A novel mechanism for centrosome expulsion ensures metabolic activity in polyploid cells https://www.biorxiv.org/content/10.1101/2025.08.01.668089v1
03.08.2025 11:30 — 👍 1 🔁 1 💬 0 📌 0@biorxiv-cellbio.bsky.social
A novel mechanism for centrosome expulsion ensures metabolic activity in polyploid cells https://www.biorxiv.org/content/10.1101/2025.08.01.668089v1
03.08.2025 11:30 — 👍 1 🔁 1 💬 0 📌 0Organelle membrane-associated proteins recruit cGAS via phase separation to facilitate its membrane localization https://www.biorxiv.org/content/10.1101/2025.08.01.668185v1
03.08.2025 07:30 — 👍 3 🔁 1 💬 0 📌 0Evaluating Labelling Efficiency of Commercial SPIONs in Mesenchymal Stem/Stromal Cells for Magnetic Particle Imaging Applications https://www.biorxiv.org/content/10.1101/2025.08.02.668266v1
03.08.2025 06:30 — 👍 0 🔁 0 💬 0 📌 0Astrocytic Ceruloplasmin Deficiency Triggers Iron Toxicity and Neurodegeneration in a LRRK2 Parkinson's Tri-Culture Model https://www.biorxiv.org/content/10.1101/2025.08.01.668099v1
03.08.2025 05:30 — 👍 0 🔁 0 💬 0 📌 0Targeting CyclinD1-CDK6 to Mitigate Senescence-Driven Inflammation and Age-Associated Functional Decline https://www.biorxiv.org/content/10.1101/2025.08.01.668243v1
03.08.2025 04:30 — 👍 0 🔁 0 💬 0 📌 0A parenchymal niche regulates pluripotent stem cell function in planarians https://www.biorxiv.org/content/10.1101/2025.08.01.668211v1
03.08.2025 04:30 — 👍 0 🔁 0 💬 0 📌 0Ashwin and FAM98 paralogs define nuclear and cytoplasmic RNA ligase complexes for tRNA biogenesis and the unfolded protein response https://www.biorxiv.org/content/10.1101/2025.08.01.668163v1
03.08.2025 04:30 — 👍 2 🔁 2 💬 0 📌 0Tropomyosin 1 promotes platelet adhesion and clot contraction separate from its roles in developmental hematopoiesis https://www.biorxiv.org/content/10.1101/2025.07.31.667883v1
03.08.2025 02:30 — 👍 0 🔁 0 💬 0 📌 0Mammalian cells evacuate and shelter mitochondrial DNA from destruction following hypoxia response-induced mitophagy https://www.biorxiv.org/content/10.1101/2025.08.01.667885v1
03.08.2025 02:30 — 👍 2 🔁 1 💬 0 📌 0CIAdex: Single-Cell FTIR Spectral Fingerprinting for Cell Identity Verification and Aging Quantification in Therapeutic Cell Manufacturing https://www.biorxiv.org/content/10.1101/2025.07.31.667910v1
03.08.2025 02:30 — 👍 0 🔁 0 💬 0 📌 0Muscle stem cells produce a protective Fibrillin-1 matrix to prevent precocious activation. https://www.biorxiv.org/content/10.1101/2025.08.02.666604v1
03.08.2025 02:30 — 👍 0 🔁 0 💬 0 📌 0Angulin-1/LSR inhibition transiently disrupts the blood-tumor barrier to enhance doxil permeability and impair malignant glioma progression https://www.biorxiv.org/content/10.1101/2025.07.31.667901v1
02.08.2025 18:30 — 👍 0 🔁 0 💬 0 📌 0Iterative delivery of mRNA by MEFI https://www.biorxiv.org/content/10.1101/2025.07.31.667827v1
02.08.2025 16:30 — 👍 2 🔁 0 💬 0 📌 0Cryo-EM structures of Egl-BicD-RNA complexes reveal how diverse mRNAs are selected for subcellular localization https://www.biorxiv.org/content/10.1101/2025.08.02.668268v1
