Thibaut Brunet's Avatar

Thibaut Brunet

@thibautbrunet.bsky.social

Evolutionary cell biology / evolution of morphogenesis / animal origins / choanoflagellates @institutpasteur.bsky.social https://research.pasteur.fr/en/team/evolutionary-cell-biology-and-evolution-of-morphogenesis/

5,519 Followers  |  2,721 Following  |  392 Posts  |  Joined: 05.09.2023
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Posts by Thibaut Brunet (@thibautbrunet.bsky.social)

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05.03.2026 08:44 — 👍 1    🔁 0    💬 0    📌 0

Thanks Iñaki 🙏 and thanks again for your useful comments on the manuscript!

05.03.2026 08:44 — 👍 0    🔁 0    💬 0    📌 0

Aggregation, choanoflagellates and extreme environments! Cool story!

04.03.2026 19:02 — 👍 4    🔁 1    💬 0    📌 0
Post image

Even more excited — our paper is featured on the cover of Science Advances!

Huge thanks to @alexandrejan.bsky.social who took this incredible photo of a ctenophore (aka comb jelly) and the editors.

Here’s the cover 👇

www.science.org/doi/10.1126/...

04.03.2026 20:54 — 👍 83    🔁 23    💬 3    📌 2

Thrilled to share that our preprint has been accepted in Science Advances! Grateful to an incredible team & collaborators.

Link: www.science.org/doi/10.1126/...

👏 @annaferraioli.bsky.social @maikekittelmann.bsky.social
@msarscentre.bsky.social @erc.europa.eu @hfspo.bsky.social #ctenophores

04.03.2026 20:49 — 👍 59    🔁 16    💬 2    📌 2

Thanks Rebecca! hope all is good with you (and congrats on your recent award)

04.03.2026 17:10 — 👍 1    🔁 0    💬 0    📌 0

Some of us know how sweet procrastination can be! If you feel the same, good news:

The abstract deadline for the EMBO Workshop has been extended to March 19!

Don’t miss the opportunity to present your work June 2–5 2026 in Oeiras, Portugal!

04.03.2026 16:56 — 👍 1    🔁 4    💬 0    📌 0

A bit late to the party- but this is one of the finest papers I have read in years. It is both super cool science, and does the near impossible in our field: grounding insights about the evolution of molecular mechanism in the ecological arena in which they (presumably) arose. It's a masterpiece.

04.03.2026 13:16 — 👍 30    🔁 3    💬 2    📌 0

Thanks Will! means a lot coming from you

04.03.2026 15:39 — 👍 1    🔁 0    💬 0    📌 0

Fantastic collaboration w/ @dbikard.bsky.social @audeber.bsky.social @rayanchikhi.bsky.social labs led by @jmouradesousa.bsky.social : We assessed the rates of variation of anti-phage systems in P4-like satellites and P2 helper phages. Quick conclusion: Huge variation! We focus on 4 key questions/5

03.03.2026 17:39 — 👍 41    🔁 18    💬 1    📌 1
Preview
Flexible paths to multicellularity Close relatives of animals can become multicellular if distinct individuals join together or if dividing cells remain attached. A species has been found to use both mechanisms.

This species can become multicellular using two mechanisms previously thought to be mutually exclusive

go.nature.com/4aTKdfF

04.03.2026 12:28 — 👍 33    🔁 15    💬 0    📌 1

We have extended the abstract deadline by a week! Looking forward to seeing you many of you here!

04.03.2026 12:07 — 👍 9    🔁 4    💬 0    📌 0

Really nice to see @marstonlab.bsky.social's News & Views piece cover the evolution of budding yeast centromeres in @nature.com. Check it out for a clear and concise breakdown of @maxhaase.bsky.social’s new paper and ours! 🧬

04.03.2026 08:29 — 👍 18    🔁 5    💬 0    📌 0
Contact/Job - Department of Molecular and Cellular Biology - UNIGE

You are finishing your PhD and looking to continue in science?

The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro....

Thanks for reposting!

03.03.2026 09:42 — 👍 39    🔁 45    💬 0    📌 1

Please tell me someone has written a paper about autophagy titled "Caveat mTOR"

02.03.2026 18:40 — 👍 48    🔁 10    💬 7    📌 0
La conférence de presse se déroulera au Collège de France, 11, place Marcelin Berthelot, 75005 à Paris, de 16h à 18h30, avec accès à partir de 15h30. Elle est ouverte au public mais les questions seront réservées aux journalistes. Elle comprendra des interventions sur la situation de l’Université et de la recherche aux Etats-Unis et en France :

Yasmine Belkaid, Directrice générale de l’Institut Pasteur  
Michel Feher, philosophe et co-fondateur de la maison d'édition ZoneBooks
Julien Gossa, chercheur au Laboratoire Sociétés, acteurs, gouvernement en Europe, Université de Strasbourg
Valérie Masson-Delmotte, chercheuse au Laboratoire des sciences du climat et de l'environnement, CEA
Nonna Mayer, chercheuse au Centre d'études européennes et de politique comparée,  Sciences Po

