DrLeonardoNoto

#medfacts A commonly unrecognized cause of hypomagnesemia — too low serum mangnesium levels? Proton pump inhibitor drugs (drugs with a name that ends in “-prazole”). Other common causes include heavy alcohol intake, diuretic drugs, diarrheal illnesses, and nutritional insufficiency.

#medfacts Clostridiodes dificile colitis is an aggressive infection of the colon caused (usually) by antibiotics killing off the normal bowel bacteria and allowing C. diff to grow unchecked. Severe cases can necessitate removal of the colon or treatment via transplant of healthy donor stool.

#MedFacts All drugs are a risk vs benefits equation. That includes OTC drugs and supplements. Examples: NSAIDs like ibuprofen: great anti-inflammatory; can cause ulcers and kidney damage. PPIs like Nexium: great GERD relief; increase risk of pneumonia and osteoporosis.

Is my kid with asthma “on steroids?” Quite possibly, but they are anti-inflammatory steroids, not anabolic steroids. ”Steroids” are a broad class of biological molecules. Made from cholesterol. Natural examples include estrogen, testosterone, cortisol, and a lot of others. #medfacts

Your quoted percentage for GI bleeding after stroke seems very, very high btw.

Yes. Obviously get checked out immediately if you have GI bleeding. I don’t offer medical advice on Blue Sky, but I think that that recommendation is hopefully common sense.

I’ve done it for 13 years on Twitter. Mostly just for general interest, but also bc I am also an author and it gets my name out there.

There is evidence that suggests (not proves) that OTC azelastine nasal spray may be protective against COVID, influenza, and RSV infection. The mechanism is unknown. Warning: data from small studies demonstrating correlations like this sometimes turn out to be untrue.

#medfacts #medicine

Hematochezia = bright red blood per rectum. Usually (but not always) indicative of a lower GI bleed.

Melena = black ”tarry” appearing stool. Digested blood. Usually from an upper GI bleed.

The new borrowing caps for medical students per the BBB. Effective 2027. 50k/yr. 200k in aggregate. Median cost of med school public/private ~285k/~390k. #medfacts #Medicine

I was just reading an article about one of the most common uses of chatbots being for therapy. Needless to say, some of the recommendations that the bots made were both humorous and dangerous. Bad idea! #medicine #therapy #psychology

The pathophysiology of a knockout? Well, the physiology of consciousness isn’t fully understood, so… But in a nutshell, a hard blow to the head probably disrupts the reticular activating system (RAS) in the brainstem —> knock out. #medfacts #ufc #boxing

There is an old adage in medicine, “never be the first or the last to make use of a new drug.” Suzetrigine is probably going to be useful. It probably also has side-effects that we don’t know about yet. And it is new, which also means expensive, at the moment. #medfacts #science #medicine

A novel pain medication recently approved by the FDA, suzetrigine is a non-opioid drug that blocks pain signals peripherally, at the nerves at the site of the pain, rather than in the spinal cord or in the brain. A sodium channel blocker, it shouldn’t be habit-forming. #medfacts #medicine

How do gunshot wounds in injure? Two main ways. 1. Permanent cavity — the hole punched by the bullet. 2. Temporary cavity — essentially a shockwave caused by the bullet — if it disrupts a solid or fixed organ, it can kill too. #medfacts #Science #medicine

The difference btw carbon monoxide (CO) and carbon dioxide (CO2)? Both are odorless gases. CO is toxic in fairly small concentrations. You should have a detector for it at home. CO2 = byproduct of metabolism. Excessive amounts, most commonly caused by not breathing, are also toxic. #medfacts

Why do we breathe? It isn’t just oxygenation, but also ventilation. Ventilation is the removal of excess carbon dioxide via exhalation. Excessive carob dioxide —> bad things: acidosis, confusion, even coma. #medfacts #medicine #science

The best marker of refeeding syndrome is hypophosphatemia — low blood phosphorus levels. When rapidly fed, starving cells in the body use energy from food to make ATP (adenosine triphosphate), the “gasoline” that runs the body’s “engine.” #medfacts #medicine #science

In WWII, starving NAZI death camp victims started dropping dead after Allied soldiers gave them a bunch of food. The cause was Refeeding Syndrome — feeding starving people too quickly resulting in potentially fatal electrolyte abnormalities. #medfacts #medicine #Science

No one knows what caused Encephalitis Lethargic, or why the disease disappeared as suddenly as it appeared in the early 20th century. It may have been a sequela of Spanish Flu. Maybe. The movie “Awakenings” is about the mysterious disease. It stars Robert DeNiro.

#medfacts #medicine #science

The Life of a Colonial Fugitive Amazon.com: The Life of a Colonial Fugitive eBook : Noto, Leonardo: Kindle Store

Try out doc’s writing. This one is free on kindle until June 1st :-)

#historicalfiction #history #revolutionarywar #militaryhistory #kindle #kindleprime

www.amazon.com/Life-Colonia...

The Life of a Colonial Fugitive Amazon.com: The Life of a Colonial Fugitive eBook : Noto, Leonardo: Kindle Store

Try out doc’s writing. This one is free on kindle until June 1st :-)

#historicalfiction #history #revolutionarywar #militaryhistory #kindle #kindleprime

www.amazon.com/Life-Colonia...

No one knows what caused Encephalitis Lethargic, or why the disease disappeared as suddenly as it appeared in the early 20th century. It may have been a sequela of Spanish Flu. Maybe. The movie “Awakenings” is about the mysterious disease. It stars Robert DeNiro.

#medfacts #medicine #science

A interesting factoid: The term "vaccine" was derived from the Latin word for cow, "vacca," by Dr. Jenner (cowpox vaccine for smallpox).

#medfacts #medicine #science #history

Hemophilia A is common in males in the Royal Families of Europe--a sporadic mutation in Queen Victoria spread throughout the royals.

#medfacts #science #genetics #medicine

Medical lingo.

“Intern” — a physician in their first year of training after medical school.

“Internist” — an internal medicine doctor.

“Medicine” — internal medicine (as opposed to surgery, OB-Gyn, etc.)

A bit of doctor humor. Where do you hide a $100 bill from a surgeon? In a medical journal. Where do you hide it from an internist (internal medicine doctor)? Under the patient’s hospital gown. #medfacts #medicine

Whelp, we have a case of measles reported in Iowa. Get ready to party like it’s 1925…

A commonly missed cause of confusion in hospitalized elderly patients — urinary retention. Postoperative elderly pt on narcotics who becomes confused? Don’t forget this on your differential!

#medfacts #medicine #delirium

What is the difference btw a “broken bone” and a “fracture”?

It’s a trick question. Fracture = break! “Fracture” is the medical term btw.

#medfacts #medicine