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@labwyllie.bsky.social

29 Followers  |  47 Following  |  4 Posts  |  Joined: 03.04.2025  |  1.3006

Latest posts by labwyllie.bsky.social on Bluesky

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Antitrypanosomal quinazolines targeting lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease Quinazolines targeting Trypanosoma cruzi lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease.

Delighted our latest paper is now published in Science Translational Medicine. Fantastic collab with Dr Avninder Bhambra and his team. Our studies reveal promising quinazolines selectively target KRS in T. cruzi. www.science.org/doi/10.1126/...
@dundee.ac.uk

09.07.2025 19:06 — 👍 2    🔁 1    💬 0    📌 0
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Targeting de novo purine biosynthesis for tuberculosis treatment - Nature The validation of inhibitors targeting PurF, a novel drug target for tuberculosis drug discovery, is described.

Fantastic paper from MoA group alumni Richard Wall and colleagues 🙌 www.nature.com/articles/s41...

18.06.2025 16:13 — 👍 0    🔁 0    💬 0    📌 0
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The Thienopyrimidinone Gamhépathiopine Targets the QO Site of Plasmodium falciparum Cytochrome b Chemotherapy remains a key component of the arsenal of tools to fight malaria. Specifically, new drugs with diverse mechanism(s) of action are required to combat existing drug resistance. Here, we des...

New paper alert! Enjoy!
pubs.acs.org/doi/10.1021/...

11.06.2025 16:53 — 👍 1    🔁 1    💬 0    📌 0

Hello Blue-sky! Delighted to be on an inclusive and well run platform!

03.04.2025 19:07 — 👍 3    🔁 0    💬 1    📌 0

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