Really pleased to see this study led by @raymondkiu.bsky.social now published in @natcomms.nature.com!
We show that probiotics help modulate the preterm infant πΆ#microbiome - to reduce ARGs, lower MDR bacteria π¦ & increase beneficial Bifido β¨
Huge team effort!
www.nature.com/articles/s41...
17.08.2025 23:54 β π 54 π 26 π¬ 0 π 0
HPV vaccination: How the world can eliminate cervical cancer
HPV vaccines offer a rare opportunity to effectively eliminate one type of cancer. By taking this opportunity, itβs possible to save hundreds of thousands of women eachΒ year.
Some positive stories ππΎ
βCountries with widespread HPV vaccination and regular cervical cancer screenings are already seeing dramatic reductions in cancer rates. They demonstrate that itβs possible to effectively eliminate the diseaseβ
@scientificdiscovery.dev
ourworldindata.org/hpv-vaccinat...
12.08.2025 02:30 β π 109 π 35 π¬ 2 π 5
Here is another map of malaria from 1870
ourworldindata.org/malaria
12.08.2025 16:32 β π 5 π 3 π¬ 0 π 0
By βreturn,β what is meant is that malaria was once endemic in the US. The CDC was founded in Georgiaβbecause it was then the nationβs malaria hotspot. Hereβs a Library of Congress map showing past distribution:
www.loc.gov/resource/g37...
12.08.2025 16:32 β π 7 π 5 π¬ 1 π 0
We are investigating possible locally acquired case of malaria - Tacoma-Pierce County Health Department
The risk to the public is very low. An East Pierce County woman who has not traveled recently was diagnosed Aug. 2 with malaria.
In the past 2 years, the US has reported a return of locally acquired malaria. In 2023, Florida & Texas reported P. vivax, then Maryland reported P. falciparum. Now, as far north as Pierce County, WA, a potential local case is under investigation (species TBD).
tpchd.org/news/we-are-...
12.08.2025 16:27 β π 9 π 9 π¬ 1 π 0
Panels one and two:
Two white mice make their way through a maze.
Panel three:
Having completed the maze, the two mice are rewarded with some fruit. Two scientists watch them. One says:
βPoor little things: all that thought and effort just to earn themselves a little treat.β
The second scientist looks at a clock and says: βCoffee time!β
Panels four and five:
The two scientists make their way through a maze of corridors to a door marked βCanteenβ
Panel six:
The scientists look at the food on offer. One says: βOoh, Donuts!β
My latest cartoon for @newscientist.com
11.08.2025 09:42 β π 3868 π 1080 π¬ 21 π 33
π§΅ Dengue is no longer just a tropical disease - it's showing up in Europe.
This season, France, Italy, and Portugal (Madeira) have already reported locally acquired dengue cases.
Check the latest #CDTR on #dengue here: bit.ly/3TQpDVu
#IdSky #EpiSky #MosquitoBorne #Prevention #PublicHealth
21.07.2025 14:33 β π 71 π 48 π¬ 2 π 6
Known effects of arginine on Gram-positive and Gram-negative behavior
It's seem like arginine is emerging as a major host cue. So we wrote an IAI minireview on how arginine levels vary between host tissues and affect microbial behavior.
The review is online today!
journals.asm.org/doi/epdf/10....
@brookeeryan3.bsky.social
#microsky
03.07.2025 16:07 β π 53 π 29 π¬ 1 π 1
Join us in Tubingen as a Junior Research Group Leader if you do research on #ESKAPE pathogens and infections and are interested in the highly cooperative environment of @dzif.bsky.social⬠and @cmfi.bsky.social ! Please send your application or forward to colleagues!
uni-tuebingen.de/universitaet...
19.05.2025 09:18 β π 35 π 64 π¬ 1 π 2
Wrong Jen Mitchell!
14.05.2025 10:43 β π 1 π 0 π¬ 0 π 0
Systemic inflammation impairs myelopoiesis and interferon type I responses in humans - Nature Immunology
Stunnenberg et al. use a model of lipopolysaccharide injection in humans to characterize the transcriptomic landscape of bone marrow and blood immune cells during the hyperinflammatory and immunosuppr...
#WeekendRead! #InterferonPower! Stunnenberg Pickkers Kox, Keramati &co show @natimmunol.bsky.org that 2 LPS injections in volunteers mimic the proinflammatory & immunosuppressive phases of #sepsis & found that IFNb treatment restores immune responsiveness in the suppressive phase!
