Huge thanks to @hantan98.bsky.social for completing the work started by Andrew and Robyn many moons ago!! Many thanks also to CHDI for funding!
27.06.2025 07:40 — 👍 2 🔁 0 💬 0 📌 0Huge thanks to @hantan98.bsky.social for completing the work started by Andrew and Robyn many moons ago!! Many thanks also to CHDI for funding!
27.06.2025 07:40 — 👍 2 🔁 0 💬 0 📌 0Excess ADBE was conserved across all cell types examined and intriguingly was due to huntingtin haploinsufficiency, rather than a toxic gain of function of mutant huntingtin.
27.06.2025 07:38 — 👍 1 🔁 0 💬 1 📌 0• We are delighted to contribute to this work just out in @jneurochem.bsky.social, where we collaborate with the BlueSkyless Smillie lab to reveal that Huntington’s Disease model neurons display excess activity-dependent bulk endocytosis (ADBE).
27.06.2025 07:38 — 👍 4 🔁 5 💬 1 📌 0
ISN is seeking volunteers for its committees!
This is a great opportunity to contribute, connect, and help lead our global community.
🗓️ Apply by June 29
📨 Email: secretariat@neurochemistry.org with a short bio and brief statement on why you’re applying.
#WeAreNeurochemistry #neurosky
Fantastic effort from the Presynaptic Pacers, covering the slow leg from an old PI in their team at the Hairy Haggis relay!! All done to support @epilepsyinst.bsky.social!
25.05.2025 15:13 — 👍 6 🔁 2 💬 0 📌 0
Huge thanks to James, Jess, Zita and Angus for manning the @mmecepilepsy.bsky.social table today at the CDBS friends and family day! Great to spread the word about the amazing work the Centre is doing!
16.05.2025 15:36 — 👍 0 🔁 0 💬 0 📌 0Great work Sam!!
08.05.2025 07:42 — 👍 0 🔁 0 💬 0 📌 0
What, what! We just published our work studying GABAB receptors in human and rat brain.
www.nature.com/articles/s41...
All funds raised go to @epilepsyinst.bsky.social !!
05.05.2025 16:03 — 👍 2 🔁 0 💬 0 📌 0
At the end of the month, The Presynaptic Pacers - a team of epilepsy researchers from the Cousin Lab - are running the Edinburgh Hairy Haggis Relay (May 25th) to raise funds for the Epilepsy Research Institute. Support our run and help drive life-changing research: shorturl.at/hUPhh
05.05.2025 16:01 — 👍 5 🔁 4 💬 0 📌 1
At the end of the month, The Presynaptic Pacers - a team of epilepsy researchers from the Cousin Lab - are running the Edinburgh Hairy Haggis Relay (May 25th) to raise funds for the Epilepsy Research Institute. Support our run and help drive life-changing research: shorturl.at/hUPhh
05.05.2025 16:01 — 👍 5 🔁 4 💬 0 📌 1
Excited for our latest work! We developed nanobinders for the luminal domain of Synaptotagmin 1 (calcium sensor for synaptic vesicles). Thanks among others to @verstrekenlab.bsky.social @opazo.bsky.social @meunierlab.bsky.social @volkerhaucke-lab.bsky.social www.biorxiv.org/content/10.1...
22.04.2025 09:27 — 👍 23 🔁 19 💬 2 📌 3This would not have been possible without the heroic effort of Dr. Katherine Bonnycastle who invested years in this long-term project! Thanks also to Sarfaraz for the blots!
17.04.2025 15:44 — 👍 2 🔁 0 💬 0 📌 0These models have mutations in genes exclusive to either the pre- or postsynapse, suggesting ADBE is a presynaptic homeostatic mechanism that corrects for intrinsic dysfunction in ASD neurons.
