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Shaun Cross

@shauntcross.bsky.social

Assistant Professor University of Nebraska Medical Center | Pathogen Genomics, Virome, and Vector Biology

2,094 Followers  |  1,043 Following  |  82 Posts  |  Joined: 24.08.2023
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Posts by Shaun Cross (@shauntcross.bsky.social)

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GitHub - hadley/genzplyr: dplyr but make it bussin fr fr no cap dplyr but make it bussin fr fr no cap. Contribute to hadley/genzplyr development by creating an account on GitHub.

Do you teach #rstats? Do your students complain about how lame and old-fashioned dplyr is? Don't worry: I have the solution for you: github.com/hadley/genzp....

genzplyr is dplyr, but bussin fr fr no cap.

06.11.2025 23:25 β€” πŸ‘ 460    πŸ” 167    πŸ’¬ 42    πŸ“Œ 55
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Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes - BMC Biology Background Arthropod-borne viruses (arboviruses) such as dengue virus (DENV) and Zika virus (ZIKV) pose a significant threat to global health. Novel approaches to control the spread of arboviruses foc...

πŸš€ Excited to share (with a little delay) my first first-author publication on #Vago genes in #mosquitoes! 🦟 🦠 Have a look to see how we questioned a mosquito immunity dogma and challenged the existing understanding of Vago-like genes as antiviral factors ⬇️

bmcbiol.biomedcentral.com/articles/10....

27.08.2025 12:10 β€” πŸ‘ 20    πŸ” 14    πŸ’¬ 1    πŸ“Œ 1

I hate how ONT words things. You basically have 6 sequencing runs that can have UP TO 24 samples in each run. Basically what you do is prep all the samples by amplifying 16S region, then pool and do the final adapter attachment

22.08.2025 19:16 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Our study is now published in @natcomms.nature.com and describes the 1st definitive identification of genetic variants linked to DENV susceptibility in Aedes aegypti mosquitoes. (1/3)

18.08.2025 12:05 β€” πŸ‘ 30    πŸ” 10    πŸ’¬ 3    πŸ“Œ 0

Still looking for candidates! Either DM or send me an email if interested.

14.08.2025 12:42 β€” πŸ‘ 2    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1

This piece on infection history as a driver of individual heterogeneity in infection outcomes was fun to think about and to write with @chadisaadroy.bsky.social and Mike Boots. Also suggest that systems like #Drosophila can offer useful tools to tackle the epidemiological consequences.

12.08.2025 09:57 β€” πŸ‘ 17    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
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πŸ“£ I'm recruiting a postdoc researcher to join my team for a project on mosquito-specific viruses and host interactions. Peep the job description & how to apply below. Perfect for soon-to-be or recent PhD graduates in mosquito vector biology 🦟 or arbovirology 🦠
πŸ—“οΈ Application deadline 31 August 2025

28.07.2025 09:25 β€” πŸ‘ 57    πŸ” 61    πŸ’¬ 1    πŸ“Œ 0

Have a postdoc position to start October 2025 to develop vector-borne pathogen genomic assays on ONT platforms. International travel will be required to Southeast Asia (Singapore and Malaysia). Looking for a hybrid position of wet lab and bioinformatics. DM me for more information. Please share!

21.06.2025 01:52 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1

Is Nebraska an area of interest? Happy to collect and send them.

16.06.2025 15:57 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Two good follows for this evening

@jenna-m-norton.bsky.social
@ianlmorgan.bsky.social

Two of the leaders at NIH who wrote the #BethedaDeclaration and are standing up and speaking out for all of us.

@standupforscience.bsky.social

11.06.2025 04:28 β€” πŸ‘ 101    πŸ” 34    πŸ’¬ 3    πŸ“Œ 1

Had a great time! Thanks @aphl.org and Uganda CPHL for coordinating the training!

