Julia Frunzke's Avatar

Julia Frunzke

@frunzkelab.bsky.social

Professor at Forschungszentrum Jülich and HHU Düsseldorf. Phage-host interaction, regulatory networks, metabolic engineering, SPP 2330

456 Followers  |  285 Following  |  52 Posts  |  Joined: 09.01.2025
Posts Following

Posts by Julia Frunzke (@frunzkelab.bsky.social)

Fantastic collaboration w/ @dbikard.bsky.social @audeber.bsky.social @rayanchikhi.bsky.social labs led by @jmouradesousa.bsky.social : We assessed the rates of variation of anti-phage systems in P4-like satellites and P2 helper phages. Quick conclusion: Huge variation! We focus on 4 key questions/5

03.03.2026 17:39 — 👍 35    🔁 17    💬 1    📌 1
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Save the date for the next International Conference on Gram-Positive Bacteria which will take place between 29 June–2 July 2027. The organizers (@annadragos.bsky.social, @polonca32.bsky.social, and Ines Mandic-Mulec) look forward to welcoming you to Ljubljana, Slovenia

03.03.2026 14:08 — 👍 16    🔁 10    💬 1    📌 0

@spp2330.bsky.social

04.03.2026 19:35 — 👍 1    🔁 0    💬 0    📌 0
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New post-doctoral research position in my phage-host interactions (Phi) laboratory in @otagomicroimmuno.bsky.social at @universityofotago.bsky.social New Zealand. The project is focused on defences against jumbo phages. Please share and if interested apply using the link in the comments.

04.03.2026 00:20 — 👍 45    🔁 44    💬 5    📌 1
Assistant/Associate/Full Professor Computational Biology Assistant/Associate/Full Professor Computational Biology

Join us as Assistant/Associate/Full Professor Computational Biology at Institute of Biology Leiden (IBL) / @leidenscience.bsky.social / @unileiden.bsky.social

Application deadline on 15 March 2026
👇
careers.universiteitleiden.nl/job/Assistan...

26.02.2026 10:52 — 👍 20    🔁 22    💬 0    📌 0

Cell death is a fundamental mechanism of antiviral immunity across diverse organisms, including bacteria. As my final PhD project with @jbdsf.bsky.social, I was curious whether cell death is required for successful immunity with the ancient cGAS pathway known as ‘CBASS.’

Spoiler – the answer is no!

26.02.2026 16:25 — 👍 32    🔁 14    💬 2    📌 2

Glückwunsch Lena!

23.02.2026 21:26 — 👍 4    🔁 0    💬 0    📌 0
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Please RT:
Looking forward to our International Symposium on "Microbial Networking - from organelles to cross-kingdom communities".
Highlight of our first funding period of our Collaborative Researc Center @mibinet.bsky.social, @dfg.de

www.sfb1535.hhu.de/mibinet

@hhu.de , @fz-juelich.de

19.02.2026 14:45 — 👍 10    🔁 9    💬 1    📌 0
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Lasse presents our CRC1535 MibiNet project at the first RNA confluence meeting at the EMBL.
@rhinelandrna.bsky.social @mibinet.bsky.social

19.02.2026 14:09 — 👍 7    🔁 3    💬 0    📌 0
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PhD advertisement - Pausch lab | Patrick Pausch | 15 comments Please share! 📤 The Pausch lab at Vilniaus universitetas / Vilnius University is looking to recruit PhD students to work on: ⚔️ 🛡️: Bacterial Immune Systems (CRISPR, retrons, & beyond) 🧬 ✂️: De...

Great opportunity to join the lab of @patrick-pausch.bsky.social !

www.linkedin.com/feed/update/...

23.01.2026 12:24 — 👍 5    🔁 5    💬 0    📌 0
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Save the date, please RT:

Looking forward to an exciting International Symposium @spp2330.bsky.social "New concepts in prokaryotic virus-host interactions".

October 5-7, 2026; Harnack-Haus Berlin (Germany).

@dfg.de @hhu.de @fz-juelich.de

14.01.2026 14:41 — 👍 29    🔁 19    💬 1    📌 0

Congratulations! Nice to see this published!

14.01.2026 08:58 — 👍 1    🔁 0    💬 0    📌 0
A Novel Biosensor for Ferrous Iron Developed via CoBiSe: A Computational Method for Rapid Biosensor Design Genetically encoded biosensors enable the monitoring of metabolite dynamics in living organisms. We present CoBiSe, a computational biosensor design approach using Constraint Network Analysis to ident...

We Are very happy that our Paper was published. Thank to everyone involved

pubs.acs.org/doi/10.1021/...

@mibinet.bsky.social @mfeldbruegge.bsky.social @frunzkelab.bsky.social

12.01.2026 09:48 — 👍 10    🔁 8    💬 1    📌 0

Great collaboration with @hoeferlab.bsky.social, @aharms485.bsky.social, @pozhydaieva.bsky.social, @usadellab.bsky.social, @vivienrosenthal.bsky.social

14.01.2026 08:57 — 👍 6    🔁 1    💬 0    📌 0

This shows that "abortive infection" phenotypes are not neccessarily in all cases a "last line" of defense, but may be the consequence of mechanisms interferring with early steps in the phage life cycle.
We further show synergy of daunorubicin with RM systems targeting the FST region T5 phages.