10.05.2025 14:25 β π 30 π 10 π¬ 0 π 3
It's a 24 panel illustration, with a rotor (circle) with 24 open circles. For each increment from 1 to 24, an additional circle is filled with blue or pink, in ways that create a symmetrical axis of mass, allowing the rotor to be balanced when rotating at high speeds. The pinks generally show the odd numbers (divisible by 3) while the blues are the paired (divisible by 2) I think?
Weird intersection of math & centrifuge balancing:
Visual proof that it's possible to balance a 24-position centrifuge rotor for any number of equally-filled tubes EXCEPT 1 and 23.
Some of these are anxiety-inducing, though.
(π§βπ¨: aliyoh, labrats subreddit)
08.05.2025 13:09 β π 161 π 36 π¬ 15 π 2
The cellular mammalian clock regulates Staphylococcus aureus invasion in epithelial cells https://www.biorxiv.org/content/10.1101/2025.05.05.652254v1
07.05.2025 15:17 β π 2 π 2 π¬ 0 π 1
Current Scholarship Opportunities - UCD Graduate Studies
Interested in superbugs, AMR and stress resistance? Join us to do a PhD in the Corrigan lab
@UCDMedicine www.ucd.ie/graduatestud...
09.05.2025 10:40 β π 9 π 15 π¬ 1 π 0
Looking to appoint a new or experienced Postdoc to join my team. Investigating novel therapeutics targeting Crohn's disease associated bacteria. Background in Microbiology, Immunology, Biochemistry or related field. π¦ π¬
Apply here: my.corehr.com/pls/trrecrui...
Closing date: 31st May 2025
29.04.2025 16:24 β π 0 π 4 π¬ 0 π 1
Microbial Omics
A suite of bioinformatics tools for microbial genome and metagenome analysis.
I'm delighted to share a useful FREE web-based app portal of powerful bioinformatics tools for microbial genomes and shotgun microbiome sequences!
It's called Micromics and is built by Middle Author Bioinformatics, led by co-founder @ironark.bsky.social
omix.midauthorbio.com
08.04.2025 12:11 β π 178 π 74 π¬ 7 π 4
Why do we like vaccines and water systems so much?
It used to be 50/50 whether your kid lived to be an adult. With 4 kids, 94% chance they wouldn't all make it.
Fun times. Maybe let's not do that again.
We don't have magic cures for diseases like measles. We have vaccines.
09.04.2025 09:11 β π 758 π 239 π¬ 7 π 8
Molecular interplay between ComEC domains leads to efficient DNA translocation during natural transformation https://www.biorxiv.org/content/10.1101/2025.04.08.647572v1
09.04.2025 05:16 β π 2 π 1 π¬ 0 π 1
Staphylococcus aureus Bacteremia: A Review
This narrative review summarizes current evidence on the epidemiology, pathophysiology, clinical presentation, diagnosis, and treatment of Staphylococcus aureus bacteremia.
New review article on management of S. aureus bacteraemia: jamanetwork.com/journals/jam...
@jama.com @vancefowler.bsky.social #IDSky
Check out the gorgeous Figure which brings together elements of pathogenesis and management: (thread)
07.04.2025 15:52 β π 53 π 20 π¬ 2 π 4
Bifidobacteria support optimal infant vaccine responses - Nature
Neonatal antibiotic use is shown to reduce immune response to infant vaccines, accompanied by reduced abundance of Bifidobacteria in the gut microbiota, with experiments in mice indicating that probio...
Delighted our study (7+ years in the making) is out today in Nature. In a nutshell, 48 hours of antibiotics in week 1 led to impaired vaccine responses up to 15 months later in infants. We show (in-vivo) a probiotic can fix it #microbiome #science #immunology
www.nature.com/articles/s41...
02.04.2025 23:33 β π 135 π 58 π¬ 7 π 4
π€£
29.03.2025 15:04 β π 4 π 0 π¬ 5 π 0
In 3 days, the number of measles cases in a highly unvaccinated area of Texas has doubled. There are now 48 cases, all of whom are unvaccinated, and 13 of whom have been hospitalized so far, for a hospitalization rate of 27%. This is huge figure in epidemiology. This outbreak will keep spreading.
14.02.2025 20:05 β π 8590 π 3801 π¬ 530 π 403
Call for applications 2025 - Creation of new research groups at the Institut Pasteur - Research
The Institut Pasteur launches an international call to recruit new junior research group leaders in the application of cutting-edge transdisciplinary approaches to the exploration of host-microbe, tis...
