Stephanie Olivier-Van Stichelen

Revealing the hidden role of sugars in cancer - Canadian Glycomics Network Revealing the Hidden Role of Sugars in Cancer Menu Research Research Security Technology Highlights An Introduction to Glycomics Call for Proposals Eligible Research Activities and Costs Corporate…

Cancer cells exploit sugars on their surfaces to evade immune detection and spread.
Glycomics research is essential to uncovering these hidden mechanisms and advancing new approaches to cancer detection and therapy.

🔗 Explore some current projects:

Open-source AI tool beats giant LLMs in literature reviews — and gets citations right Researchers can deploy the cheap and transparent model on their own computer system.

Researchers have published the recipe for an artificial-intelligence model that reviews the scientific literature better than some major LLMs are able to, and gets the citations correct as often as human experts do

go.nature.com/3NZ0CYo

STAND UP FOR SCIENCE.

🧪🇨🇦

Our Black/African American Business Resource Group honored the life and legacy of Dr. Martin Luther King Jr. through service. At Dr. Howard Fuller Collegiate Academy, team members decorated the student union, put up college flags and a college acceptance board and wrote letters of encouragement.

A tribute to Stuart A. Kornfeld (1936–2025) - John T. Milliken Department of Medicine A giant in the field of biomedical research, Stuart Arthur Kornfeld, MD (Figure 1), passed away in St. Louis on Sunday, August 17, 2025, following complications from Parkinson’s disease. Stuart was th...

A tribute to Stuart A. Kornfeld (1936–2025) such a giant in the field and mentors to many.

internalmedicine.wustl.edu/a-tribute-to...

A rapid, high-throughput assay for the detection of O-GlcNAcylation
#glycotime #CarbohydrateResearch

Potential new treatment for sepsis - Griffith News Griffith University researchers may have unlocked the secret to treating sepsis, with a Phase II clinical trial in China successfully concluding with

"Griffith University researchers may have unlocked the secret to treating sepsis, with a Phase II clinical trial in China successfully concluding with promising results."

Amazing #glycotime news! Super congrats @markvoni.bsky.social and colleagues! 👏🏻👏🏻 🥳🥳

news.griffith.edu.au/2026/01/15/p...

On this #MLKDay, we keep our eye on Dr. King's dream. We honor his legacy by building healthier communities and inspiring everyone to achieve their unique, best life - today and for generations to come.

Figure showing findings from studies reporting absenteeism risk associated with diabetes mellitus.

From our February issue: Dianna J. Magliano and colleagues outline the available evidence and highlights research gaps in our understanding of how diabetes mellitus affects work participation (£) go.nature.com/4sODQSU

Image of the front cover of a journal.

Our February issue is now live! Featuring Year in Review articles from across endocrinology & metabolism and Reviews on adipose, leptin & melanocortin signalling in infection, cellular senescence and diabetes in the workplace -> www.nature.com/nrendo/ #EndoSky #MedSky

🧪 #glycotime

Our lab works on various aspects of hormone regulation by O-GlcNAcylation, including pituitary hormones @aknier.bsky.social and placental hormones(Lily Massman).

So we wrote a review, "O-GlcNAcylation in Endocrinology: The Sweet Link".

Check it out!

academic.oup.com/endo/article...

Paracrine stimulation of brown adipose tissue vascularization by adipocyte O-GlcNAc signaling Brown adipose tissue is extensively vascularized, which is essential for its physiological activities. Li et al. show that nutrient/stress-sensing O-GlcNAc signaling in brown adipocytes dynamically adapts to environmental stimuli to stimulate brown adipose tissue vascularization and thermogenesis via a KCP-mediated paracrine mechanism.

Paracrine stimulation of brown adipose tissue vascularization by adipocyte O-GlcNAc signaling

ICYMI: Time-resolved multiomics profiling reveals chromatin O-GlcNAc modification promotes senescence-associated transcriptional program @natcomms.nature.com

Graphical abstract on the mechanism of action of the O-GlcNAc moiety

Glycosylation often functions to mediate protein folding, stability, and protein-protein interactions. Here, O-GlcNAcylation of histone H2B S112 allosterically activates E2 enzyme RAD6A and directly enhances its activity for H2B K120 monoubiquitylation

www.nature.com/articles/s41...

The O-GlcNAc Database just got a major upgrade!

New design + new tools
OGT & OGA variant pages
Ontology-based literature search
CytOVS for MS data integration

Made possible by support from @bwfund.bsky.social

oglcnac.mcw.edu

#OGlcNAc #glycotime #database

The Fehl lab shares their latest work on profiling glycoproteins in tissues. They find that O-GlcNAc modifies hundreds of metabolic and signaling proteins in skeletal muscle samples, now online at Glycobiology. #wsuchemistry #glycotime #ChemSky

academic.oup.com/glycob/artic...