08.06.2025 07:04 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Graphical abstract of: Temperature-dependent alternative splicing affects gene expression in Aedes aegypti mosquitoes midgut

Graphical abstract of: Temperature-dependent alternative splicing affects gene expression in Aedes aegypti mosquitoes midgut

In a new #RESInsectMolecBio article, temperature-dependent alternative splicing affects gene expression in #AedesAegypti #mosquitoes midgut 🦟 🧬

Learn more nowπŸ”½
doi.org/10.1111/imb.13002

@sassanasgari.bsky.social @gulianusslab.bsky.social @wiley.com

07.06.2025 11:41 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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A within-host infection model to explore tolerance and resistance A mathematical model of pathogen within-host dynamics and experimental validations elucidates the interplay between immune response, damage and pathogen proliferation, highlighting the limitations of ...

It is difficult to interpret single #pathogen burden during #infection. It is hard to untangle default in resistance and tolerance to explain #susceptibility. We help making sense of with-host dynamics and give tools to study infection, especially in #Drosophila.
elifesciences.org/articles/104...

06.06.2025 13:37 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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Sex Differences in Drosophila Intestinal Metabolism Contribute to Sexually Dimorphic Infection Outcome and Alter Gut Pathogen Virulence Sexual dimorphism in infection outcomes is a pervasive phenomenon, the underlying mechanisms of which remain incompletely understood. Here, utilizing Pseudomonas entomophila intestinal infection in Dr...

Happy to share our new preprint! We explored the mechanisms underlying differences between male and female #Drosophila in susceptibility to intestinal #infection. #symbiosky
#immunity #AcademicSky #insect #symbiosis

28.05.2025 19:46 β€” πŸ‘ 20    πŸ” 10    πŸ’¬ 1    πŸ“Œ 0
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In our latest study, we use #spatialtranscriptomics to characterize cold ischemic injury at multiple time points modeling a kidney transplant setting to reveal compartment-specific changes

Check out the preprint: www.biorxiv.org/content/10.1...

πŸ§΅πŸ‘‡ 1/n

29.05.2025 12:47 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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Autocycler: long-read consensus assembly for bacterial genomes Motivation Long-read sequencing enables complete bacterial genome assemblies, but individual assemblers are imperfect and often produce sequence-level and structural errors. Consensus assembly using T...

New preprint! Autocycler is a tool for long-read consensus assembly of bacterial genomes. It's like Trycycler but can be run fully automated (without any human intervention).
www.biorxiv.org/content/10.1...
(1/6)

21.05.2025 03:29 β€” πŸ‘ 78    πŸ” 38    πŸ’¬ 1    πŸ“Œ 0

Received exciting news about a project and will be opening a search for a postdoc. Focused in pathogen genomics--specifically vector-borne diseases. Looking for expertise in genomics, bioinformatics, and able to do some international travel. Please reach out to me if interested or know somebody!

14.05.2025 14:00 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Meeting the Moment Together We are returning from the AERA Annual Meeting in Denver reinvigorated and with a deep appreciation for all that scholars and higher education leaders are holding in this moment. Rapid shifts in fed...

FYI β€œSpencer Foundation, Alfred P. Sloan Foundation, William T. Grant Foundation and Kapor Foundation are providing quick turnaround grants of up to $25k for education scholars impacted by the abrupt NSF grant cancellations.” www.spencer.org/news/meeting...

02.05.2025 23:10 β€” πŸ‘ 260    πŸ” 201    πŸ’¬ 0    πŸ“Œ 6
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DIYNAFLUOR: An Affordable DIY Plug-and-Play Nucleic Acid Fluorometer for eDNA Quantification in Resource Limited Settings Nucleic Acid (NA) fluorometry is widely employed for quantifying environmental DNA (eDNA) samples and their downstream DNA sequencing libraries, owing to its sensitivity, accuracy, and speed. However,...

A Preprint for our ~$40 USD, open source, 3D printed DNA Fluorometer, the #DIYNAFLUOR, has just been posted to bioRxiv outlining its performance and applications for #eDNA analysis!πŸ¦•πŸ§ͺ🧬

A big thanks to all the co-authors!

Preprint
www.biorxiv.org/content/10.1...

