Nathan Grubaugh

The role of climate variability in shaping the 2023/24 outbreak of Dengue in Brazil (📉 in north regions; 📈 in southern populous regions).

Brazil recorded the largest outbreak on record which coincided with the warmest ever reported temperatures in the Americas.

www.medrxiv.org/content/10.1...

Implications of successive blood feeding on Wolbachia-mediated dengue virus inhibition in Aedes aegypti mosquitoes - Nature Communications Dengue virus transmission by Ae. aegypti mosquitoes poses a significant public health threat, necessitating innovative control strategies. Here, the authors demonstrate that, while successive blood feeding increases earlier dengue virus dissemination, the inhibitory effects of Wolbachia remain strong, highlighting Wolbachia’s potential to disrupt dengue transmission under natural feeding conditions.

Implications of successive blood feeding on #dengue virus inhibition by Wolbachia in Aedes aegypti mosquitoes

@entomososwin.bsky.social @mallerybreban.bsky.social @brackneylab.bsky.social @chantalvogels.bsky.social @yaleemd.bsky.social

A targeted amplicon sequencing panel for cost-effective high-throughput genotyping of Aedes aegypti The mosquito Aedes aegypti is the primary vector for several medically significant arboviruses, including dengue, Zika, chikungunya, and yellow fever. Studying the genetic diversity of Ae. aegypti is ...

🚨 New preprint alert! We have developed a targeted amplicon sequencing panel for Aedes aegypti. We believe it is a powerful and cost-effective tool for studying #mosquito #population #genetics. Curious how it matches up to WGS? Check out our preprint to find out! www.biorxiv.org/content/10.1...

Director of Eisenhower Library in Kansas ousted after refusing to give Trump administration a sword The director of the presidential library and museum in Abilene, Kansas, said he was suddenly told to resign or be fired. He refused to give the Trump administration a historic sword from the museum’s collection.

BREAKING: The director of the presidential library and museum in Abilene, Kansas, said he was suddenly told to resign or be fired. He refused to give the Trump administration a historic sword from the museum’s collection.

Quantifying the impact of a broadly protective sarbecovirus vaccine in a future SARS-X pandemic - Nature Communications Broad-spectrum vaccines have been proposed as a tool for rapid response to emerging infectious disease threats and are in pre-clinical development. Here, the authors use mathematical modelling to assess the potential impacts of broadly protective sarbecovirus vaccines for a hypothetical “SARS-X” outbreak.

Huge congrats to @charleswhittaker.bsky.social and team on one of the most important modeling papers of the year - the investment case for a universal vaccine against SARS-like viruses (and an important blueprint for other similar studies!) www.nature.com/articles/s41...

Modeling the Health Impact of Discontinuing COVID-19 Vaccination During Pregnancy in the US This decision analytical model study estimates the number of avertable COVID-19 hospitalizations in US infants younger than 6 months and pregnant persons with vaccinations during pregnancy.

What is the impact of the HHS decision to no longer recommend COVID-19 vaccination during pregnancy? In our new research letter in @jamapediatrics.com, we provide estimates on the number of infant hospitalizations under different vaccine scenarios here. @mathewkiang.com, @peterhotezmdphd.bsky.social

This is probably someone's dream job, and could have some remote flexibility for the right person. We have a lot to do, and we're looking for someone with a really strong track record who can come here and build something big with us and @cchyale.bsky.social (and many great external collaborators).

Official communication from FDA to physicians on acetaminophen use in pregnancy acknowledges there is no causal link between its use in pregnancy and autism. Also states clearly that this is the safest over the counter treatment for fever and pain in pregnancy. It is very different from what was communicated at the press conference.

This is the official communication from the FDA to physicians on acetaminophen use in pregnancy.
- They acknowledge the lack of a causal link with autism
- Essentially tell physicians to keep doing what we've been doing anyway
It's very different from the press conference.
Pass it on.

Faculty Professor Associate - Full-Time | Vaughn Cooper We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine. 1) Fundamental researc...

🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...

Heterogeneity in inhibition of genetically diverse dengue virus strains by Wolbachia The release of Aedes aegypti mosquitoes transinfected with the virus-inhibiting Wolbachia bacterium has the potential to reduce the burden caused by dengue virus (DENV). However, the robustness of thi...

📢New preprint on the impact of dengue virus genetic diversity on inhibition by Wolbachia 🦟🦠🧬

Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨

Key findings in thread below 👇

www.biorxiv.org/content/10.1...

This commentary offers a clear, powerful statement of why freedom of speech is at the heart of democracy and must be defended, whether the speaker is Charlie Kirk or Jimmy Kimmel, MAGA supporters or MAGA opponents.

"Health losses attributed to anthropogenic climate change," a brief communication in the journal Nature Climate Change. There's a map showing regions of the world, and pie charts of relevant studies as they apply to different health impacts like "heat-related deaths" and "maternal and child health"

🚨 NEW: Climate change is already causing 30,000 deaths per year - a global annual economic loss of $100-350B USD - but the true damage is probably 10x higher. Out TODAY in Nature Climate Change: the first systematic look at the science of "health impact attribution" 🔓 www.nature.com/articles/s41...