14.01.2026 08:57 — 👍 3    🔁 1    💬 1    📌 0
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Happy to share our recent preprint:
"DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity"

www.biorxiv.org/content/10.6...

@spp2330.bsky.social, @mibinet.bsky.social, @dfg.de @hhu.de @fzj.bsky.social

14.01.2026 08:57 — 👍 44    🔁 26    💬 2    📌 0
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Postdoc (m/f/d) in Endosymbiosis Research

📢Postdoc position available!🧪🧫🧬
Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions.
Full details & application: karriere.hhu.de//index.php?a....
Please help us get the word out!

25.11.2025 11:24 — 👍 24    🔁 35    💬 0    📌 0
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Vesicle-coupled mRNA transport and translation govern intracellular organelle networking - EMBO Reports Eukaryotic cells are highly compartmentalized, enabling sophisticated division of labour. For example, genetic information is stored in the nucleus while energy is produced in mitochondria. Despite th...

Very happy to See This Published!!!! Thanks for the collaboration

link.springer.com/article/10.1...

16.12.2025 18:21 — 👍 11    🔁 6    💬 1    📌 1
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Bacteria sense virus-induced genome degradation via methylated mononucleotides Phages often degrade the genome of their bacterial host to individual nucleotides and use these nucleotides to build their own genome. In this study, we describe a bacterial defense system that direct...

www.biorxiv.org/content/10.1...

@soreklab.bsky.social Sorek lab does it again! Such a cool signal to specifically detect the event of genome degradation by a phage

08.11.2025 17:22 — 👍 22    🔁 3    💬 1    📌 0

Very nice to meet @heermann-lab.bsky.social and @gebhardlab.bsky.social in Mainz! Thank you for the warm welcome!

08.11.2025 08:00 — 👍 3    🔁 0    💬 1    📌 0
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Another fantastic SPP 2330 meeting! Thank you all for three inspiring days of science, collaboration, and novel ideas. See you next year at our international symposium in Berlin, October 5–7, 2026! @dfg.de @fz-juelich.de @hhu.de

10.10.2025 10:47 — 👍 14    🔁 1    💬 1    📌 0
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That was a phagetastic @spp2330.bsky.social meeting again! Thanks to everyone to your excellent presentations. Keep the spirit ☺️

@dfg.de

Already looking forward to our International Symposium in Berlin next year (October 5-7, 2026; Harnack-Haus)

10.10.2025 17:59 — 👍 13    🔁 0    💬 0    📌 0
Junior Group Leader - Phage Biology & Biotechnology As a leading research institution for microbial biotechnology the Institute of Bio- and Geosciences - Biotechnology (IBG-1, https://www.fz-juelich.de/de/ibg/ibg-1 ) at the Forschungszentrum Jülich foc...

Please RT:
We have an opening for a junior group leader position in „Phage Biology & Biotechnology“.
www.fz-juelich.de/de/karriere/...

Interested candidates are encouraged to contact me via email for further details.

@spp2330.bsky.social; @mibinet.bsky.social

08.10.2025 06:50 — 👍 35    🔁 57    💬 0    📌 1
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Video compilation from our #türenauf mit der Maus Tag today! #outreach #chemsky @hhu.de @sophieguti.bsky.social @joguti.bsky.social @markussuta.bsky.social @chemiehhu.bsky.social

03.10.2025 16:45 — 👍 35    🔁 12    💬 0    📌 0
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Just returning from a fantastic symposium celebrating my former postdoc mentor, Julia Vorholt, on receiving the Novonesis Biotechnology Prize! Huge congratulations to Julia — and to the Novo Nordisk Foundation on an outstanding choice!

04.10.2025 06:43 — 👍 20    🔁 3    💬 0    📌 1
DMF: Tenure Track Assistant Professor towards Associate Professor in Molecular Microbiology - Site des postulations FBM

New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...

10.06.2025 13:53 — 👍 112    🔁 162    💬 0    📌 8

We have two new positions, a PhD and a Post doc at #InstituteofBiologyLeiden within our @microclockerc.bsky.social #ERCSyG project to discover interaction of #circadianclocks between Bacillus subtilis and Arabidopsis

please share these with your network! 🙏

links below👇
[1/3]

10.06.2025 07:13 — 👍 38    🔁 47    💬 1    📌 2
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Congratulations to Rebecca Hinrichs on her first senior-author paper! @synmikro.bsky.social @unimarburg.bsky.social

academic.oup.com/nar/article/...

06.06.2025 16:52 — 👍 16    🔁 4    💬 0    📌 1
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West African–South American pandemic Vibrio cholerae encodes multiple distinct phage defence systems - Nature Microbiology The West African–South American lineage of Vibrio cholerae contains multiple distinct anti-phage defence systems that provide resistance to various phage families, including vibriophage ICP1, a key pr...

Exciting news!! Our latest paper is out in Nat. Microbiol. @natmicrobiol.nature.com

We show that a sub-lineage of 7th pandemic V. cholerae has acquired mobile genetic elements packed with phage defense systems—rendering it multi-phage resistant 😳 ..... 1/3

www.nature.com/articles/s41...

22.05.2025 18:14 — 👍 196    🔁 69    💬 8    📌 1

✨ Still excellent ✨
@ceplas.bsky.social ✅

22.05.2025 16:07 — 👍 17    🔁 1    💬 0    📌 0