17.04.2025 15:44 — 👍 4 🔁 0 💬 0 📌 1Our latest paper is out in Molecular Autism! We reveal that in neurons from five independent rat models of monogenic Autism Spectrum Disorder (ASD), activity-dependent endocytosis (ADBE) is selectively depressed, with no other synaptic vesicle recycling phenotype. Link to paper - rdcu.be/eh4Qa
17.04.2025 15:43 — 👍 3 🔁 0 💬 0 📌 1
🎉 Congrats to Sabrin Haddad - winner of the 2024 JNC Young Scientist Paper of the Year Award (in honor of Mark A. Smith)!
Her paper reveals how a CACNA2D2 mutation disrupts calcium channel & synaptic function in encephalopathy.
🔗Read here: bit.ly/3EjpeXq
#WeAreNeurochemistry #YoungScientistAward
Edinburgh castle in the distance all lit up in purple
No sign of the aurora but at least I got to see the castle lit in purple for #epilepsy #PurpleDay ❤️
26.03.2025 20:27 — 👍 25 🔁 2 💬 1 📌 0
graphic: growth of person and brain
It's #PurpleDay: a day to increase awareness of #epilepsy. Hannah, a 1st year PhD @edinuni-irr.bsky.social, has written about the need to investigate the neurodevelopmental consequences of early-onset epilepsy and risk factors contributing to them: edin.ac/4j6PMKh
26.03.2025 12:14 — 👍 2 🔁 1 💬 0 📌 0
Happy Purple Day from us to the whole epilepsy community 💜! #PurpleDay2025
26.03.2025 10:12 — 👍 2 🔁 1 💬 0 📌 0
Job Opportunity at JNC!✍️
The Journal of Neurochemistry is looking for a Freelance Editorial Assistant! If you have a background in science and publishing, this is your chance to join a global research community.
✅ Remote & flexible
✅ Support publishing
✅ Global network
🔗Apply here: bit.ly/3FAs1M6
We are looking for motivated post docs. Projects on Alzheimer’s and Synucleinopathy. New mouse models, combined lightsheet/15.2T MRI and high throughput cognitive testing using touchscreens. Perfect for a recent graduate in Neurosciences or related field. Come work with us in 🇨🇦 👊😀🧪 please share.
05.02.2025 01:53 — 👍 33 🔁 20 💬 1 📌 4Come and join our @epilepsyinst.bsky.social Doctoral Training Centre. Are you bright and passionate about epilepsy research? Want to join a nurturing and exciting programme? We have space for one more exceptional student. For details see www.muirmaxwellcentre.com/doctoral-tra...
07.02.2025 14:43 — 👍 3 🔁 1 💬 0 📌 0We're happy to announce the launch of the new website of the Club Exo-endo. From the site, you can register for the annual meeting, register as a new member, advertise a position, apply for the thesis prize or post your latest publication. Please visit us at exoendo.org and make it interactive !
06.02.2025 20:26 — 👍 9 🔁 10 💬 0 📌 0
The Donlin-Asp Lab ( @pdaphd.bsky.social ) is hiring a postdoc to conduct primary research into how neurons transport mRNA to distal sites and use these mRNAs as substrates for local protein synthesis during synaptic plasticity.
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
@edinunineuro.bsky.social
New review out from our lab on SV2A! Thanks to James for all his hard work on this!
28.01.2025 17:12 — 👍 5 🔁 5 💬 0 📌 0Christen was an excellent scientist who made considerable contributions to the endocytosis field. I always enjoyed our interactions and he is very sadly missed.
03.12.2024 17:48 — 👍 2 🔁 0 💬 0 📌 0
🌟 ISN Membership 2025 is Open!
Join or renew today to unlock:
✅ Discounted ISN meeting registration fees
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✅ Free online access to JNC
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Be part of the global neurochemistry community 👉 ow.ly/jf1250UjGWA
#WeAreNeurochemistry #neuroskyence
Great to be here @prinetti.bsky.social! #WeAreNeurochemistry!
29.11.2024 13:40 — 👍 0 🔁 0 💬 0 📌 0@thecousinlab.bsky.social have just joined BlueSky, please feel free to follow to keep up with all things presynaptic!
29.11.2024 12:25 — 👍 4 🔁 0 💬 2 📌 0