Neil Rajan

Selena Gomez has shared her experiences living with #lupus since 2015 - writes Foundation-funded researcher @bcellsrosser.bsky.social for @uk.theconversation.com.

To learn more, you can meet Dr Lizzy Rosser at our New Scientist Live stand (C20) on 18-19 October! shorturl.at/BusFG

Spatial architecture of development and disease - Nature Reviews Genetics Spatial omics has empowered the discovery of developmental and disease-associated molecular signatures, cell states and multicellular niches, as well as the evaluation of disease heterogeneity within and across organs. The authors review spatially resolved molecular changes across diseases and discuss the potential of spatial multi-omics for clinical applications, including the recent impact of artificial intelligence.

Review | Spatial architecture of development and disease www.nature.com/articles/s41...

A photo of a Nobel medal

BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance"

Stay tuned for more.
#NobelPrize

We're delighted to see immunologists once again recognised by the #NobelPrize! 🏆

Warm congratulations to the winners - their contributions have been vital in shaping our understanding of the immune system.

More here: www.immunology.org/news/british...

Liverpool skyline%2C plenary session ' Immunology in the balance'

📅 Wed 3 Dec | Immunology in the balance with Prof. Lydia Lynch

How does the immune system walk the line between protection & pathology? Join this session on the regulation of innate & adaptive immunity in infection, cancer, and inflammatory disease.

#Immunology #BSI25

Rocking it!

Dermatology joins GeNotes as 12th specialty - Genomics Education Programme New dermatology collection covers a wide range of clinical scenarios, underpinned by extended opportunities for learning Dermatology professionals now have access to a fantastic new set of useful reso...

www.genomicseducation.hee.nhs.uk/news/dermato...

Calling all #dermatologists! We've just launched our new #GeNotes collection of resources to support you in accessing #GenomicTesting for your patients. Developed by Dr fellow dermatology experts, this is one not to miss!

Great work Christoph 👏🏾

IL-18 in atopic dermatitis—a multifaceted driver of skin inflammation Atopic dermatitis (AD) is a common chronic inflammatory skin disease characterized by pruritus, barrier dysfunction, and immune cell infiltration. Despite significant progress in our understanding of ...

🚀 Excited to share our new Review in @jacionline.bsky.social !
We summarize the current evidence on IL-18 in atopic dermatitis.

📊 Links to barrier dysfunction & disease severity
💡 Potential biomarker & therapeutic target

Read here 👉 www.jacionline.org/article/S009...

#IL18 #atopicdermatitis

We’re thrilled to introduce our four official Social Media Ambassadors for the 54th Annual ESDR Meeting!

esdrmeeting.org/some2025/

@dr-hanat.bsky.social @dr-cganier.bsky.social @derm-scientist.bsky.social @drarmpit.bsky.social

Videos show pronuclear transfer, which was performed in a series of women with pathogenic mtDNA variants to reduce the transmission of these variants to their children. Read the full study about this method: nej.md/455eer6

#MedSky #Genetics

Cell-type-directed network-correcting combination therapy for Alzheimer’s disease A multi-cell-type drug discovery strategy targeting dysregulated gene networks in neurons and glia identified letrozole and irinotecan as a combination therapy that significantly improved memory and r...

The potential for 2 cancer drugs in combination to impact Alzheimer's disease as an outgrowth or single-cell RNA -seq, review of electronic health records from 1.4 million patients, and whittling down 1,300 potential repurposed drugs to 2.
www.cell.com/cell/fulltex...

The babies born with DNA from three parents – podcast Doctors in the UK have announced the birth of eight healthy babies after performing a groundbreaking procedure that creates IVF embryos with DNA from three people. Ian Sample tells Madeleine Finlay ab...

Amazing podcast on the mitochondrial donation babies. Great work by wonderful colleagues@mitonewcastle.bsky.social at @newcastleuni.bsky.social and the @lilyfoundation.bsky.social

www.theguardian.com/science/audi...

In vivo prime editing rescues alternating hemiplegia of childhood in mice Prime editing and base editing in mouse models and human cells effectively correct mutations in a gene that causes a childhood neurodevelopmental disorder called alternating hemiplegia of childhood. I...

