bioRxiv Cell Biology

Coordinated and compartmentalized functions of CAII and CAIV establish a dual pH-regulatory mechanism essential for sperm maturation and capacitation https://www.biorxiv.org/content/10.1101/2025.10.13.681600v1

Cyp7b1-inhibiting azoles as novel enhancers of hematopoietic stem and progenitor cell mobilization https://www.biorxiv.org/content/10.1101/2025.10.13.682145v1

Phosphoinositide lipids have bidirectional and spatially distinct roles in filopodial dynamics https://www.biorxiv.org/content/10.1101/2025.10.13.681625v1

Distinct 5' and 3' Coverage Biases Shape Transcriptome Interpretation in Nanopore Direct RNA versus PCR-cDNA Sequencing https://www.biorxiv.org/content/10.1101/2025.10.13.681987v1

Restoration of Spermatogenesis is Dependent on Activation of a SPRY4-ERK Checkpoint Following Germline Stem Cell Damage https://www.biorxiv.org/content/10.1101/2025.10.12.681919v1

Peroxisome protein import deficiency causes heart failure in mouse and human https://www.biorxiv.org/content/10.1101/2025.10.13.681307v1

High-Purity Enrichment of Extracellular Vesicles from Diverse Sources by Conventional and Image-Based Fluorescence Activated Cell Sorters for Robust Downstream Applications https://www.biorxiv.org/content/10.1101/2025.10.12.681862v1

The neuronal fate determinants SOX4/11 control mitotic fidelity of adult hippocampal precursor cells https://www.biorxiv.org/content/10.1101/2025.10.13.682016v1

Functional profiling of extracellular vesicles from boar reproductive fluids https://www.biorxiv.org/content/10.1101/2025.10.11.681790v1

A microexon in Arp2 alters tissue-specific Arp2/3-generated actin structures https://www.biorxiv.org/content/10.1101/2025.10.12.681909v1

MYOSIN IIA MOTOR REGULATES ATTACHING-EFFACING BACTERIA INTERACTIONS WITH INTESTINAL EPITHELIUM https://www.biorxiv.org/content/10.1101/2025.10.11.681730v1

Complement Factor H and its C. elegans homolog regulate IFT52/OSM-6 and CNG channel localization in sensory neurons https://www.biorxiv.org/content/10.1101/2025.10.10.681644v1

Age Associated Increase in Microglia Inflammation and Phagocytosis in the Adult Neural Stem Cell Niche. https://www.biorxiv.org/content/10.1101/2025.10.10.681517v1

Cell cycle oscillations in a polarity network facilitate state switching by morphogenetic cues https://www.biorxiv.org/content/10.1101/2025.10.12.681824v1

Rax1/2 promote memory of growth by early Ras1 activation to maintain polarity across generations https://www.biorxiv.org/content/10.1101/2025.10.10.681675v1

Viral replication and interferon responses in bronchial epithelia is enhanced by Th17 cells https://www.biorxiv.org/content/10.1101/2025.10.10.681711v1

Comprehensive profiling of transcription factors for reprogramming human astrocytes to neuronal cells through endogenous CRISPR-based gene activation https://www.biorxiv.org/content/10.1101/2025.10.11.681828v1

ACETYLATED α-TUBULIN LYSINE 394 IS CRITICAL FOR AXON OUTGROWTH IN THE ADULT MUSHROOM BODIES OF DROSOPHILA MELANOGASTER https://www.biorxiv.org/content/10.1101/2025.10.10.681650v1

Efficient and reliable measles reprogramming platform for the generation of human iPSC https://www.biorxiv.org/content/10.1101/2025.10.10.677451v1

Displaced myonuclei are attributable to both resident myonuclear migration and stem cell fusion during mechanical loading in adult skeletal muscle https://www.biorxiv.org/content/10.1101/2025.10.10.681647v1

Oscillatory and elevated flow distinctly regulate gene expression in human coronary artery endothelial cells https://www.biorxiv.org/content/10.1101/2025.10.10.681055v1

A Fkh1/2 binding site array in the WHI5 promoter drives sub-scaling transcription https://www.biorxiv.org/content/10.1101/2025.10.10.681508v1

Optogenetic control of PLC-γ1 activity polarizes cell motility https://www.biorxiv.org/content/10.1101/2025.10.09.681531v1

Novel Role of AcylCoA:cholesterol acyltransferase 1 (ACAT1/SOAT1) in Diabetic Retinopathy https://www.biorxiv.org/content/10.1101/2025.10.09.681484v1

Quality-control Normalization of Fluorescence Microscopy Morphometry and Colocalization Measurements for Improved Accuracy and Cross-instrument Reproducibility https://www.biorxiv.org/content/10.1101/2025.10.09.681494v1

Single-cell lineage tracing identifies hemogenic endothelial cells in the adult mouse bone marrow https://www.biorxiv.org/content/10.1101/2025.10.09.681472v1

Combining FRET and super-resolution microscopy reveals kinase activation and mitochondrial activity at the nanoscale https://www.biorxiv.org/content/10.1101/2025.10.10.681576v1

Cellular Selectivity Analyses Reveal Distinguishing Profiles for Type II Kinase Inhibitors https://www.biorxiv.org/content/10.1101/2025.10.09.681452v1

Kinase KEY1 controls pyrenoid condensate size throughout the cell cycle by disrupting phase separation interactions https://www.biorxiv.org/content/10.1101/2025.10.09.681382v1

Endosome-associated Rab GTPases control distinct aspects of neural circuit assembly https://www.biorxiv.org/content/10.1101/2025.10.09.681358v1