02.08.2025 14:30 — 👍 2 🔁 3 💬 0 📌 0Functional integrity of the SEL1L-HRD1 complex is critical for ERAD and organismal viability https://www.biorxiv.org/content/10.1101/2025.08.01.668162v1
02.08.2025 12:30 — 👍 0 🔁 0 💬 0 📌 0Structures of dynamic interactors at native proteasomes by PhIX-MS and cryoelectron microscopy https://www.biorxiv.org/content/10.1101/2025.07.31.667872v1
02.08.2025 10:30 — 👍 1 🔁 0 💬 0 📌 0Deciphering the oxidative modifications via disulfide mapping https://www.biorxiv.org/content/10.1101/2025.07.30.666989v1
02.08.2025 07:30 — 👍 0 🔁 0 💬 0 📌 0Secretion and transfer of adipose lipoprotein lipase utilizes neutral sphingomyelinase 2 generated exosomes https://www.biorxiv.org/content/10.1101/2025.07.31.665751v1
02.08.2025 05:30 — 👍 0 🔁 0 💬 0 📌 0A xeno-free protocol for rapid differentiation of human iPSC-derived microglia from the KOLF2.1J reference line. https://www.biorxiv.org/content/10.1101/2025.07.28.667242v1
01.08.2025 14:30 — 👍 1 🔁 0 💬 0 📌 0Replisome progression regulates R-loop mediated transcriptional repression https://www.biorxiv.org/content/10.1101/2025.07.29.667376v1
01.08.2025 14:30 — 👍 1 🔁 0 💬 0 📌 0Vav2 is a master regulator of repair against bacterial pore-forming toxins. https://www.biorxiv.org/content/10.1101/2025.07.31.668026v1
01.08.2025 11:30 — 👍 0 🔁 0 💬 0 📌 0Clathrin-mediated endocytosis of ERECTA family receptors is essential for proper stomatal development in Arabidopsis https://www.biorxiv.org/content/10.1101/2025.07.31.668009v1
01.08.2025 11:30 — 👍 1 🔁 0 💬 0 📌 0Cdc42 regulates apical membrane fusion via the Rab11a-VAMP2 pathway in salivary gland acinar cells https://www.biorxiv.org/content/10.1101/2025.07.31.667845v1
01.08.2025 11:30 — 👍 0 🔁 0 💬 0 📌 0Brain biomechanics governs mitotic fidelity of embryonic neural progenitors https://www.biorxiv.org/content/10.1101/2025.07.31.667957v1
01.08.2025 10:30 — 👍 2 🔁 0 💬 0 📌 1The hidden predictors of human haematopoietic clonal fate https://www.biorxiv.org/content/10.1101/2025.07.28.667115v1
01.08.2025 10:30 — 👍 1 🔁 0 💬 0 📌 0BBSome-Mediated Clearance of Ubiquitinated IMPG2 Defines a Constitutive Ciliary Retrieval Pathway in Photoreceptors https://www.biorxiv.org/content/10.1101/2025.07.29.667331v1
01.08.2025 10:30 — 👍 0 🔁 0 💬 0 📌 0Measurements of Contractility in Actin Convergence Zone and KIF11-Inhibited Mitotic Spindles https://www.biorxiv.org/content/10.1101/2024.06.28.601275v1
01.08.2025 06:30 — 👍 0 🔁 0 💬 0 📌 0RNF13 Regulates the Endolysosomal Pathway Through Interaction with the Small GTPase Arl8B https://www.biorxiv.org/content/10.1101/2025.07.31.667977v1
01.08.2025 04:30 — 👍 2 🔁 1 💬 0 📌 0Early detection of oxidative stress in mammary epithelial cells by using secreted Cyclophilin A as a marker in the milk. https://www.biorxiv.org/content/10.1101/2025.07.29.667364v1
01.08.2025 04:30 — 👍 0 🔁 0 💬 0 📌 0Paternal ancestral gestational exposure to neonicotinoid thiacloprid induces transgenerational alteration in DNA methylation germline germline-specific genes in female ovaries. https://www.biorxiv.org/content/10.1101/2025.07.29.665494v1
01.08.2025 04:30 — 👍 0 🔁 0 💬 0 📌 0