La conférence de presse se déroulera au Collège de France, 11, place Marcelin Berthelot, 75005 à Paris, de 16h à 18h30, avec accès à partir de 15h30. Elle est ouverte au public mais les questions seront réservées aux journalistes. Elle comprendra des interventions sur la situation de l’Université et de la recherche aux Etats-Unis et en France : Yasmine Belkaid, Directrice générale de l’Institut Pasteur Michel Feher, philosophe et co-fondateur de la maison d'édition ZoneBooks Julien Gossa, chercheur au Laboratoire Sociétés, acteurs, gouvernement en Europe, Université de Strasbourg Valérie Masson-Delmotte, chercheuse au Laboratoire des sciences du climat et de l'environnement, CEA Nonna Mayer, chercheuse au Centre d'études européennes et de politique comparée, Sciences Po

📣 Conférence Stand Up for Science
Vendredi 6 mars 2026|16h-18h30|Collège de France

Attaques contre les sciences et l’Université aux États-Unis et en France: comprendre les stratégies, cibles et effets et lancer des les mobilisations à venir en France, en écho à celles prévues aux États-Unis.

02.03.2026 12:33 — 👍 33    🔁 23    💬 2    📌 0

Thanks! 🙏

02.03.2026 09:19 — 👍 1    🔁 0    💬 0    📌 0
Video thumbnail

Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de

28.01.2026 16:10 — 👍 204    🔁 67    💬 4    📌 10

Deleted my data and account. I've had a paid OpenAI account for years.

Will be using other tools. LLMs have been fantastic for research and software development, but this is too much.

01.03.2026 17:46 — 👍 4    🔁 3    💬 1    📌 0

Do not miss this amazing conference! And if you are interested in mechanical forces in Evo-Devo, there is a symposium for you!

01.03.2026 11:29 — 👍 5    🔁 2    💬 1    📌 0
10th European Society for Evolutionary Developmental Biology Meeting 2026 The European Society for Evolutionary Developmental Biology is delighted to welcome you to the 10th biennial meeting, to be held at the University of Glasgow from June 9th - 12th in 2026.

We are really excited that Euro Evo Devo will take place here in Scotland from the 9th-12th June, at the University of Glasgow!

Deadline for Early Bird Registration and Abstract Submission are rapidly approaching in March so do register soon!

www.evodevoconference26.com/important-da...

26.02.2026 10:23 — 👍 38    🔁 26    💬 1    📌 1
Preview
The molecular evolution of vertebrate organs Nature Ecology & Evolution - This Review discusses recent advances in the molecular evolution of vertebrate organs, including rates of evolution of organs and cell types, molecular mechanisms...

Our internal organs are evolutionary marvels. New technologies are transforming our understanding of the evolution of vertebrate organs. You can find more by reading here:
rdcu.be/e5EgU
#EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜

25.02.2026 12:29 — 👍 138    🔁 52    💬 2    📌 5
Picture J. Zakany

Picture J. Zakany

Vendredi prochain 6 mars à 10h, début de mon cours 2026 @college-de-france.fr. Les relations conflictuelles entre les variations de l’ADN et l’évolution des structures🤓 L’ADN; cause proximale ou cause ultime? 🤔 Entrée libre, sortie libre! Amis Parisiens, 🙏RT 🤘

27.02.2026 09:09 — 👍 11    🔁 7    💬 0    📌 1

Interested in doing a PhD in tumor mechanobiology?

At Université Paris-Saclay, the upcoming PhD selection process is open, and I’m looking to put forward a candidate to join my lab.

If you’re excited about uncovering how mechanical signals regulate tumor progression, please get in touch!

24.02.2026 13:08 — 👍 12    🔁 11    💬 0    📌 0

I actually haven't read that one! although it's been on my list for a while. Now I should read it with Hydra in mind

28.02.2026 14:18 — 👍 0    🔁 0    💬 1    📌 0

Thanks James! Hope you crack their chromatine code soon. We are working to deposit all strains in repositories, but in the meantime are happy to distribute them - whoever wants to work on them, please don’t hesitate to ask

28.02.2026 09:41 — 👍 2    🔁 0    💬 0    📌 0

Thanks Omaya. May science be a refuge

28.02.2026 09:38 — 👍 5    🔁 0    💬 2    📌 0
Preview
Flexible paths to multicellularity Close relatives of animals can become multicellular if distinct individuals join together or if dividing cells remain attached. A species has been found to use both mechanisms.

Thanks to reviewers who helped us considerably improve and extend the work (which is now very large indeed), and to the editor @endofthepier.bsky.social for shepherding this to publication. S Coelho and
J Lotharukpong wrote a News & Views with a cleverly punny title. www.nature.com/articles/d41...

28.02.2026 08:12 — 👍 17    🔁 3    💬 3    📌 0
Schematic of a balance with parameters favoring clonality or aggregation

Schematic of a balance with parameters favoring clonality or aggregation

2) We showed that the balance between clonality and aggregation is finely regulated by environmental conditions: high salinity, short time and low cell density favor aggregation. Low salinity, long times and high cell density favor clonality. A versatile spectrum for a stochastic environment.

28.02.2026 08:12 — 👍 8    🔁 0    💬 2    📌 0
Cells aggregating preferentially with their close relatives

Cells aggregating preferentially with their close relatives

Polymorphic cadherin

Polymorphic cadherin

What has changed since the 1st preprint?
1) We isolated different C. flexe strains and showed that cells preferably aggregates with their close relatives + we found a polymorphic cadherin as a plausible kin recognition (and cell adhesion) locus. One prime target for gene editing in the future!

28.02.2026 08:12 — 👍 8    🔁 0    💬 1    📌 0