Drawing of a cell showing mitochondria in the cytoplasm, with murine norovirus virions exiting the cell through damage to the plasma membrane. Image credit: Valerie Rodriguez Irizarry
Photo of Valerie Rodriguez Irizarry
Valerie Rodriguez Irizarry’s tour de force paper on murine norovirus adaptation/egress is now out in peer-reviewed form @plosbiology.org. It highlights the power of forward genetics in virology research. 🧵 1/10 journals.plos.org/plosbiology/...
25.06.2025 13:36 — 👍 32 🔁 13 💬 2 📌 0
For those interested, Mikayla elected to join UTSW Graduate school where I predict she will have an outstanding PhD!
27.05.2025 20:24 — 👍 2 🔁 0 💬 0 📌 0
Mikayla did all of this while part of the UT Southwestern-Postbaccalaureate to PhD (PB2PHD) Program. I highly recommend those that want to go to graduate school but need more experience (both bench and coursework) to consider PB2PHD! Thanks @ajdiazphd.bsky.social for leadership on the PB2PHD
27.05.2025 20:24 — 👍 2 🔁 0 💬 1 📌 0
We have found the MNV-HiBiT viruses excellent and faithful reporters of MNV replication. We highly recommend this system for its speed, fidelity, and robust readouts! We also have had great success generating other viruses with HiBiT insertions, so worth a try in your favorite virus as well.
27.05.2025 20:24 — 👍 1 🔁 0 💬 1 📌 0
Mikayla inserted the small HiBiT tag into the MNV genome. The HiBiT fragment can complement with the LgBiT fragment and form a functional nanoluciferase. She showed that this works in cell lysates and tissue lysates with great dynamic range and sensitivity. No need for engineered cell lines!
27.05.2025 20:24 — 👍 1 🔁 0 💬 1 📌 0
Excited to have this story published @plosbiology.org. We were surprised to find lipids are important for entry of a non-enveloped virus and that TMEM30a is important for enteric infection of murine norovirus!
23.04.2025 14:13 — 👍 7 🔁 3 💬 0 📌 0
Assistant Prof @ UTSW Biochemistry
Mechanisms of protein homeostasis in lipid metabolism
https://labs.utsouthwestern.edu/kober-lab
Scientist @MSKCC | We study dead cell clearance / phagocytosis | #Immunology | #CellBiology | #Metabolism | views my own, not MSKCC. FreeCon Signatory. Alaskan.
Viruses, metabolism, lipids, mass spec, herpes (both 🦠 and 🦎, but not reptile viruses).
Dynamics of Host-Pathogen Interactions Unit at @pasteur.fr https://research.pasteur.fr/en/team/dynamics-of-host-pathogen-interactions/
Virologist at UT Austin who works on host- pathogen interactions and RNA.
Professor of Medical Virology, University of Zurich, Switzerland.
My research group studies molecular mechanisms of the interferon system, interferon deficiencies, and viral disease.
Ph.D. Candidate in Julie Pfeiffer's lab at UTSW.
mexican in Germany with an open love for tacos
Associate Editor at #PLOSBiology for #openaccess, working with #microbiology and #immunology
https://scheduler.zoom.us/melissa-vazquez-hernandez/meet-the-editor-melissa
Views are my own
Associate professor at the university of Florida.
Father of two, lucky husband of fantastic scientist wife. In love with great food. Passionate for #viruses, #interferons, #enteroids, #organoids, #mucosalimmunity
Ph.D. Student @ UTSW Medical Center | Beckham Lab
We study antiviral immune responses of the intestinal epithelium, especially interferon lambda. We focus on how they are specialized for the gut, interactions with normal microbiota at homeostasis, and how they may go awry during inflammatory diseases.
A leading life science journal that champions high-impact research across all disciplines—from molecules to ecosystems. We offer innovative formats and collaborative editorial support to ensure your work achieves its full scientific impact.
Senior research scientist at the University of Texas Southwestern Medical Center (UTSW) in the Center for Alzheimer's and Neurodegenerative Diseases (CAND) in Dr. Marc Diamond's lab. Neuroscience, cell biology, microbiology, virology
Our labs study innate immune regulation during bacterial infection. We focus on interplay between mitochondria and Mycobacterium tuberculosis (Robbie Watson) and post-transcriptional control of macrophage activation (Kristin Patrick). Views are our own.
Molecular immunology lab at the University of Washington. Interests include innate immunity, host-virus interactions, RNA regulation, and genetics. All opinions are my own. Love photography
https://www.ramsavanlab.org/
https://seattle.cytokinesociety.org
#TCellsMakeYouSmart
This is my personal account where I will likely talk mostly about science… produced by us and others.
Associate Professor at Harvard Medical School, in love with a red-haired beautiful woman, his kids... and immunology. He/him/his. 🇮🇹 🇺🇸 Views my own.
From Sardinia to California - Professor at UCSD - Love microbes. Find me by the ocean or at my Pilates studio
Assistant Member/Professor, Lab Head @MSKCancerCenter. #PhysicianScientist #Immunologist. Views my own.
