Jaroslav Icha

Acquifer HIVE: The Next Generation of Big Data Management for Microscopy This Bruker webinar introduces the Acquifer HIVE, a centralized data storage and computing solution for processing, analyzing, and visualizing scientific data.

The HIVE underwent quite some upgrades so we are running a webinar to introduce them. If big microscopy data is something you are dealing with, do consider joining. 👇
www.bruker.com/en/news-and-...

One of the Bruker FM products I sell to light microscopists is a server for image processing and storage, the HIVE.
>150 mainly imaging facilities over the years thought it is a good idea to get a HIVE and I'm sure they still do. Even the first installs now 10 years old are mostly still running.

But jokes aside, this will be a condensed value proposition directly from my colleague who is building these. So if big data is something you are dealing with, I recommend to join and get all the info and insights first hand.

I talked about this server for image processing and storage to all microscopists that were willing to listen (also to those not refusing too actively).
HIVE underwent an upgrade for next generation hardware. So it is time for everyone's favorite pastime activity...a webinar! goto.bruker.com/4aCYm0J

Featured image with Jan Martinek - FocalPlane Featured image with Jan Martinek - News

focalplane.biologists.com/2026/02/13/f...

For whoever going to BonnBrain in March, consider extending your stay by one day and participate in our hands-on! workshop.
Imaging neuronal activity with Inscopix 2P miniscope and voltage imaging with the Ultima 2P Plus multiphoton microscope.
www.bruker.com/en/news-and-...

Expansion Microscopy Has Transformed How We See the Cellular World | Quanta Magazine How physically magnifying objects using a key ingredient in diapers has opened an unprecedented view of the microbial world.

Eye candy: article about expansion microscopy of protists.
www.quantamagazine.org/expansion-mi...
Unicellular eukaryotic diversity is often overlooked but I'm thankful it was part of curriculum during my undergrad in Prague. There is exciting and weird cell biology going on in different protists.

1/10 New preprint on bioRxiv
Nanodiamonds for spatial resolution benchmarking in two-photon microscopy

We introduce nanodiamond-based phantoms as a robust, reusable alternative to bead–agarose samples for PSF calibration.

www.biorxiv.org/content/10.6...

Deadline for abstract submission in one week!

I'm sharing this reminder because right after the conference we have an open demo day at DZNE Bonn, which will include voltage imaging on Bruker 2P microscope and Ca imaging in freely moving mice with Inscopix miniscopes
www.bruker.com/en/news-and-...

We are hosting a demo day for @brukercorporation.bsky.social two photon microscopes and Inscopix miniscopes.
📅 March 26th 2026
📌 DZNE in Bonn
Whole day event with hands on sessions, presentations and discussions with our existing 2P users.

Register: www.bruker.com/en/news-and-...

We are hosting a demo day for @brukercorporation.bsky.social two photon microscopes and Inscopix miniscopes.
📅 March 26th 2026
📌 DZNE in Bonn
Whole day event with hands on sessions, presentations and discussions with our existing 2P users.

Register: www.bruker.com/en/news-and-...

We (Bruker Fluorescence Microscopy) will run a satellite event on March 26th. A mixture of a hands on demo of our 2P and miniscopes and our user meeting.
One can attend independently of the conference, so this is a free event for anyone who can make a daytrip to Bonn.
www.bruker.com/en/news-and-...

First @brukercorporation.bsky.social (and mine) lightsheet microscope sale in Poland and it is straight away our most complex lattice system even with an IR laser photomanipulation module. Joint project with our distributor in Poland Labsoft.

Flyer advertising the BonnBrain Conference 2026, "From Genes to Circuits and Behavior".

Application is open! Come join us and our fantastic line-up of speakers next year in March in Bonn!

Flyer for the BonnBrain conference: Keynote lectures: Cori Bargmann, Edvard Moser, Maude Baldwin, Rosa Paolicelli, Zachary Knight Invited speakers: Inna Slutsky, Abhilasha Joshih, Dmitriy Aronov, Ruben Portugues, Laura Busse, Kishore Kuchibhotla, Long-Jun Wu, Rune Enger, Ania Majewska, Sarah Melzer, Carolina Rezaval, Josh Dudman Specials: Selected talks, young investigator symposium, posters, career session with Leonie Welberg from Nature Neuroscience & more

Join us for BonnBrain 2026!

The official deadline for abstract submission is December 15th, but we only have a few slots left and might be sold out before the deadline.

Apply quickly 👉 bonnbrain.de to be considered by our Scientific Committee!

Still looking for ptf1a promoter 🔍

I expect exciting results from this microscopein the next few years. The momentum in polish science is building up and they are entering the first world league (sadly, unlike the other V4 countries Czechia, Slovakia, Hungary, where I rather see stagnation; politics play a role).

The Luxendo InVi Lattice Pro is a good lattice system for imaging facilities like the one at the Nencki Institute because of its versatile sample mounting strategies and flexibility in configuration - lasers, cameras.

First @brukercorporation.bsky.social (and mine) lightsheet microscope sale in Poland and it is straight away our most complex lattice system even with an IR laser photomanipulation module. Joint project with our distributor in Poland Labsoft.

I meant to post it long time ago but things have been busy. Still, this article is worth sharing even if not breaking news.
Researchers at Tsinghua University developed a new approach to tissue clearing, VIVIT, using among other instruments, the Bruker MuVi SPIM
www.sciencedirect.com/science/arti...

The development of a single zebrafish retina captured on a light sheet microscope approx. every 12 hours from 1.5 days to 3.5 days after birth of the embryo. The retinal ganglion cells are labelled with Ath5:RFP (magenta) the amacrine and horizontal cells are labelled with Ptf1a:YFP (yellow) and the photoreceptors and bipolar cells are labelled with Crx:CFP (cyan). The image was created in the Norden lab at the MPI-CBG, Dresden. Credit text to Wikimedia Commons.

Development of the zebrafish retina captured on a light sheet microscope. Credit to @ichajaroslav.bsky.social. #ZebrafishZunday 🧪

Acquifer IM

Done on the Bruker FM Acquifer IM microscope: www.bruker.com/en/products-...

preprint: www.biorxiv.org/content/10.1...

Are you interested in long time lapse imaging of organoids?

In this example, retinal organoids were imaged in high throughput for 3 days. The aim was to collect sufficient data to be able to use machine learning for predicting organoid differentiation just from brightfield images.

🔥 It's Time ! #Mifobio2025

👉 imabio-cnrs.fr

#GDRImabio

@cnrs.fr
@cnrsingenierie.bsky.social
@cnrsbiologie.bsky.social

For those at Seeing is Believing in Heidelberg right now, do join our workshop, which is about to start soon at 11:30!
www.embl.org/about/info/c...
Focus on organoid time lapse imaging, with high throughput options as well.
#EESImaging

🚀 Our new paper is out @natmethods.nature.com!

Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.

🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/

✨🔬 #FluorescenceFriday
Confocal stack of chicken retina 🐥 — from inner nerve fibers up to photoreceptors.
Layer upon layer of mosaics, each cell type in its place.
Birds have remarkable visual systems, and under the microscope, they look absolutely stunning in detail.

The #SCZI2026 Oral Abstract and Workshop proposal deadline has been extended! They are now due September 24th at 11:59pm EDT. Register and Submit here: www.izfs.org/education/11...

We have just installed a third HIVE server in Czechia. After Prague and Brno, we are adding Olomouc!
www.bruker.com/de/products-...
Researchers often get HIVE to handle data from Luxendo as well as other companies' light-sheet scopes but it is a rather universal solution for big data management.

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)