petar glažar

Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social
doi.org/10.1016/j.ce...
Read the thread👇 for the highlights of our findings.

oh wow so accurate 🥹

🥳 Very grateful for the support of the ERC Starting Grant for my newly established lab! We will study how transposable elements contribute to mammalian embryonic development.
We will have positions available next year. Stay tuned!

It's that time of the year - @mdc-berlin.bsky.social Pride Symposium in its 4th edition with great talks and discussions on intersectionality and DEI in general. As Neil Young said on Waldbuehne the other day - "Times are rough, we gotta look out for each other" 🫶 #MdcDiversity

new fear unlocked. thanks 😆

Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature Genetics Activation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype c...

Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5

took my mom to his gig recently and we concluded iggy is like a naked mole-rat, but c.elegans makes more sense actually :)

Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease - Nature Reviews Molecular Cell Biology Transposable elements (TEs) comprise nearly half of the human genome. This Review discusses transcriptional and post-transcriptional mechanisms that repress TE activity, how TEs escape this suppressio...

We wrote a review on Transposable Elements (TEs) and almost all aspects of TE silencing and their roles in biological processes & disease.
www.nature.com/articles/s41...

Insights from #TCTeAC

this is happening! ☀️

I am heartbroken about the loss of many labs at the Weizmann Institute yesterday in the missile attack. Dear scientists there: please know that you are not alone. Like many many others, I support you and am standing by to help you in any way I can.

gotta catch em all ✅

#TCTeAC
... The Woodstock of Biology2 & Night Science was terminated by police arrival.
>The End<

Nobody apparently dared to take a picture but it's true.

1312

vibing with my gang on woodstock night science conference, day 3 #theconferencetoendallconferences #TCTeAC

a bald man wearing a plaid shirt and a black vest ALT: a bald man wearing a plaid shirt and a black vest

getting killed five seconds into the assasin game with 144 participants because your partner got you as a target #TCTeAC

🔥🔥🔥

People at home following the Woodstock of Biology treads
#theconferencetoendallconferences #TCTeAC

meeting old comrades at #TCTeAC day 1

What controls condensate composition and function beyond binding stoichiometry? We show that condensate microenvironments play a key role, and can be probed by a micropeptide killswitch in live cells. www.nature.com/articles/s41... in @nature.com ‬ with @yaotianzhang.bsky.social Denes Hnisz & team.

Conservation of regulatory elements with highly diverged sequences across large evolutionary distances Nature Genetics - Combining functional genomic data from mouse and chicken with a synteny-based strategy identifies positionally conserved cis-regulatory elements in the absence of direct sequence...

How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭
Check out our paper - fresh off the press!!!
We find widespread functional conservation of enhancers in absence of sequence homology
Including: a bioinformatic tool to map sequence-diverged enhancers!
rdcu.be/enVDN
github.com/tobiaszehnde...

I think at this point I am moslty learning new biology from Jordi's memes 🔥🔥

Sequencing reads get longer, aligners get faster, LLMs get smarter, Katy Perry goes to space, but I still cannot type RNase without autocorrect making it weird.

Our 3D study of the tumor microenvironment is finally out!

Play around with the data yourself at lung-3d-browser.mdc-berlin.de (Kudos to @danilexn.bsky.social👏 )

Many thanks to Nikolaus Rajewsky lab at @mdc-bimsb.bsky.social and everyone involved, it takes a village to raise a multimodal paper!

And on other news. My first contribution to science as a postdoc with @stirlingchurchman.bsky.social is out! We discuss the knowns and unknowns of post-transcriptional splicing. It was really fun to write with the great @karinechoquet

🪄✨