Upcoming opportunities Calling all biochemistry and molecular biology educators! Share your teaching experiences and insights in ASBMB Today’s essay series. Submit your essay or pitch by Jan. 15, 2026.

🔬 Deadlines are approaching for several summer research programs, internships and career-exploration opportunities in the molecular life sciences.

Mentors & advisors — please share with your students! Many applications are due January – February.

➡️ Learn more:

PhD students’ taste for risk mirrors their supervisors’ Learned risk-taking behaviours can persist for years after leaving the lab — and even after taking on a new research topic.

A researchers’ propensity for risky projects is passed down to their doctoral students — and stays with trainees after they leave the laboratory

go.nature.com/4sHq58H

Stacked bar charts show percentages of survey respondents who said the U.S. was gaining ground, staying in about the same place or losing ground when it came to scientific achievement compared with other countries. As of October 2025, the data for all respondents was 13 percent gaining ground, 38 percent staying in about the same place, 47 percent losing. Among Republicans, the breakdown was 19 percent gaining, 49 percent staying put, and 32 percent losing. Among Democrats, the breakdown was 9 percent gaining, 25 percent staying put, and 65 percent losing.

A new report finds that a majority of Americans think the U.S. should be a world leader in science, but Democrats increasingly believe other countries are catching up. Check out the numbers below and learn more in the story here: www.scientificamerican.com/article/amer...

Our lab works on various aspects of hormone regulation by O-GlcNAcylation, including pituitary hormones @aknier.bsky.social and placental hormones(Lily Massman).

So we wrote a review, "O-GlcNAcylation in Endocrinology: The Sweet Link".

Check it out!

academic.oup.com/endo/article...

The O-GlcNAc Database just got a major upgrade!

New design + new tools
OGT & OGA variant pages
Ontology-based literature search
CytOVS for MS data integration

Made possible by support from @bwfund.bsky.social

oglcnac.mcw.edu

#OGlcNAc #glycotime #database

OGT-mediated O-GlcNAc of PINK1 Promotes the Progression of Obesity-related Hypertension via Regulating Mitophagy AbstractBACKGROUND. Obesity causes a variety of metabolic diseases, including hypertension. O-linked beta-N-acetylglucosamine (O-GlcNAc), a dynamic posttra

OGT-mediated O-GlcNAc of PINK1 Promotes the Progression of Obesity-related Hypertension via Regulating Mitophagy

🔗 academic.oup.com/ajh/article-... 🔒

Opportunities for Therapeutic Modulation of O-GlcNAc O-Linked β-N-acetylglucosamine (O-GlcNAc) is an essential, dynamic monosaccharide post-translational modification (PTM) found on serine and threonine residues of thousands of nucleocytoplasmic protein...

Excited to share "Opportunities for Therapeutic Modulation of O-GlcNAc" @acspublications.bsky.social Chemical Reviews with Alison Mody in the Woo lab, our contribution to an upcoming special issue "Drugging the Undruggable". (1/6) pubs.acs.org/doi/10.1021/... #glycotime

why is @bsky.app taking way longer than former Twitter to get my network going? anyone?

Glyco get-together exploring health and disease Meet the co-chairs of the 2025 ASBMB meeting on O-GlcNAcylation to be held July 10–13, 2025, in Durham, North Carolina. Learn about the latest in the field and meet families affected by diseases assoc...

Friendly reminder: There are just two days left to register for the 2025 ASBMB meeting on O-GlcNAcylation🟦! Meet co-chairs Michael Boyce & @ovslaboglcnac.bsky.social for a preview: asbmb.org/asbmb-today/....
⭐Thanks to our sponsors, including @brukercorporation.bsky.social & @epicypher.bsky.social.

O-GlcNAcylation in health and disease July 10–13, 2025 | Durham, N.C.

TODAY is early registration deadline for ASBMB’s O-GlcNAcylation🟦 in health & disease meeting, organized by Michael Boyce & @ovslaboglcnac.bsky.social.
➡️Register to save $50: www.asbmb.org/meetings-eve....
➡️Read this Q&A for a behind the scenes look at the program: www.asbmb.org/asbmb-today/....

I’m studying the impact of sugars and artificial sweeteners during pregnancy. With the loss of abortion right in a lot of states in the US, we are seeing an increase in pregnancy-related death and complications. Pregnancy research is

The US has been the best place to do science in the world for such a long time… this might not be the case soon!! We need to protect scientific research and medical education!