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Will Fuller

@fuller-lab.bsky.social

Professor at University of Glasgow. Interested in proteins, membranes, membrane proteins and post translational modifications, mostly in the context of cardiac myocytes. Also hillwalking and music.

1,201 Followers  |  1,556 Following  |  31 Posts  |  Joined: 16.11.2024  |  2.0525

Latest posts by fuller-lab.bsky.social on Bluesky

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Research Assistant/Associate at University of Glasgow Apply for the Research Assistant/Associate role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.

Well here’s an exciting opportunity! Who wants to spend 5 years working on S-acylation as part of a fantastic multidisciplinary team? #acylation #cellbiology #glasgow
www.jobs.ac.uk/job/DNB111/r...

16.05.2025 18:18 β€” πŸ‘ 9    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1

My esteemed colleagues will buy you a drink!

11.03.2025 15:36 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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This month is Heart Month! Professor Will Fuller explains what his research is about.

Will Fuller’s research group works on cellular and molecular mechanisms that control normal physiology in the heart, and how these things stop working properly to cause disease. (1/4)

28.02.2025 10:09 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Pass it on.
#StandWithUkraine

28.02.2025 20:44 β€” πŸ‘ 80935    πŸ” 34663    πŸ’¬ 1184    πŸ“Œ 1681

Thanks Dale! I’ll be working on the Addgene submission this weekend. We will share these reagents far and wide I hope.

08.02.2025 15:14 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

Massive thanks to the amazing people in my lab who contributed to this study, to collaborators who generously shared reagents, and to @thebhf.bsky.social for funding.

07.02.2025 17:21 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

And using a nanobody that binds the L-type calcium channel we depalmitoylate the pore forming subunit, shifting its voltage dependence and suppressing #arrhythmias in stem cell derived myocytes.

07.02.2025 17:21 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Using tricks developed by others to control the timing of nanobody binding, we built in a way to control when a protein is #palmitoylated or #depalmitoylated. We can induce target protein #depalmitoylation within an hour

07.02.2025 17:21 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Nanobody-thioesterase chimeras to specifically target protein palmitoylation - Nature Communications Reversible palmitoylation regulates the activity and localisation of numerous proteins. Here, Kuo et al develop nanobody-based reagents to specifically target palmitoylation of individual proteins, us...

Soooo excited to share this, just published. www.nature.com/articles/s41.... It started as a crazy β€˜Friday afternoon’ experiment and just… worked. And kept on working. We fused a #nanobody to a #thioesterase. This delivers the thioesterase to a target and specifically depalmitoylates this protein

07.02.2025 17:21 β€” πŸ‘ 22    πŸ” 5    πŸ’¬ 2    πŸ“Œ 4

Why have you changed dozens of instances of β€˜alpha1C’ in our manuscript to β€˜alpha1 C’? It isn’t a unit. It was right the first time.

03.02.2025 15:24 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Daybreak on the morning run 😍

17.01.2025 15:32 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Frozen hair, frozen eyebrows, frozen everything on Beinn Udlamain and SgΓ irneach MhΓ²r today! First hill of the year. Great to be out!

11.01.2025 18:13 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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A day making music in a beautiful location. Saint Seans and Strauss and an appreciative audience!

04.01.2025 23:33 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Two papers accepted in one week caps a remarkable year of success. There have been difficult and fallow years in my career. This has not been one of them and I will celebrate that! Cheers! πŸŽ‰β˜ƒοΈπŸŽ„

19.12.2024 18:17 β€” πŸ‘ 13    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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BBSRC injects Β£20 million into long-term discovery research BBSRC is backing four major research projects to help pioneer critical advances in healthy ageing, drug discovery and sustainable agriculture.

www.ukri.org/news/bbsrc-i...
Well, this is very exciting. A welcome boost to S-acylation research in the UK. Very much looking forward to working as part of a fantastic team

12.12.2024 10:03 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 4    πŸ“Œ 0
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A vote without a vote: the Saudi World Cup is an act of violence and disdain | Barney Ronay The shamelessness of Fifa’s process was fully on show in Zurich during a display of contempt for governance, democracy, love, hope and good sense

Give us your acclaim. Or don’t. It won’t really matter either way.
They used to pretend there was a vote. Now they don’t even bother with that #fifa #corrupt
www.theguardian.com/football/202...

12.12.2024 07:14 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Community sense check required… Reviewer asked us to show using proteomics that our new reagent doesn’t have off target effects. In a whole cell proteome, expression of one protein (our reagent) has changed. Reviewer: now you need to look at proliferation and viability assays. Feels unreasonable?

11.12.2024 08:32 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
University of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Underpinning Bioscience - A CHEMICAL BIOLOGY APPROACH TO IDENTIFY NOVEL SUBSTRATES...

Exciting opportunity for a really cool PhD project! www.gla.ac.uk/postgraduate...

09.12.2024 17:32 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
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Lab Christmas party! πŸŽ‰ πŸ₯³

05.12.2024 19:10 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Tentsmuir beach, December sunshine 😍

01.12.2024 13:54 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

We provide recordings of all lectures at the end of each block. Based on my colleagues experience this week 25 out of my class of 80+ will show up this morning. I massively value the opportunity to deliver teaching in person… but it is not particularly highly valued by the student body.

29.11.2024 08:25 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Empty lecture room

Empty lecture room

Empty lecture room

Empty lecture room

I love teaching in this space. Millions of times better than the lecture theatres I endured during undergrad days. Now I just have to hope the students turn up ready to hear about #lipidrafts

29.11.2024 08:17 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Stone arches with string lights lit up on the stone columns

Stone arches with string lights lit up on the stone columns

Our first post on Bluesky - the beautiful Cloisters and their twinkling string winter lighting @uofglasgow.bsky.social

Follow us to read about the amazing research stories and projects being undertaken across our campuses.

27.11.2024 18:59 β€” πŸ‘ 116    πŸ” 22    πŸ’¬ 2    πŸ“Œ 2

πŸ‘‹ + πŸ™

24.11.2024 20:41 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

One week on here and am already connected to a much bigger network than I managed in the other place. And no bots! #betterplace

24.11.2024 00:06 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

go.bsky.app/HqEcaCw

21.11.2024 19:19 β€” πŸ‘ 42    πŸ” 22    πŸ’¬ 14    πŸ“Œ 3

πŸ‘‹ + πŸ™

23.11.2024 08:12 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

πŸ‘‹πŸ™

19.11.2024 23:03 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

May be a bit premature, but here is the Starter Pack I am trying to populate for #IonChannel research. Ping me and I’ll add you obviously! (Or to be removed)
go.bsky.app/6taxHfx
@jgenphysiol.bsky.social @auditorynerves.bsky.social @plesslab.bsky.social @rainbowlabuol.bsky.social

19.11.2024 14:26 β€” πŸ‘ 29    πŸ” 15    πŸ’¬ 20    πŸ“Œ 1
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Ah, the annual magic of lab Christmas. This year they wrapped my office with me still inside it.

19.11.2024 19:11 β€” πŸ‘ 11    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

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