful science claims, RFK Jr., AI in clinical medicine, and more.
www.the-geyser.com/interview-wi...

Hospital Staffing and Patient Outcomes After Private Equity Acquisition | Annals of Internal Medicine Background: After private equity acquisition, hospitals may experience changes in staffing with implications for patients. Objective: To examine hospital staffing and patient outcomes in emergency dep...

NEW: After #PrivateEquity acquisition, hospitals saw an increase in emergency department mortality and patient transfers to other hospitals. The researchers say this was likely caused by reduced staffing and salary expenditures. bit.ly/3VwkT8o

Blood-based multicancer detection (MCD) tests have emerged as a potentially transformative approach for cancer screening. The findings of a new systematic review assessing benefits, accuracy, and harms of MCD tests can inform focus areas for additional research. Read here: bit.ly/4n2Sz9x

Exposure to Computed Tomography Before Pregnancy and Risk for Pregnancy Loss and Congenital Anomalies: A Population-Based Cohort Study: Annals of Internal Medicine: Vol 0, No 0 Background: Animal studies show ovarian follicle damage and mutagenesis after ionizing radiation exposure. Computed tomography (CT) imaging is commonly done outside pregnancy, but risks to future preg...

An observational study of 5.1 million pregnancies and 3.4 million live births in Ontario, CA between 1992 and 2023 found that exposure to CT radiation before #pregnancy may be associated with higher risks for miscarriage and birth defects. bit.ly/3JNIKxL

NEW: A randomized controlled trial found that personalized risk messages to both patients and providers did not cause an uptake in screening for #colorectalcancer in patients with average risk. bit.ly/41DhXdn

Comparison of an Energy-Reduced Mediterranean Diet and Physical Activity Versus an Ad Libitum Mediterranean Diet in the Prevention of Type 2 Diabetes: A Secondary Analysis of a Randomized Controlled T... Background: Limited research has been done to evaluate the combined effect of energy reduction, Mediterranean diet (MedDiet), and physical activity on type 2 diabetes incidence. Objective: To evaluate...

Findings from a large, randomized trial suggest that adults who follow a #MediterraneanDiet, reduce their caloric intake, and regularly exercise can reduce their diabetes risk by 31%, compared to those who only follow a standard Mediterranean diet. bit.ly/47P7TBP

How can we reduce the risk of Type 2 diabetes by 31%
A randomized trial of the Mediterranean (MED) diet, weight loss (avg 7 lbs) and moderate exercise vs the MED diet alone
www.acpjournals.org/doi/full/10....

Editor in Chief Christine Laine, MD, MPH, recently sat down with the BBC Science in Action podcast to discuss the strengths and challenges of observational studies and reject calls to retract a study that found aluminum in vaccines does not increase health risks. Listen here: bbc.in/4lzVPIa

Engineering Infection Controls to Reduce Indoor Transmission of Respiratory Infections: A Scoping Review: Annals of Internal Medicine: Vol 0, No 0 Background: Engineering infection controls include a wide range of interventions used indoors to reduce occupants’ exposure to respiratory pathogens. Purpose: To identify and describe primary studies ...

🧵 THREAD (1/10)
🏢💨 How effective are engineering controls at stopping respiratory infections indoors? Our new scoping review in @annalsofim.bsky.social examined nearly 100 years of research to find out. The results reveal both promise and concerning gaps...
Link: www.acpjournals.org/doi/10.7326/...

Treatment With Canagliflozin Versus Placebo in Children and Adolescents With Type 2 Diabetes: A Randomized Clinical Trial: Annals of Internal Medicine: Vol 0, No 0 Background: Treatment options for children and adolescents with type 2 diabetes mellitus (T2DM) are limited. Canagliflozin is a sodium–glucose cotransporter-2 inhibitor approved for the treatment of T...

Researchers from Johnson & Johnson evaluated the safety and efficacy of canagliflozin in children and adolescents. The study found that canagliflozin provided a clinically meaningful reduction in HbA1c, with a safety profile similar to that seen in adults. Read the full text here: bit.ly/45rcxmX

People with social risk factors are at greater risk for long COVID, according to a new study. The findings suggest policy efforts are urgently needed to dismantle systemic drivers of social risk factors and to address health disparities exacerbated by the COVID-19 pandemic. bit.ly/4ohPgwu

A new editorial from ‪ACP President Jason Goldman, MD and Robert Hopkins, MD warns of the potential consequences on public confidence in vaccines following the recent dismantling and reconstitution of the Advisory Committee on Immunization Practices (ACIP). bit.ly/3TSLkUQ

Aluminum-Adsorbed Vaccines and Chronic Diseases in Childhood: A Nationwide Cohort Study: Annals of Internal Medicine: Vol 0, No 0 Background: Aluminum is used as an adjuvant in nonlive vaccines administered in early childhood. Concerns persist about potential associations between vaccination with aluminum-adsorbed vaccines and i...

A new study of over 1.2 million children found no association between aluminum in vaccines and an increased risk of chronic conditions including autism and asthma. The findings provide clear evidence of the safety of childhood vaccines. Read the full text for free at bit.ly/46LIZ5D

1 in 5 people who are overweight could be reclassified as living with obesity according to the new ‪EASO framework definition of obesity. The authors recommend for future studies to examine whether newly identified people with obesity would benefit from obesity treatment. bit.ly/4lL9tJr