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StressMarq Biosciences

@stressmarq.bsky.social

Dedicated to advancing the frontiers of neurodegenerative disease research. 🧠 Innovative product portfolio including pre-formed fibrils (PFFs), oligomers, & monomers for alpha synuclein, tau, & amyloid beta for use in disease modelling & drug discovery.

46 Followers  |  145 Following  |  128 Posts  |  Joined: 23.01.2025  |  1.651

Latest posts by stressmarq.bsky.social on Bluesky

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Human Tau (K18) Wild-Type PFFs (SPR-525) Order Human Tau (K18) Wild-Type PFFs (SPR-525) from StressMarq. High-quality reagents for neurodegenerative disease research.

New Product!⭐

StressMarq now offers Tau (K18) Wild-Type Pre-formed Fibrils. The Tau K18 fragment preserves the core pathogenic characteristics of full-length #tau while providing enhanced experimental control and reproducibility.

View the product details πŸ”Ž https://bit.ly/3LojZZF

21.11.2025 17:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Assessing Membrane Permeability in Neurodegeneration A novel high-throughput assay detects membrane damage at single-vesicle level, with exciting implications for Parkinson’s disease & drug discovery research.

A study @edinburgh-uni.bsky.social utilized StressMarq's #AlphaSynuclein A90C Mutant Monomers in the development of a high-throughput assay which detects membrane damage at the single-vesicle level.

Learn more about how these findings support #Parkinsons disease research πŸ’« https://bit.ly/3LGqqYi

20.11.2025 21:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Human Tau (K18) Wild-Type Monomers (SPR-524) Order Human Tau (K18) Wild-Type Monomers (SPR-524) from StressMarq. High-quality reagents for neurodegenerative disease research.

New Product!πŸ’‘

StressMarq now produces Tau (K18) Wild-Type Monomers, optimized for #tauopathy research. These monomers readily form fibrils when incubated with heparin or seeded with PFFs, enabling precise modeling of disease mechanisms.

View the product details πŸ”¬ https://bit.ly/3JHYGl8

20.11.2025 19:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Product Citation πŸ’

The APOE #Christchurch mutation shows selective #neuroprotective effects. StressMarq’s Mouse #AlphaSynuclein PFFs enabled an in vivo model to study the mutation’s impact on alpha synuclein and #tau pathologies.

Paper 🌸 https://bit.ly/43xksiy
Product 🌼 https://bit.ly/2HJyYee

20.11.2025 17:58 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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StressMarq will be exhibiting at #Neuroscience 2025 from November 16-19 in San Diego, CaliforniaπŸŒ…. Come by and visit Booth 822 to learn about our comprehensive portfolio of products for neuroscience research! #SfN2025 #neuroscience

Learn moreπŸ§ͺhttp://bit.ly/4qoGnSG

17.11.2025 00:23 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Human Tau (K18) Wild-Type PFFs (SPR-525) Order Human Tau (K18) Wild-Type PFFs (SPR-525) from StressMarq. High-quality reagents for neurodegenerative disease research.

New Product!⭐

StressMarq now offers Tau (K18) Wild-Type Pre-formed Fibrils. The Tau K18 fragment preserves the core pathogenic characteristics of full-length #tau while providing enhanced experimental control and reproducibility.

View the product details πŸ”Ž https://bit.ly/3LojZZF

14.11.2025 17:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Human Tau (K18) Wild-Type Monomers (SPR-524) Order Human Tau (K18) Wild-Type Monomers (SPR-524) from StressMarq. High-quality reagents for neurodegenerative disease research.

New Product!πŸ’‘

StressMarq now produces Tau (K18) Wild-Type Monomers, optimized for #tauopathy research. These monomers readily form fibrils when incubated with heparin or seeded with PFFs, enabling precise modeling of disease mechanisms.

View the product details πŸ”¬ https://bit.ly/3JHYGl8

13.11.2025 19:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Product Citation 🍎 StressMarq's #AlphaSynuclein Aggregate Antibody was employed by neuroscientists in China to evaluate the effects of chronic intermittent #hypoxia (CIH) on αSyn expression, neuronal function & cognitive ability.

Paper πŸ“• https://bit.ly/3JFbmcC
Product 🧧 https://bit.ly/3XfzwgR

13.11.2025 00:30 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Anti-NHE3 Antibody (SPC-400) - Rabbit Polyclonal Order Rabbit Anti-Rat NHE3 Polyclonal (SPC-400) from StressMarq. Suitable for WB, ICC/IF, IHC. High-quality antibodies for scientific research.

Product Citation πŸ’« Researchers at the University of SΓ£o Paulo employed StressMarq's #NHE3 Antibody to explore the role of NHE3 activity in acute kidney injury (AKI), and found that AKI is driven by inflammation and #apoptosis.