π Join Institut Pasteur as a Junior Research Group Leader π
Explore host-microbe interactions in key areas like vaccinology, infectious diseases, neuro-immunology, and maternal health.
π
Deadline: Feb 28, 2025 (few weeks left!)
Apply now β¬οΈ
14.02.2025 08:55 β π 64 π 61 π¬ 0 π 0
Diabetes potentiates the emergence and expansion of antibiotic resistance
Diabetic infections are a reservoir for the emergence and proliferation of antibiotic resistance in Staphylococcus aureus.
Delighted to share our new study. A collaboration with the Thurlow lab. Antibiotic resistance rapidly emerges and thrives in diabetic mice. A worrying coming together of two major and growing health problems worldwide www.science.org/doi/10.1126/...
13.02.2025 11:48 β π 47 π 21 π¬ 1 π 1
PhD opportunity in bacterial pathogenesis- deadline tomorrow Feb 13 !
12.02.2025 13:12 β π 4 π 3 π¬ 1 π 0
Physicist exploring immunobiophysics through microscopy | B cells | mechanobiology | lymph nodes
@cnrs.fr research director, working @institutcochin.bsky.socialβ¬
Co-team leader of the DyCRIC team:
http://bit.ly/4mBy17l
https://pierobonlab.github.io/
Lapsed bioinformaticist. Dublin. Molecular Evolution and sequence alignment. Clustal. Current birder and not very good jazz guitarist. Ex TCD, EMBL, EBI, UCC and UCD.
Physician Scientist MDPhD
Infectious Diseases
Academic Medicine
Global Health
Science Communicator
Posts are my opinions, not my employer's and not medical advice
I bet on myself and double down
https://substack.com/@bktitanji
AP @BostonChildrens @harvardmed AM @broadinstitute
inflammation, tissue biology, quant.&systems immunology #1stGen #ImmigrantScientists #NewPI
SwimmingπββοΈ sewciophilicπ§΅microbial π§«biochemistπ§ͺπ§¬/biomaterials βοΈ scientist;
(bio)chemistry, materials and ecobiology of actinos/natural products;
microbiology/chemistry in hot tubs;
Biofilm Alliance;
Advisory Council member Microbiology Society;
She/her
Microbiologist & phage phanatic! Enthusiastic explorer of microbial genomes
PI at the Wadsworth Center, New York State Department of Health
Assist Prof @albany.edu
Currently obsessed with plasmid-dependent phage
www.wadsworth.org/research/laboratories/owen
Microbiologist with a love for difficult pathogens! Prof @ Uni of Warwick
Infectious diseases and their global story
Senior Lecturer @Queen's University Belfast, passionate about understanding the fascinating battle between intracellular pathogens & hosts and finding new antimicrobials to cure infections. #CellularMicrobiology, #Legionella. All views my own.
C. elegans, cilia, ciliopathies, CRISPR. Researcher/PI at University College Dublin, Ireland.
Biochemist | University College Dublin | Assist. Prof. School of Biomolecular and Biomedical Science | Group Leader at Systems Biology Ireland | Interests: Cancer Signalling Pathways; Malignant Melanoma; Drug Development | Opinions Mine.
Working on innate immunity & host-pathogen interactions. Finding new ways to treat infections by antibiotic resistant bacteria. All views are my own.
Pathogenic Mechanisms Research Group - University of Galway.
PI: Dr Aoife Boyd. Host-microbe interactions: pathogenic Vibrio bacteria. Marine aquaculture. Natural antimicrobial molecules. Microbes & venomous animals.
https://orcid.org/0000-0002-4631-9792
Host-Microbiome Interaction | Vaginal Microbiome | Preterm Birth | Functional Genomics
Trying to keep up with the literature. Infection, microbiome, bioinformatics and multi-omics.
Associate Professor in UCD T&L, Dublin National Teaching and Learning Research Fellow. Interest in inclusive, authentic and work-integrated assessment; programme and module design.
Assistant Professor in molecular microbiology - host-pathogen interactions, transcription, translation, signalling, and metabolism π§¬π¬π¦ (Trinity College Dublin)
BSc, MSc & PhD programmes spanning key areas of biomolecular & biomedical science;Biochemistry, Genetics, Microbiology, Neuroscience, Pharmacology, Biotechnology, Biotherapeutics, Infection Biology, Regulatory Affairs & Toxicology.
https://www.ucd.ie/sbbs
Assoc. Prof Microbiology UCD