Antoine Zalc

Developmental Biology lost a giant yesterday 😔
May his legacy thrive and keep inspiring current and future generations of scientists

www.gurdon.cam.ac.uk/nobel-laurea...

😳😢

I got it! Macron thinks he’s Guardiola. He implanted constant movement in French politics
Please help us

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Happy Oct 4 y’all
#oct4 #pluripotency

Baguette secondary axis formation!
CRISPR is amazing ! #devbio

Can’t complain! Learning to be a PI is a fun ride
I heard you’re coming back to Europe !

WoW! Looks super interesting! Congrats Raquel !

Beautiful cover 🤩

Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4 - Nature Communications Here they perform a systematic dissection of OCT4 and reveal how intrinsically disordered regions can be used to serve specific functions during reprogramming and embryonic development. This can be exploited to engineer more efficient and specific reprogramming factors.

Hot off the press!

Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4

www.nature.com/articles/s41...

X-chromosome upregulation operates on a gene-by-gene basis at RNA and protein levels - Nature Communications Here, the authors investigate gene dosage compensation in mouse pluripotent stem cells to better understand the process of X-chromosome upregulation. They report that mammalian cells can sense when segments of one of the two X chromosomes are genetically deleted in cis and compensate gene expression by upregulation in trans.

www.nature.com/articles/s41...

Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging

www.biozentrum.unibas.ch/open-positio...

#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging

🚂 Sauvons les trains de nuit Paris-Berlin et Paris-Vienne Signez la pétition maintenant !

🚂 😴 A peine lancés et déjà supprimés ? Sauvons les trains de nuit Paris-Berlin et Paris-Vienne, un voyage bas-carbone largement plébiscité par ses utilisateurs et utilisatrices.

Pétition à signer ici ⤵️
agir.greenvoice.fr/petitions/sa...

La chouille! Pas entendu ça depuis l’école

Congrats Audrey! Super cool!

Featured resource: Facebase - the Node Our ‘Featured resource’ series aims to shine a light on the resources that support our research – the unsung heroes of the science world. In this post, we learn about the data and functionalities avai...

Featured resource: Facebase

In this post, we learn about the data and functionalities available at Facebase @facebase.bsky.social, and hear about new initiatives they are developing.

thenode.biologists.com/featured-res...

Early Career Opportunity
Mentorship & career development, access to world-class facilities, and a collaborative, supportive environment. We are particularly interested in researchers in Synthetic Dev. Biol. Mechanobiology and AI . #AcademicJobs #EarlyCareerResearcher #UCL #DevelopmentalBiology

📣 Our department is hiring an Assistant Professor in Evolutionary Cell and Molecular Biology to join the @weillinstitute.bsky.social PLS spread the word!
academicjobsonline.org/ajo/jobs/30607

The EMBL PhD programme is open until 13th October (entry ~Sep 2026):
www.embl.org/about/info/e...

We have three positions in microbial genomics at EMBL-EBI, including one in my group. Please do apply, or if you know anyone that would be interested pass on to them

Compost is a worm specialty

Keep calm & Listen to David Bowie

Figure 3: dh2 protein exhibits a relatively stable gradient along the posterior to anterior axis in iPSM. (A) Scheme of the knock-in strategy for generating a Cdh2-mScarlet fusion protein reporter line. Created in BioRender by Jia, X. (2025). https://BioRender.com/f9n6ph3. This figure was sublicensed under CC BY 4.0 terms. (B) Representative snapshots of Achilles and mScarlet channels 6 h after starting live imaging (105-h post induction). Dashed squares indicate the ROIs for quantitative plot of intensity. A, anterior; P, posterior. Dashed line in the mScarlet channel is used for plotting intensity along the posterior-anterior axis. Scale bars: 100 μm. (C) Plots of the pHes7-Achilles intensity along time measured using the ROIs in B. The purple and green lines indicate the mean of intensities of Cdh2-mScarlet and pHes7-Achilles, respectively, from three ROIs, and the light pink and grey lines represent the intensity from each single ROI. (D) Spatial smoothed plots of intensity from pHes7-Achilles (green) and CDH2-mScarlet (purple) channels along the posterior-anterior axis.

Cdh2 helps the segmentation clock keep time

This Research Highlight showcases the work from Xueqi Jia, Akihiro Isomura and Ryoichiro Kageyama:

journals.biologists.com/dev/article/...

My son is watching Goldorak with the signature tune sung in Japanese
So proud ! 🥲

Venez nombreux, pas besoin d’être millionaire pour aider la recherche. Peu importe le montant, chaque don sera bénéfique !

📢 Lancement de la campagne ATIP-Avenir 2026

@cnrsbiologie.bsky.social et @inserm.fr ouvre la campagne ATIP-Avenir 2026, destinée à soutenir des projets de recherche innovants portés par de jeunes chercheuses et chercheurs.

📅 Toutes les informations : buff.ly/5DH6mpd

EpiSci - Hi there! Our review “Mechanotransduction in stem cells” is finally published. With @carstenschulte4.bsky.social we provided a comprehensive picture, that aims to cover the whole mechanotransductive pathway from the cell microenvironment to the nucleus. 1/3 pubmed.ncbi.nlm.nih.gov/38729084/

🚨 Don’t miss it! Abstract submission closes Monday, Sept 15. frenchzebrafishmeeting.fr
Fantastic keynote speaker @KarinaYaniv and a great opportunity to connect with the @FrenchZebrafish Community. All talks will be in English. Join us! #FZM #zebrafish

YouTube video by Julien Cohen The most INSANE Bohemian Rhapsody Flashmob you will ever see!!

Why Paris? Because

www.youtube.com/watch?v=rfUE...

🎊🎉🎊🎉🎊🎉🎊🎉🎊🎉
Pleased to announce the start of the Institut Cochin Foundation !

On September 18th at 6 p.m., upon registration come or connect to learn about the fantastic research done at the Institut Cochin @institutcochin.bsky.social , meet the people that do it and call for donations!