One-shot prime genome editing ("CRISPR 3.0") of the brain in vivo corrected AHC, a rare genetic disorder, in the mouse model. Another big step forward in the genome editing field.
www.cell.com/cell/fulltex...

🍷 Save the Date! 🍷

Join us for an evening of wine tasting at the historic Trinity House in support of North East skin research.

🗓️ Friday 14th November 2025
📍 Trinity House, Newcastle
🎟️ All proceeds go directly to the North East Skin Research Fund

☀️ A fun Summer evening at The Magic Hat Cafe last night showcasing some of the fantastic skin research we have across the North East

✨ Thank you to everyone who attended and for supporting our North East Skin Research Fund

Sex differences in skin-cancer risk are linked to oestrogen levels Premenopausal women are more likely than men to develop certain cancers. Pathways activated by the sex hormone responsible could be targeted in cancer therapies.

Premenopausal women are more likely than men to develop certain cancers. Pathways activated by the sex hormone responsible could be targeted in cancer therapies

https://go.nature.com/445tJ0u

Incredible opening keynote by Charlie Swanton - spanning tumour initiation, aging, environmental exposure and much more 👏👏

#EACR2025
@charlesswanton.bsky.social
@crick.ac.uk
@helloeacr.bsky.social

Transparent peer review to be extended to all of Nature’s research papers From today, all new submissions to Nature that are published will be accompanied by referees’ reports and author responses — to illuminate the process of producing rigorous science.

From today, all new submissions to Nature that are published will be accompanied by referees’ reports and author responses — to illuminate the process of producing rigorous science

https://go.nature.com/4kIRR01

Welcome @northeastskin.bsky.social 😄

👋 Hello Bluesky! 🦋 We are the North East Skin Research Fund - bringing you the latest updates on skin research led by dermatologists and academics here in the North East of England! 🧴🧪

📸 Featuring our new logo

#NESRF #northeastskin #northeast #northeastengland #skinresearch #dermatology

Cutaneous Fibrofolliculomas and Trichodiscomas in... : Dermatologic Surgery developing recommendations for surgical treatment. METHODS A literature search was conducted to review cases of BHD associated fibrofolliculomas and trichodiscomas and the role of cryosurgery, cure...

“Cutaneous fibrofolliculomas and trichodiscomas in Birt-Hogg-Dubé syndrome: a review of therapeutic strategies” is now out in Dermatological Surgery! 🎉 journals.lww.com/dermatologic...

A real testament to the BHD patient advocates and @derm-scientist.bsky.social who have championed this work!

Great work William 👏🏾

Review Article: Cell Therapy and the #Skin: Great Potential but in Need of Optimization.
Lee et al
doi.org/10.1016/j.ji...
#DermatologyJournal #dermatology #dermsky #dermatologists #dermresearch #dermscience #dermatologyresearch

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease | NEJM Base editors can correct disease-causing genetic variants. After a neonate had received a diagnosis of severe carbamoyl-phosphate synthetase 1 deficiency, a disease with an estimated 50% mortality ...

A lipid nanoparticle–delivered base-editing therapy was custom designed for an infant with a ureacycle disorder. The affected infant was treated at approximately 7 and 8 months of age. Read the Brief Report: nej.md/42XF03F

#ASGCT2025 #MedSky @asgct.bsky.social

Become a Social Media Ambassador for the 54th Annual @esdrorg.bsky.social ESDR Meeting! is a fantastic opportunity to contribute to the success of the meeting while building your professional network and showcasing your creativity. Apply Now! esdr.org/y-esdr/socia...

We are delighted to introduce the recipients of the 2025 ISID Collegiality Awards.
This year’s awardees Longlong Luo and Irene García Jiménez will be formally honored during the award ceremony at the SID 2025 Meeting in San Diego.

Celebrating 20 Years of the International Pachyonychia Congenita Consortium.
Read Coulombe et al's News & Perspective Commentary in the April issue.
doi.org/10.1016/j.ji...
#DermatologyJournal #dermatology #dermsky #dermatologists #dermresearch #dermscience #dermatologyresearch

The amazing Prof Chris Stewart @stewartlab.bsky.social gives his inaugural lecture👏🏾👏🏾👏🏾

Now that's a cool collab!