That's such a lovely memory. May all your #ChemNobel predictions ring true to soften the day π but I am sure Prof Stoddard really admired Car and Parrinello π
08.10.2025 06:53 β π 2 π 0 π¬ 0 π 0@elisafadda.bsky.social
Associate Professor in the School of Biological Sciences at the University of Southampton, head chef at https://GlycoShape.org, Salem's butler, fucose fanatic #glycotime everyday! She/Her
That's such a lovely memory. May all your #ChemNobel predictions ring true to soften the day π but I am sure Prof Stoddard really admired Car and Parrinello π
08.10.2025 06:53 β π 2 π 0 π¬ 0 π 0A screenshot of text that reads: Fraser lived his life at a hundred miles an hour. But it wasn't always the best thing for him or for those closest to him. In an interview following the award of the Nobel Prize in 2016 he recalled his time growing up on a farm and said that that had instilled in him the work ethic of a honeybee. Nobody would doubt that he had that. He also talked about having the strength of a horse and the hide of an elephant; what he didn't mention is that he could also be as stubborn as a mule. He did things his way and was rarely persuaded to do otherwise. This bloody-mindedness undoubtedly contributed to his incredibly successful career. While those who didn't really know him will measure his contributions through the prizes he won, his real professional legacy is not those prizes, it is the people who passed through his lab and shared in his scientific journey. Yes, he changed science, but he changed lives too - including mine and many of those here today. I learned a lot from Fraser: some chemistry, how to make slides for presentations, how to always include a noun after the word 'this', and a few random Scottish words that I'm still not convinced he didn't just make up.
Itβs #chemnobel day. For me, and for quite a few other people who spent time in the Stoddart group, it will hit somewhat differently this year.
Seems the right time to share a couple of passages from the eulogy I gave at Fraserβs funeral earlier this year.
The proteasome-substrate-shuttle protein UBQLN2 containsβlike other quality control system proteinsβa long region devoid of lysine (a lysine desert)
Martin Grønbæk-Thygesen (from @rhp-lab.bsky.social) et al show that introducing K here causes ubiquitylation and degradation
doi.org/10.1101/2025...
I have been trying to get this published as an op-ed, but I am going to post it here since I think it is timely in light of the "consent" extortion events.
Deafening Quiet from the Scientific Establishment
jeremymberg.github.io/jeremyberg.g...
1/14
2/2 my personal favourite,
2) Anna Krylov and Jay Tanzman blog post about the pivotal contribution of cats to (quantum) chemistry:
hxstem.substack.com/p/chemistry-...
Happy reading! πΊπ π§ͺ
Tomorrow is #ChemNobel day!! π₯³π₯³ While we are all waiting eagerly for the announcement, my cat Salem suggest to you #chemsky friends some important reading to quench the nerves,
1) ACS important content: www.acs.org/pressroom/re...
And... 1/2 π§΅
Continuing my tour of books I should have already read, Calling Bullshit by @carlbergstrom.com and @jevinwest.bsky.social. Just a delight - an accessible, entertaining, insightful look at various forms of BS. Much like Weapons of Math Destruction, would love a 2025 update of this one.
07.10.2025 00:55 β π 363 π 70 π¬ 11 π 6The @natureportfolio.nature.com Collection celebrating the 2025 #NobelPrize in #Physics is now live!
07.10.2025 16:26 β π 9 π 6 π¬ 0 π 0Congrats to all!! Brilliant ππ»π₯³π₯³ππ»ππ»
07.10.2025 16:28 β π 1 π 0 π¬ 0 π 0Wow! This is magnificent #glycotime Anne! I thought only I could see hydrogen atoms!! πππ₯³π₯³
07.10.2025 16:28 β π 1 π 0 π¬ 0 π 0Neutrons are the best ... look at this histidine-galactose contact !! Our new neutron structure of lectin/gal is available as preprint in ChemRXiv chemrxiv.org/engage/chemr.... Thanks to @drmpblakeley.bsky.social @sebvidalchem.bsky.social and all colleagues for very fine collaboration
07.10.2025 14:07 β π 19 π 8 π¬ 2 π 2This sounds plausible to me. But if itβs true, it means that the age of social media might be over soon, with only the old and wrinkled (like myself) spending any actual time there.
