Ancient amino acid sets enable stable protein folds
Early proteins likely arose from a chemically limited set of amino acids available through prebiotic chemistry, raising a central question in molecular evolution: could such primitive compositions yie...
Can proteins fold and function with half of the amino acid alphabet?
Using only 10 residues, we designed stable, mutation-resilient structuresβno aromatics or basics involved.
A minimalist foundation for ancient biology and synthetic design. tinyurl.com/37t8br4v
#ProteinDesign #OriginsOfLife
03.11.2025 16:48 β
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22nd Structural Biology Club online on 26th November 2025, 1pm CE: Structures in solution: BioSAXS at BM29 ESRF
by Petra Pernot & Cryo-EM data processing in CCP-EM Doppio
by Colin M. Palmer cssb.structbio.org/22nd-structu...
23.10.2025 15:16 β
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Homology modeling
10.10.2025 16:17 β
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Gruezi!
02.10.2025 07:48 β
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Protein Production Hands-On Workshop Dates: December 2 β 4, 2025 Venue: BIOCEV, Vestec Registration Deadline: October 31, 2025 Cost: Free of charge (accommodation not included) Registration Link: forms.biocev.org/index.php/14... Workshop Page: www.ibt.cas.cz/en/core-faci...
02.10.2025 07:44 β
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Thanks!
24.09.2025 15:02 β
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YouTube video by Vojtech Spiwok
Protein design by parallel tempering in the sequence space
youtu.be/4n4awaRnEOY
24.09.2025 14:59 β
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YouTube video by Vojtech Spiwok
Protein design by parallel tempering in the sequence space
youtu.be/4n4awaRnEOY
24.09.2025 14:57 β
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Our first protein design paper out in Protein Science
onlinelibrary.wiley.com/doi/10.1002/...
24.09.2025 14:53 β
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Pranam Chatterjee @pranam.bsky.social and his first AI-generated baby #CecamLLMLugano
24.09.2025 09:19 β
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#CecamLLMLugano
24.09.2025 08:50 β
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Traveling to "Generative AI and large language models for protein modeling across sequence-structure-function scales : From predicting protein dynamics to programmable biology and drug design" in Lugano #CecamAILugano @cecamevents.bsky.social
24.09.2025 08:26 β
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Max Bonomi @bonomimax.bsky.social on IDP modeling by AI @cecamevents.bsky.social #CecamLLMLugano
24.09.2025 08:23 β
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Prof. Michele Vendruscolo
Dr. Zsuzsanna DosztΓ‘nyi
ML4NGP Connect series, organized as part of the ongoing activities of the ELIXIR 3D-BioInfo Community and in collaboration with ISCB and 3DSIG.
π’ Date & Time: 30 September 2025 | 17:00-18:00 CEST
Online elixir-europe.org/events/unstr...
09.09.2025 10:18 β
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Happy birthday ΔSBMB #CSBMB2025
07.09.2025 17:32 β
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Hana CahovΓ‘ ( @iocbprague.bsky.social ) awarded a medal by CSBMB #CSBMB2025
07.09.2025 15:21 β
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#csbmb2025
07.09.2025 15:19 β
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Kickoff of XXVIII-th congress of the Czech Society for Biochemistry and Molecular Biology ( @febspress.bsky.social member )
07.09.2025 14:30 β
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π§
22.08.2025 15:40 β
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New Horizons in Protein Dynamics β Department of Biology - University of Copenhagen
Instruct Director Harald Schwalbe will be in Denmark for the SBiNLabβs 25th anniversary!
www1.bio.ku.dk/english/rese... @schwalbe-lab.bsky.social
Researchers in Denmark can receive access to Instruct technologies and instrumentation here - instruct-eric.org/submit-propo...
22.08.2025 15:22 β
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Many thanks to @pluskal-lab.org @iocbprague.bsky.social @elixircz.bsky.social for two days of excellent talks at #PragueBioML !
22.08.2025 15:32 β
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And now something completely different - nanopores! by @scimartin.bsky.social @ethz.ch #PragueBioML @elixircz.bsky.social
22.08.2025 15:23 β
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Erik Andris @iocbprague.bsky.social on graph NNs #PragueBioML @elixircz.bsky.social
22.08.2025 15:05 β
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"Second talk" by Anton Bushuiev ( @iocbprague.bsky.social @pluskal-lab.org @josef-sivic.bsky.social ) on protein language models #PragueBioML @elixircz.bsky.social
22.08.2025 14:49 β
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Intrinsically disordered proteins by @tothpetroczylab.bsky.social #PragueBioML @elixircz.bsky.social
22.08.2025 14:13 β
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In 2024, IT4Innovations supported thousands of users and hundreds of research projects.
Behind every achievement stand people β our colleagues, partners, and supporters β thank you for making it possible.
π¬π§ www.it4i.cz/cs/file/e5d7...
#eINFRAcz
22.08.2025 13:24 β
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Petr Kouba on protein flexibility #PragueBioML @elixircz.bsky.social
22.08.2025 13:18 β
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Joan Planas-Iglesias on protein aggregation #PragueBioML @elixircz.bsky.social
22.08.2025 13:01 β
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Stanislav Mazurenko on evolution and protein design #PragueBioML @elixircz.bsky.social
22.08.2025 12:40 β
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