Paper 🌌 http://bit.ly/4nA63sV
Product 🌠 http://bit.ly/4nzr479

12.11.2025 14:16 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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StressMarq will be exhibiting at #Neuroscience 2025 from November 16-19 in San Diego, CaliforniaπŸŒ…. Come by and visit Booth 822 to learn about our comprehensive portfolio of products for neuroscience research! #SfN2025 #neuroscience

Learn moreπŸ§ͺhttp://bit.ly/4qoGnSG

12.11.2025 00:23 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Product Citation ✨

A study from the University of Alabama at Birmingham used StressMarq's NKCC2 Antibody to examine the impact of aquaporin insertion and diurnal patterns on fluid-electrolyte balance.

Paper 🌊 https://bit.ly/47YjP3V
Product πŸ’§ https://bit.ly/3WG1AtG

08.11.2025 18:18 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Human Tau (K18) Wild-Type PFFs (SPR-525) Order Human Tau (K18) Wild-Type PFFs (SPR-525) from StressMarq. High-quality reagents for neurodegenerative disease research.

New Product!⭐

StressMarq now offers Tau (K18) Wild-Type Pre-formed Fibrils. The Tau K18 fragment preserves the core pathogenic characteristics of full-length #tau while providing enhanced experimental control and reproducibility.

View the product details πŸ”Ž https://bit.ly/3LojZZF

07.11.2025 17:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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StressMarq will be exhibiting at #Neuroscience 2025 from November 16-19 in San Diego, CaliforniaπŸŒ…. Come by and visit Booth 822 to learn about our comprehensive portfolio of products for neuroscience research! #SfN2025 #neuroscience

Learn moreπŸ§ͺhttp://bit.ly/4qoGnSG

07.11.2025 00:23 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Product Citation πŸ’‘

Researchers at the University of Pittsburgh utilized StressMarq's ENaC gamma Antibody to identify Na+ transport through ENaC and the Na+/K+ ATPase as targets of inhibition by canagliflozin. #KidneyResearch

Paper πŸ§ͺ https://bit.ly/4oiRyea
Product πŸ”¬ https://bit.ly/4ottRQz

06.11.2025 21:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Human Tau (K18) Wild-Type Monomers (SPR-524) Order Human Tau (K18) Wild-Type Monomers (SPR-524) from StressMarq. High-quality reagents for neurodegenerative disease research.

New Product!πŸ’‘

StressMarq now produces Tau (K18) Wild-Type Monomers, optimized for #tauopathy research. These monomers readily form fibrils when incubated with heparin or seeded with PFFs, enabling precise modeling of disease mechanisms.

View the product details πŸ”¬ https://bit.ly/3JHYGl8

06.11.2025 19:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Product Citation 🍁 Researchers at the University of Alberta probed the connection between mutations in TMX2 & mitochondrial hyperactivity in #neurodevelopmental disorders, using StressMarq's ERp57 Antibody.

Paper 🌲 https://bit.ly/437ZW7R
Product 🌿 https://bit.ly/3vLSYbj

06.11.2025 17:46 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Microglial Receptors Mediate Tau Clearance The uptake of extracellular tau by neurons promotes misfolding & aggregation of intracellular tau. Microglia are able to internalize and degrade tau aggregates.

A multi-institutional collaboration in South Korea demonstrated that microglia-mediated uptake and clearance of extracellular #tau aggregates is modulated by complement receptor 4 (CR4), an innate immune receptor.

Learn more on the StressMarq blog 🦠 https://bit.ly/491njUq

#neurodegeneration

05.11.2025 14:17 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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StressMarq will be exhibiting at #Neuroscience 2025 from November 16-19 in San Diego, CaliforniaπŸŒ…. Come by and visit Booth 822 to learn about our comprehensive portfolio of products for neuroscience research! #SfN2025 #neuroscience

Learn moreπŸ§ͺhttp://bit.ly/4qoGnSG

01.11.2025 23:23 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Anti-ENaC alpha Antibody (SPC-403) - Rabbit Polyclonal Order Rabbit Anti-Rat ENaC alpha Polyclonal (SPC-403) from StressMarq. Suitable for WB, IHC, ICC/IF, IP. High-quality antibodies for scientific research.

Product Citation ✨ A study from the University of South Florida utilized StressMarq's #ENaC alpha Antibody to examine survival of kidney transplantation grafts & show that raising renal pH can prevent injury in #kidney transplants.

Paper 🌲 http://bit.ly/47iGAQ0
Product πŸƒ http://bit.ly/4qyqNnr

31.10.2025 23:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Human Amyloid Beta Peptide 1-40 + C-term Cysteine Monomers (SPR-533) Order Human Amyloid Beta Peptide 1-40 + C-term Cysteine Monomers (SPR-533) from StressMarq. High-quality reagents for neurodegenerative disease research.

πŸ’‘New Product!πŸ’‘

StressMarq now manufactures Amyloid Beta 1-40 + C-term Cysteine Monomers. Amyloid Beta is key to the pathology of #Alzheimer's disease, and the C-terminal Cysteine is optimized for maleimide conjugation.

