Antoine Madar

Behavioral Timescale Synaptic Plasticity: A Burst in the Field of Learning and Memory Hebbian synaptic plasticity is currently the main framework to relate neuronal activity, network structure, and learning and memory. However, recent experimental and computational modeling studies hav...

We also have a review out in JNeuro on the topic with @neurosutras.bsky.social, Tom O'Dell, Anant Jain, @clopathlab.bsky.social and Mark Sheffield.
Physical copies available at @sfnjournals.bsky.social booth.
www.jneurosci.org/content/45/4...

If you're at SfN and interested in Behavioral Timescale Plasticity, dendritic plateaus or mechanisms for learning and memory, consider coming to our minisymposium on BTSP tomorrow morning: eppro02.ativ.me/appinfo.php?... #SfN25

q.e.d Science Critical Thinking AI for constructive criticism and science evaluation

Here's the link to the system, try it! qedscience.com
@qedscience.bsky.social

Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com

*Please repost* @sjgreenwood.bsky.social and I just launched a new personalized feed (*please pin*) that we hope will become a "must use" for #academicsky. The feed shows posts about papers filtered by *your* follower network. It's become my default Bluesky experience bsky.app/profile/pape...

Hippocampal pyramidal cells of the CA1 region are not a major target of the thalamic nucleus reuniens Excitatory input from the prefrontal cortex to hippocampus pyramidal cells is commonly believed to be mediated through the thalamic nucleus reuniens brain region. This study shows in rodents that this...

Delighted that our main #TeamReuniens paper is finally out in @plosbiology.org. Been a long time in the making, congratulations to Lilya and all the team. A thread to follow soon, after I've had some sleep... #NeuroSkyence

journals.plos.org/plosbiology/...

First author Ramanujan Srinath demonstrated some of the things that make him a great scientist: he thinks deeply & creatively, brings together many forms of evidence & people, and is determined and innovative. He is on the job market this year and will run an incredible lab – don’t miss out! 5/

Not too early to get excited about presenting in San Diego in November! A minisymposium on BTSP organized by @antoinemadar.bsky.social
www.sfn.org/meetings/neu...

Opinion | What RFK Jr. Got Right About Academic Publishing The system no longer works for anyone except corporate publishers.

A broken clock gives the right time twice a day... A call for Universities to stop feeding the publishing industries 40% margins and build a global university consortium taking charge of academic publishing (by R Kaplan, former associate director of NIH)
www.chronicle.com/article/what...

Congrats Hannah! This looks awesome, can't wait to dig in.

ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.

Today NIH staff sent a letter to the NIH Director voicing their concerns over the impact of recent actions on biomedical research, and urging him to reverse the disruptive NIH policy changes and restore NIH grants that have been cut or delayed. Add your signature. actionnetwork.org/forms/add-na...

Learning in living mice defies classic synaptic plasticity rule Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment…

In a recent study, @antoinemadar.bsky.social & Mark Sheffield looked at place cells of the mouse hippocampus in vivo to understand what plasticity rules support learning—spoiler alert, it wasn’t Hebbian plasticity! Go check out my story for @thetransmitter.bsky.social

#neuroskyence 🧪

"My instinctive reaction was to withhold this case from publication. The patient was my only sister."

An incredible article (still guarded behind a paywall by Oxford University Press, 90 years after publication)

A chocolate cake with red and white decorations and lit candles shaped as the number 75. Bold text reads: ‘The NSF Turns 75 Today. What has it done over the past 7 decades?’ The background is a celebratory red with a spray-paint texture.

HAPPY 75th, NSF!

We’re celebrating this milestone by highlighting some of NSF’s most transformative accomplishments—innovations that have shaped our world and continue to drive progress in health, technology, the environment, and beyond.

Read on 🧵(1/11):

Here is a specific thing you can do to fight Trump's politicization of public services Plus: what I wrote in Science about the revised Schedule F

New from me: Everything feels overwhelming. But here is a tangible thing you can do: write a comment to oppose Trump's plan to convert 50,000 career civil servants into political appointees. Deadline is May 23. Please share!
donmoynihan.substack.com/p/here-is-a-...

How do cognitive maps fail? And how can this help us understand/treat psychosis? My lab at @oxexppsy.bsky.social is hiring a Postdoc tinyurl.com/2p935hhz and RA tinyurl.com/3myfpb78 to answer these questions in mouse models.
Here's why you might want to join: 🧵

A metabolic function of the hippocampal sharp wave-ripple - Nature Sharp wave-ripples from the hippocampus are shown to modulate peripheral glucose homeostasis in rats, offering insights into the mechanism that links sleep disruption and blood glucose regulation in t...

many good comments on the role of astrocytes, neurovascular coupling in blood flow regulation... But links between brain activity and metabolism are complex and surprising sometimes. See for instance that very cool and out-of-the-box study by @davidtingley.bsky.social www.nature.com/articles/s41...

Turns out, saving science costs money.

Please consider supporting our fight with a donation to @standupforscience.bsky.social.

Every. Single. Dollar. Counts. (really!)

Home - National Tax Strike We’re fighting this constitutional crisis. Say NO to unchecked powers, NO to corrupt leadership, and NO to dismantling the federal government! What is the National Tax Strike? A movement to STOP payin...

You can join the Tax Strike at anytime, not just during tax filing season. If you're a W4 employee, retiree, or self-employed, you can change your withholding now and delay your decision to pay federal income taxes. It's time to take back our power. Join us today: Taxstrike.info

Tax Day is a reminder that there is strength in numbers. This administration is using our money to takeover our government - and WE have the power to stop them. We will not allow our tax dollars to be used to undermine the Constitution, disappear our neighbors, or destroy our institutions.

Home - National Tax Strike We’re fighting this constitutional crisis. Say NO to unchecked powers, NO to corrupt leadership, and NO to dismantling the federal government! What is the National Tax Strike? A movement to STOP payin...

Tax day today. Or is it? Not paying taxes is a historical and fundamental tool to resist. #taxstrike @nationaltaxstrike.bsky.social taxstrike.info

Public protests are important for solidarity & signaling. But the real work having impact right now is in the courts. So if you've attended protests and are thinking 'what's next?' here are some legal funds to donate to:
statedemocracydefenders.org/fund/
democracyforward.org
ldad.org/letters-briefs

Cardboard sign that says "stop doing illegal things"

Guys it's a reasonable ask #handsoff2025

US map via scienceimpacts.org visualization of economic loss due to IDC cuts to 15% as part of Feb 7, 2025 executive order, with shading denoting intensity of cuts.

Working with an interdisciplinary team, we have developed a website to communicate how the White House's proposed cuts to health research would cause losses of $16B and 68,500 jobs.

Find out how your community may be impacted.

Explore more at SCIMaP: scienceimpacts.org

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Excited to share our latest story! We found disentangled memory representations in the hippocampus that generalized across time and environments, despite the seemingly random drift and remapping of single cells. This code enabled the transfer of prior knowledge to solve new tasks

Want to know what synaptic plasticity rules operate in-vivo to support learning? Read our new paper, combining computational modeling and analysis of place field trajectories during familiarization to novel environments.
#BTSP #STDP #hippocampus #CA1 #CA3
#FirstBlueskyTweet