Though it’s traumatic for me to bring this up, I was targeted by a group allied with Turning Point USA in 2018, with the help of Tucker Carlson on Fox. My home address circulated online and I got death threats. 1/

Figure 3 of our paper, which shows viral coinfection networks at the virus level

New preprint! 🥳🎉 We looked at viral coinfection patterns at the largest scale ever in wildlife. We found a strong association among CoVs, PMVs, and influenza A, and higher coinfection rates in wildlife trade; plus, evidence that bats accumulate persistent infections. www.biorxiv.org/content/10.1...

🎉✨👏 Welcome to a new academic year in the Department of Epidemiology of Microbial Diseases at the Yale School of Public Health! We’re excited to continue learning, collaborating, and advancing public health together.

Cross-reactive human antibody responses to H5N1 influenza virus neuraminidase are shaped by immune history H5N1 highly pathogenic avian influenza viruses have spread globally and pose a risk for a human pandemic. Prior studies suggest that early life exposures to group 1 influenza viruses (H1N1 and H2N2) p...

A new study led by @cambupenn.bsky.social Jordan Ort in my lab was posted on medRxiv. We found that humans infected with H1N1 viruses in childhood have high levels of Abs that cross-react to the NA of H5N1 viruses...decades after their childhood H1N1 infections. 1/

www.medrxiv.org/content/10.1...

I'll keep saying it: RFK Jr. is a deadly threat to our public health and safety.
 
He is razing CDC, NIH, and other health agencies to the ground—putting politics and deranged conspiracy theories over science.
 
We need bipartisan oversight immediately, and he must be FIRED.

👏 Proud of my Yale colleagues Gregg Gonsalves and Jeff Wickersham for helping organize this important event. Grateful for their strong and consistent leadership in advancing HIV/AIDS research and public health!

#EndHIV #PublicHealth #Research @gregggonsalves.bsky.social

Opinion | We Ran the C.D.C.: Kennedy Is Endangering Every American’s Health

#CDC directors going back to 1977 tell the truth about #RFKJr: he is endangering the health of every American. www.nytimes.com/2025/09/01/o...

I miss the old brand #CDC

Trump knew RFK Jr. would be a disastrous pick to lead health care in America, and he nominated him anyway.

Trump made this mistake, and now he must fire RFK Jr. immediately.

Pharos Building a global atlas of wildlife disease data

Just spent my lunch with @nathangrubaugh.bsky.social getting some of his lab's old mouse coronavirus data up on Pharos. Super easy! Beautiful data! Do you have data you'd be willing to share? Reach out! pharos.viralemergence.org/projects/?pr...

All together now:
DUMP RFK Jr.

A screenshot of the Pathoplexus homepage, now showing Measles among the other pathogens supported.

🎉 New in August: Measles virus joins Pathoplexus!

Following strong community support, we added MeV data submission (with Open & Restricted-Use options, as always) and powerful search & data access for MeV
pathoplexus.org/measles/search

5/10

2 x Postdocs (Berkeley, CA, USA)
Infectious-disease modelling & phylodynamics for pandemic preparedness
with ‪@charleswhittaker.bsky.social‬
at @petal-team.bsky.social‬ @ucberkeleyofficial.bsky.social‬ ‪@berkeleypublichlth.bsky.social‬
More details: http://iddjobs.org/jobs/2351

E&E News: People are dying from climate change. But how many? A team of researchers hopes to provide the long-elusive answer, thanks to the growing field of attribution science.

I'm delighted today to announce we're launching the Global Burden of Climate Change Study, an international team effort to standardize estimates of present day death, disability, and illness due to climate change. @chelseaeharvey.bsky.social with the scoop: subscriber.politicopro.com/article/eene...

US Supreme Court lets Trump cut diversity-related NIH grants The U.S. Supreme Court let President Donald Trump's administration on Thursday proceed with sweeping cuts to National Institutes of Health grants for research related to racial minorities or LGBT people, part of his crackdown on diversity, equity and inclusion initiatives and transgender identity.

There is no solace for NIH funded researchers in this Supreme Court decision. Grants that were ripped away on dubious grounds, restored by a reasonable judge are now again terminated by an out-of-control Supreme Court. Labs will shutter, people will lose jobs. www.reuters.com/world/us/us-...

Reskeet please. As the fall semester is upon us I'm reposting this. Looking for 1-2 students (US based only). The lab is open to interests in ecology, evolution, systematics, and taxonomy of mosquitoes. Work could take place in Puerto Rico, around the Gulf Coast, or could even involved museum work.

Our lab has an opening for a research technician to contribute to our efforts to understand RSV evolution & its impact on antibody countermeasures (see journals.asm.org/doi/full/10....). The tech will also help w lab management.

If interested, apply here: careers-fhcrc.icims.com/jobs/29940/job