07.10.2025 06:59 β π 52 π 24 π¬ 6 π 6This is fabulous #glycotime!! π Super congrats to you all! ππ»ππ»ππ»
07.10.2025 07:07 β π 1 π 0 π¬ 0 π 0Check our new venture into drug discovery #glycotime!
07.10.2025 06:11 β π 4 π 2 π¬ 0 π 0Polar stereographic map of 2-m temperature trends in units of Β°C per decade over the Arctic for the month of October. Trends are calculated over the 1979 to 2024 period using ERA5. The largest warming is an areas of open water that were previously sea ice covered along the Siberian side of the Arctic. These trends exceed 2Β°C/decade in these areas.
October has observed some of the largest warming trends in the #Arctic. This is greatest over areas with a lack of sea ice cover (nearly all of the Siberian Arctic). Arctic amplification is largest in the boreal fall.
Data: doi.org/10.24381/cds.... Info: doi.org/10.1175/BAMS....
Jane Goodall's last interview released: "Don't lose hope." Today's stories prove she was right.
Take a moment to listen to her words:
β¨daybreaknotesandbeans.substack.com/p/dont-lose-...
This β€΅οΈ is on my XMas/bday π wish list! πππ @princetonupress.bsky.social
press.princeton.edu/books/hardco...
π’πβοΈπ
π #Booksky
New blog post. In which I analyze the new HHMI announcement and what it means for the science publishing ecosystem openrxiv.org/preprint-man...
06.10.2025 18:53 β π 27 π 14 π¬ 0 π 3Screenshot of Avogadro2 using the interactive AutoOptimize tool to minimize a molecule (n-pentane) using the UFF force field. Text reads UFF ΞE = -229.80 kcal/mol
If you've been wondering about the status of the AutoOptimize interactive optimization in Avogadro2 - coming later this month π
06.10.2025 13:56 β π 11 π 2 π¬ 0 π 1The latest in a long series of Nobels for work in immunology - and it wonβt be the last (!)
06.10.2025 17:12 β π 55 π 14 π¬ 1 π 2Roberto Car and Michele Parrinello are on my #ChemNobel ballot for 2025 and for every year until they'll get it π
06.10.2025 17:09 β π 10 π 2 π¬ 0 π 0#NobelPrize week starts tomorrow & the #chemnobel is Wednesdayβ¦ used to be so much Nobel chat on Tw*tter, but that is not replicated here, alas. Anyway, for the record, I think MOFs will win at some point (maybe this year maybe not). Balasubramanian & Klenerman a good bet for next-gen sequencing too
05.10.2025 17:37 β π 112 π 19 π¬ 25 π 5Our Collection celebrating the 2025 Physiology or Medicine #NobelPrize is now live!
06.10.2025 16:10 β π 6 π 3 π¬ 0 π 0Lead by postdoc in the lab Ruiqi Ge and in collaboration with Bob Coffeyβs lab, we are happy to share rPAL-seq for rapid and sensitive sequencing based profiling of glycoRNAs @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
06.10.2025 13:36 β π 41 π 19 π¬ 1 π 4Diana Bianchi out at NICHHD. Hard to see a good reason for letting such a talented individual go www.science.org/content/arti...
06.10.2025 12:49 β π 10 π 7 π¬ 0 π 0Wow, this is a thing of beautyπ§ͺ ππ
06.10.2025 12:42 β π 7 π 1 π¬ 0 π 0Join us at lunchtime @imperialcollegeldn.bsky.social on Fri 24th Oct to discuss the past, present and future of socially responsible science.
www.imperial.ac.uk/events/19845...
"Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi made groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body"
Brilliant achievement ππ»ππ»ππ»ππ»ππ»ππ»π
www.nobelprize.org