View the product details hereπŸ”¬ http://bit.ly/4gWUc6y

31.10.2025 17:49 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Human Amyloid Beta Peptide 1-40 Monomers (SPR-530) Order Human Amyloid Beta Peptide 1-40 Monomers (SPR-530) from StressMarq. High-quality reagents for neurodegenerative disease research.

πŸ’‘New Product!πŸ’‘

Amyloid Beta 1-40 Monomers are a key isoform involved in the development of #Alzheimer’s disease by accelerating oligomerization and oxidative stress. StressMarq now provides Amyloid Beta 1-40 Monomers.

View the product details hereπŸ”¬ http://bit.ly/42pM5cJ

31.10.2025 17:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Anti-HSP90 Antibody - Mouse Monoclonal [H9010] Order Mouse Anti-Human HSP90 Monoclonal IgG2a from StressMarq. Suitable for WB, IHC, ICC/IF, IP, ELISA, AM. High-quality antibodies for scientific research.

Product Citation πŸ’‘ A study conducted by Memorial Sloan Kettering Cancer Center used StressMarq's #HSP90 Antibody to present a method for disease-contextual mapping of protein-protein interaction (PPI) networks.

Paper πŸ’ http://bit.ly/434sZt3
Product 🌺 http://bit.ly/4oIQrnU

30.10.2025 20:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Human Tau (K18) P301L Mutant PFFs (SPR-523) Order Human Tau (K18) P301L Mutant PFFs (SPR-523) from StressMarq. High-quality reagents for neurodegenerative disease research.

⭐New Product!⭐

StressMarq now provides Human Tau (K18) P301L Mutant Pre-formed Fibrils generated without heparin, offering an improved model for #tauopathy and #neurodegeneration studies. These PFFs induce neurotoxicity in primary mouse cortical neurons.

πŸ”¬Learn more here: http://bit.ly/46UZ4V1

30.10.2025 17:07 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Product Citation 🌟 A research team @mayoclinic.org investigated mechanisms driving #LewyBody pathology using a novel split biotin ligase technique. StressMarq’s #AlphaSynuclein PFFs were employed to model aggregation in vitro.

Paper 🌿https://bit.ly/4hB0VDy
Product 🌼 https://bit.ly/2u9YHV2

30.10.2025 16:46 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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StressMarq was proud to exhibit with #Neobioscience at the 9th Annual Meeting of the #Neurodegenerative Diseases Branch of the Chinese #Neuroscience Society! A great chance to engage with researchers, share our tools for #neuro research, and foster #GlobalScience collaboration. 🧠✨

29.10.2025 17:30 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Amyloid Beta Fibrillar Constructs | StressMarq StressMarq produces monomeric, fibrillar, and oligomeric amyloid beta protein constructs to support cutting-edge neurodegenerative disease research.

Alzheimer's News in Canada🧠🍁

Health Canada has approved #Lecanemab, a medication that slows the progression of #Alzheimer's disease by targeting amyloid plaque aggregation. This drug is the first of its kind approved in Canada!

Learn more about amyloid beta on our blogπŸ”Žhttp://bit.ly/4owcnmJ

28.10.2025 21:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Product Citation ✨ Researchers from Southwest Medical University used Stressmarq's Calreticulin Antibody to analyze the optimal therapeutic sequence of rhGM-CSF and #radiotherapy in treating pancreatic cancer.

PaperπŸ”¬ http://bit.ly/3WQy7x5
ProductπŸ§ͺ http://bit.ly/3J9uP53

25.10.2025 17:18 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Product CitationπŸ’‘A study out of Vanderbilt University used StressMarq's NHE3 #Antibody to examined how a dominant-negative Kir5.1 channel reduces kidney K+ flux.

Full PaperπŸ’ http://bit.ly/3WRq2IB
Product Details🌺 https://bit.ly/3ICiiD8

24.10.2025 23:17 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Human Amyloid Beta Peptide 1-40 + C-term Cysteine Monomers (SPR-533) Order Human Amyloid Beta Peptide 1-40 + C-term Cysteine Monomers (SPR-533) from StressMarq. High-quality reagents for neurodegenerative disease research.

πŸ’‘New Product!πŸ’‘

StressMarq now manufactures Amyloid Beta 1-40 + C-term Cysteine Monomers. Amyloid Beta is key to the pathology of #Alzheimer's disease, and the C-terminal Cysteine is optimized for maleimide conjugation.

View the product details hereπŸ”¬ http://bit.ly/4gWUc6y

24.10.2025 17:49 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Human Amyloid Beta Peptide 1-40 Monomers (SPR-530) Order Human Amyloid Beta Peptide 1-40 Monomers (SPR-530) from StressMarq. High-quality reagents for neurodegenerative disease research.

πŸ’‘New Product!πŸ’‘

Amyloid Beta 1-40 Monomers are a key isoform involved in the development of #Alzheimer’s disease by accelerating oligomerization and oxidative stress. StressMarq now provides Amyloid Beta 1-40 Monomers.

View the product details hereπŸ”¬ http://bit.ly/42pM5cJ

24.10.2025 17:02 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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