Arthritis Research Canada

Pregnancy Outcomes of Targeted Synthetic Disease-Modifying Antirheumatic Drugs Among Patients With Autoimmune Diseases: A Scoping Review - PubMed Our scoping review of evidence to date on the perinatal use of tsDMARDs reveal small sample sizes and a limited number of studies, all largely descriptive in nature. Findings highlight evidence gaps that preclude providers and patients from making informed decisions when considering the perinatal us …

Reported outcomes: congenital anomalies, preterm birth, spontaneous abortion, but data were limited.
⚠️ Major evidence gaps remain that preclude providers and patients from making informed decisions when considering the perinatal use of tsDMARDs.
🔗 Link to paper: pubmed.ncbi.nlm.nih.gov/39895048/

🧪📚 Our team's scoping review of tsDMARD use in pregnancy: From 6,712 records, only 8 studies met criteria (mostly case reports; n=1–116). Evidence was available on tofacitinib, baricitinib & upadacitinib; none on apremilast.

Prognosis and long term outcome of stenotic large vessel involvement in giant cell arteritis. Graphical abstract created using BioRender

Stenotic large vessel vasculitis is a rare and largely unknown subtype of giant cell arteritis (GCA). Retrospective study of 3,149 patients evaluated long-term outcome and prognosis of GCA with stenotic LVV

Arthritis & Rheumatology
acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

Spondyloarthritis preceding and following inflammatory bowel disease diagnosis and risk factors: a temporal trends analysis in a population-based cohort. A graphical abstract

In a nationwide cohort, spondyloarthritis diagnosis was associated with inflammatory bowel disease preceding & following its diagnosis. Findings also demonstrated temporal variability & highlighted clinical variables associated with SpA in IBD

A&R
doi.org/10.1002/art....
@predictibd.bsky.social

Randomised controlled trial led by @lli-1.bsky.social shows counselling combined with self-monitoring tools can help people with #RheumatoidArthritis manage their condition better. It can also improve symptoms like fatigue & mood.

🔗Link to paper: pubmed.ncbi.nlm.nih.gov/38152927/

Clinical Characteristics and Evolution of Interstitial Lung Disease in Subtypes of Idiopathic Inflammatory Myositis With Prevalent Lung Manifestation: A Retrospective Analysis Objective Interstitial lung disease (ILD) is common in idiopathic inflammatory myositis (IIM), particularly in antisynthetase syndrome (ASyS), antimelanoma differentiation-associated protein 5 (anti...

Bottom line: ILD may progress despite myositis remission. Ongoing pulmonary monitoring is essential 🫁

Link to paper: acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

ILD trajectories differ across IIM subsets. In a BC cohort (n=111), our team found that PmPPF occurred in 13.5%, mainly in anti-MDA5+ DM & antisynthetase syndrome, and was absent in scleromyositis. PmPPF associated with ↑ active disease, ↑ rapidly progressive ILD & ↑ transplant (20% vs 1.3%).

Published in Arthritis & Rheumatology @acr-journals.bsky.social : acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

New population-based study (n=229,300 T2D): GLP-1RAs & SGLT2is showed no ↑ or ↓ in overall autoimmune rheumatic disease risk vs. DPP4is. But SGLT2is were linked to ~50% ↓ risk of systemic ARDs. Study led by Dr. @derinkaracabeyli.bsky.social. See infographic 👇

Arthritis At Home 306 – A discussion on rheum-oncology and artificial intelligence in rheumatology | Arthritis At Home This episode of Arthritis At Home features Dr. Carrie Ye, an Associate Professor in the Department of Medicine at the University of Alberta.

JointHealth™ express - #ArthritisAtHome 306 – A discussion on rheum-oncology & artificial intelligence in rheumatology.

Watch now: arthritisathome.jointhealth.org?p=6743

#cancer #arthritis #AI @arthritispower.bsky.social @arthritistrainees.bsky.social @schroeder-uhn.bsky.social @achronicvoice.com

Takin hydroxychloroquine as prescribed- reduces hospitalizations snd save dollars!! - as simple as that!!

Glucagon-Like Peptide-1 Receptor Agonists, Sodium-Glucose Cotransporter-2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases. Graphical abstract created using BioRender

What is the impact of GLP-1RA & SGLT2i use on risk of developing autoimmune rheumatic diseases (ARD)? Data from a Canadian cohort of adults w/ type 2 diabetes showed SGLT2i use was assoc w/ lower risk of systemic ARDs, but neither GLP-1RA nor SGLT2i treatment was assoc w/ lower non-systemic ARD risk

🔗Link to full paper: acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

Our new study finds that early antimalarial adherence (PDC≥0.90) in incident RA/SLE is associated with lower acute care use & costs (BC cohort, 1997–2022; n=25,247): 11% ↓ admissions (RR 0.89), 21% ↓ hosp days (RR 0.79), −$550 CAD costs. Robust to sensitivity analyses. See graphical abstract below.

JointHealth™ express - Now Launching: JointHealth™ Education – #Arthritis and #MentalHealth. Click here to begin the course: bit.ly/JointHealthE...

Thank you Dr. Susan Bartlett for your help with this course! 🥰

@schroeder-uhn.bsky.social @arthritistrainees.bsky.social @arthritispower.bsky.social

Creation of these guidelines was led by the Canadian Rheumatology Association (CRA) and the Canadian Research Group of Rheumatology in Immuno-Oncology (CanRIO), with collaboration from several Arthritis Research Canada scientists.
📄 Paper 1: shorturl.at/7UPGf
📄 Paper 2: shorturl.at/PP718

New Canadian living guidelines address an important gap in cancer care: managing immune checkpoint inhibitors in patients with pre-existing inflammatory arthritis & systemic autoimmune rheumatic diseases. See GRADE-based, disease-specific recommendations in the embedded infographic.

Looking to get active with #arthritis? Yoga might be a great place to start!