Git
tinyurl.com/yfh33dsx

#science

17.12.2024 07:04 β€” πŸ‘ 49    πŸ” 21    πŸ’¬ 1    πŸ“Œ 4

100%!!! Send it here, learn about your ticks and help us understand tick borne diseases πŸŽ‰

03.05.2025 01:31 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

You can stick the tick in a ziplock bag and send it in a small padded envelope. Our website has the instructions and some pictures to show how to submit a tick through the program.

Never thought about gluing them to a postcard but that’s an interesting idea haha

02.05.2025 18:59 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Ticks can be quite the movers!Always feel free to now send them our way and we will happily help out

02.05.2025 18:55 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

πŸ˜‚ well if you need or want ticks from Nebraska I got you! There is no shortage here

02.05.2025 01:03 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Home Welcome to the Nebraska Tick Testing (NeTT) laboratory homepage! Learn more about how you can collect and submit ticks for testing.

Excited to announce that my research group is launching a *FREE* tick testing program called Nebraska Tick Testing (NeTT). We accept any ticks, both inside and outside Nebraska. We will identify the tick, screen it for pathogens, and provide a report. For more information visit: go.unmc.edu/nett

02.05.2025 00:56 β€” πŸ‘ 36    πŸ” 21    πŸ’¬ 3    πŸ“Œ 1
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Yee Mosquito Lab Visit the post for more.

🦟πŸ§ͺ ***I'm recruiting*** one student (M.S. or Ph.D.) to join my lab January 2026. Students need a 3.0 GPA and have an interest/experience in mosquito taxonomy, phenotypes, or ecology. Work on genetics/genomics is a plus. Deadline is 15 October 2025. US based students only. yeemosquitolab.org

24.04.2025 16:29 β€” πŸ‘ 24    πŸ” 19    πŸ’¬ 0    πŸ“Œ 1
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a cartoon of a man holding a frying pan and a spoon with red alert written above him ALT: a cartoon of a man holding a frying pan and a spoon with red alert written above him

ATTENTION: NSF GRANT RECIPIENTS

We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.

1/n

24.04.2025 21:09 β€” πŸ‘ 1041    πŸ” 919    πŸ’¬ 25    πŸ“Œ 43
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the word alert is in a purple circle ALT: the word alert is in a purple circle

ACTION ITEM-----ACTION ITEM

Implementation of Schedule F

This is what a lot of us have been worried about.

This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.

BUT THERE IS A COMMENT PERIOD...

1/n

23.04.2025 18:03 β€” πŸ‘ 364    πŸ” 447    πŸ’¬ 17    πŸ“Œ 59
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✨🦟✨HOW DO MOSQUITOES HAVE SEX? ✨🦟✨

Join us for a wild journey into hidden female control, rapidly evolving stimulation devices, fierce species competition, and DEADLY MOSQUITOES!

www.biorxiv.org/content/10.1...

20.04.2025 15:05 β€” πŸ‘ 61    πŸ” 29    πŸ’¬ 5    πŸ“Œ 5
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Comparative gene annotation of 304 species of Drosophilidae

I know you like #Drosophila and I know you like #Genomes - but do you also like #Genes? Coding DNA annotation of 304 species of Drosophilidae! www.biorxiv.org/content/10.1...

16.04.2025 06:21 β€” πŸ‘ 35    πŸ” 14    πŸ’¬ 1    πŸ“Œ 1
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The potential of attractive insecticide-treated nets (ITNs) in reducing malaria transmission: a modeling study Introduction Recent studies suggest that insecticide-treated nets (ITNs) may actively attract malaria vectors, increasing their likelihood of coming into contact with the insecticide while…

πŸ“ [Preprint] What if insecticidal bednets increased #mosquito attraction to humans? 🦟

We explored this counterintuitive effect using a transmission model for #malaria.

πŸ§ͺ Available on medRxiv: buff.ly/S0Wnn1n

#mathematicalmodeling #vectorcontrol #publichealth

15.04.2025 12:27 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0