Imaging Center Campus Essen (ICCE)

Another #RDM4mic meeting, which focused on research data management for microscopy, took place
@uni-muenster.de. 💫
Several NFDI4BIOIMAGE task area leaders and data stewards met on site and contributed to the program.
Susanne Kunis' presentation is already available: doi.org/10.5281/zeno...

🏆 #LabOlympics 2025 at the ZMB are over — congratulations to the 'Ehrmännchen'! 🎉
They didn’t just take home the trophy, but also the honor of hosting the 2026 edition!
A big thanks to @hellerschmiedlab.bsky.social, @icce-unidue.bsky.social and all other participants for their amazing team spirit!

New work out by @hemmo-lab.bsky.social @icce-unidue.bsky.social @kulathu.bsky.social and others on how ATXN3 restores lysosome integrity after damage by targeting K48- and K63-branched ubiquitin chains. Full story: www.embopress.org/doi/full/10....

@unidue.bsky.social @crc1430.bsky.social @dfg.de

A fantastic example of what strong collaborations can achieve! Congrats 🎉 to our @crc1430.bsky.social members from @maltegersch.bsky.social, Grüner, Paschen, Knapp, Kaiser labs, and our core facilities ACE & @icce-unidue.bsky.social Especially proud of our PhD students for their excellent teamwork!

📊⚖️Our #Team "Financial & Legal Frameworks of Core Facilities" met in Eisenach for their writing workshop!

They focus on sustainable funding models & legal frameworks for operating technology platforms in Germany.

💬 Want to get involved?
👉 Meet the team: bit.ly/4mjlrue

Congrats to our @crc1430.bsky.social members from the Nalbant Lab, Paschen Lab, and @icce-unidue.bsky.social , along with collaborators, on their exciting preprint in @biorxivpreprint.bsky.social — highlighted by @prelights.bsky.social! 🎉 A great example of what strong teamwork can achieve. 🧑‍🔬👩‍🔬

Artificial intelligence-based chatbot created for bioimage analysis | UC3M Content shared from the official website of the Carlos III University of Madrid - www.uc3m.es

Have you met BioImage.IO Chatbot yet?
📰 Read articles in the press:
@uc3m.es: www.uc3m.es/ss/Satellite...
EurekAlert!: www.eurekalert.org/news-release...
AlphaGalileo: www.alphagalileo.org/es-es/Item-D...
🎥 Check out this interview with C.Fuster & @arratemunoz.bsky.social:
youtu.be/k-LFfXh-emE?...

🚨 Save the Date! 🚨
AI4Life & @globias.bsky.social are hosting a 4-part webinar series to showcase AI4Life services and lessons learned.

📅 When: Feb 13, Apr 10, Jun 12, Aug 14
🖥️ How: Online | 🎥 Recorded
🔗 Registration: bit.ly/registration...

Join us tomorrow, January 28, for an exciting @crc1430.bsky.social seminar at @unidue.bsky.social ! We’re happy to welcome Sascha Martens @maxperutzlabs.bsky.social @univie.ac.at, who will present on "Mechanisms of Selective Autophagy."

Reflecting on the @crc1430.bsky.social Female Get-Together ☕💡
Thank you to all the amazing women who joined for coffee and a great discussion on improving our meetings. 🚀 Your ideas are invaluable—looking forward to seeing even more of you next time! 🌈
#WomenInScience #Collaboration

Cartoon showing an overview of GPCR signalling. Following agonist binding, the GPCR undergoes a conformational change, enabling it to bind and activate a heterotrimeric G protein. G protein signalling is determined primarily by the type of Gα subunit, which falls into one of four subfamilies: Gαs, which is coupled to activation of adenylyl cyclase and production of cAMP; Gαi/o, which is coupled to inhibition of adenylyl cyclase and activation of phosphodiesterase to decrease cAMP; Gαq/11, which is coupled to activation of phospholipase C and subsequent mobilisation of intracellular Ca2+ through IP3 receptors; and Gα12/13, which is coupled to activation of Rho GTPases. Activated GPCRs are phosphorylated by GRKs, enabling recruitment of β-arrestins. β-arrestins can interact with the AP2 complex, which then interacts with clathrin and elicits the formation of a clathrin-coated pit, followed by endocytosis and receptor internalisation. Following internalisation, some GPCRs can continue signalling via G proteins from subcellular compartments.

In their #OpenAccess Review, Abigail Pearce, Theo Redfern-Nichols, David Prole, Graham Ladds and colleagues discuss the latest approaches for quantitatively studying G protein-coupled receptor signalling in cells.
journals.biologists.com/jcs/article/...

💡 Innovation from the Galstyan Lab at @unidue.bsky.social ! By generating photoactive membranes, they’re investigating the potential antibiotic role of reactive oxygen species. FLIM imaging at the ICCE revealed active sites for the first time! 🔬 Read more in Angew. Chem. 📚
#Nanotechnology #ICCE #UDE

👩‍🔬 Tomorrow’s @crc1430.bsky.social Female Scientist Get-Together will focus on enhancing our meeting format for even greater impact. Female scientists—whether you're a regular or it’s your first time—are warmly invited to join and share your ideas. Your voice matters!🌟 #WomenInScience #Collaboration