Mattia Chini

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New preprint from the lab on synapse development in the nascent neocortical hierarchy!

Using mice that label MAGUK proteins developed by Seth Grant we find key differences in the laminar maturation of association and sensory motor cortices, including delayed, cortex-wide maturation of L1 synapses.

I’m very excited to announce that a part of my PhD thesis project is now a preprint! In this paper, we show how spontaneous activity prior to visual experience shapes neural circuits in the retina. (1/11)

Early rebalancing of neuroinflammatory cascades lastingly rescues prefrontal deficits in a 22q11.2ds model Cognitive deficits, a characteristic feature of neuropsychiatric disorders, reflect perturbed activity in neuronal networks. Increasing evidence has l…

Paper out in @brainbehavimm.bsky.social!
Big congrats to Anne who did all the hard work for this one 👏🎉

www.sciencedirect.com/science/arti...

Postdoc position in Paris: come help develop new generation human brain computer interfaces ⚡🧠💻

Interested? Contact me if you have experience with machine learning (e.g. simulation-based inference, RL, generative/diffusion models) or dynamical systems.

See below for + details and retweet 🙏

Yes, I agree. And I also think that many of the most commonly used ripple detection algorithms are pretty sloppy

That's why the question about detecting ripples is perhaps my favorite one in CON2PHYS. You'd think is a straightforward thing, and yet..

So much ammo to get what they're missing too! The glorious times of Killian Hayes are long gone 😓

congrats Pierre!

A prefrontal cortex map based on single-neuron activity - Nature Neuroscience The authors mapped spontaneous and choice activity across mouse prefrontal cortex. The activity maps aligned with intrinsic connectivity rather than anatomical subregions, suggesting that connectivity...

Main postdoc study out! We can redefine prefrontal cortex regions with single-unit activity! Grateful to @carlenlab.bsky.social and @weltgeischt.bsky.social who made this crazy project real. Thanks to all co-authors, collaborators, and reviewers.
www.nature.com/articles/s41...

2 days left to register for the Pre-COSYNE Brainhack 2026 in Lisbon!
A great opportunity to meet the community working on research software, while collaborating on reproducible analyses in systems neuroscience.

main goal for this year: find a new job! 🙂

looking for a role with fun & complex technical challenges & within a great community. my main expertise is in signal processing/EEG/MEG, but topic-wise I am quite flexible.

science/industry both great! starting mid-year. nschawor.github.io/cv

get in before the spots run out, otherwise put your money in the betting pool

The Pre-COSYNE Brainhack 2026 Everything you need to know about the Pre-COSYNE Brainhack 2026 in Lisbon, Portugal.

This year’s Brainhack draws inspiration from CON²PHYS: same dataset, same questions, many truths? Expect hacking sessions, mini-presentations, discussions on reproducibility and a welcoming environment for all skill levels. Apply now (limited spots): pre-cosyne-brainhack.github.io/hackathon202...

Pre-COSYNE Brainhack 2026 The 2026 edition of the Pre-COSYNE Brainhack in Lisbon, Portugal.

Pre-COSYNE Brainhack 2026 – Join Us in Lisbon!
March 10–11, 2026 • Lisbon, Portugal

pre-cosyne-brainhack.github.io/hackathon2026/

Kick off COSYNE week with two days of hands-on, team-based hacking around real electrophysiology data, open tools, and reproducible workflows. #brainhack #cosyne2026

Feisty male deers.. sounds like a dangerous vacation!

🚨This was not supposed to be a Friday news dump.
Come join us at the pre-COSYNE hackathon!

And if can’t make it to the hackathon, don’t overthink it. Start working on the full CON2PHYS project: mchini.github.io/con2phys/

Remember that submissions will be eligible for co-authorship!

By the way, if you’re interested in working together on problems like this, I’m starting my lab at UCSF this summer. Get in touch if you’re interested in doing a postdoc! More info here: wj2.github.io/postdoc_ad (7/7)

📣 Pre-COSYNE Brainhack 2026 – Join Us in Lisbon! 🧠✨
March 10–11, 2026 • Lisbon, Portugal

pre-cosyne-brainhack.github.io/hackathon2026

Kick off COSYNE week with two days of hands-on, team-based hacking around real electrophysiology data!

✅ Apply now via the event website (limited spots).

Registration Deadline: Sunday, January 18 at 5:00 PM (London time). Notification: We will notify applicants of the outcome by the end of January.

We're excited for the Pre-COSYNE 2026 Brainhack! March 10–11 in Lisbon 🇵🇹

We'll be using CON²PHYS: same dataset, same questions, many truths?

🔹2 days
🔹team-based
🔹real ephys data
🔹open tools
🔹mini-presentations
🔹all skill levels

Apply now! 👇👇👇
pre-cosyne-brainhack.github.io/hackathon202...

This ⬇️

are you looking for someone with expertise in analysis of neuroimaging data (fMRI/DTI/EEG)? see ⬇️

What is a 🧠 ripple? See our @cellpress.bsky.social perspective on ripple diversity and the grammar of memory replay: connecting key pieces from current work across the field. 👉🏼 www.sciencedirect.com:5037/science/arti...

Very impressive work 🔥
Both technically (longitudinal 2p in neonatal mice requires a bit of insanity 😂) and computationally (the brain grows a lot in a week!).
❤️ the open access data too!

You were far too kind with that mediocre paper!

And ❤️ for the use of oligarchy

So also the brain read "Antifragile"? 🤔
And congrats on the paper, this looks amazing!

🚨new work with the dream team @danakarca.bsky.social @loopyluppi.bsky.social @fatemehhadaeghi.bsky.social @stuartoldham.bsky.social @duncanastle.bsky.social
We use game theory and show the brain is not optimally wired for communication and there’s more to its story:
www.biorxiv.org/content/10.6...

Finally got the job ad—looking for 2 PhD students to start spring next year:

www.gao-unit.com/join-us/

If comp neuro, ML, and AI4Neuro is your thing, or you just nerd out over brain recordings, apply!

I'm at neurips. DM me here / on the conference app or email if you want to meet 🏖️🌮