Patrick Zanon

Excited to share this preprint about the identification of TBK1 molecular glue degraders in a collaboration between NEOsphere Biotechnologies, @pmeier.bsky.social, and the Centre for Protein degradation @icr.ac.uk www.biorxiv.org/content/10.6...

06.02.2026 14:25 — 👍 4    🔁 2    💬 0    📌 0

This project started 5 years ago. It led us to add isotope-labeling support to #FragPipe/#IonQuant. Since then, the tools have grown so much and are now widely used in #Chemoproteomics.

Huge thanks to everyone, and special thanks to @stephanhacker2.bsky.social and @pzanon.bsky.social

30.10.2025 14:15 — 👍 15    🔁 5    💬 0    📌 0

I am thrilled to see the paper out now and grateful to all coauthors for their contributions to this work!
Among a number of changes, we included additional probes as well as experiments in live bacterial cells. So be sure to check it out even if you are already familiar with the preprint!

31.10.2025 16:38 — 👍 7    🔁 1    💬 0    📌 0

Here Are the Nearly 2,500 Medical Research Grants Canceled or Delayed by Trump (Gift Article) Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.

New powerful article up in the New York Times on cancelled and delayed grants

www.nytimes.com/interactive/...

04.06.2025 15:00 — 👍 302    🔁 208    💬 11    📌 14

We are looking for a PhD candidate in medicinal / organic chemistry with a passion for drug discovery to join our young and enthusiastic team @univie.ac.at. For details, visit: jobs.univie.ac.at/job/Universi.... Reposts are very much appreciated!

14.05.2025 17:01 — 👍 13    🔁 7    💬 0    📌 0