The International Scientific Assoc for Probiotics & Prebiotics

International Scientific Association for Probiotics and Prebiotics (ISAPP) ISAPP is the only organization dedicated specifically to advancing the science of probiotics, prebiotics, synbiotics, postbiotics and fermented foods.

👀Have you seen it yet? The ISAPP website has a fresh new look!

Check it out and browse by topic for the latest scientific content on biotics:

isappscience.org

Clinical evidence and not microbiota outcomes drive value of probiotics - International Scientific Association for Probiotics and Prebiotics (ISAPP) By ISAPP Board of Directors, plus Prof. Francisco Guarner and Dr. Bruno Pot September 10, 2018 Two recent papers have generated much adverse publicity for the probiotic field. Headlines driven by sens...

This article from our blog archives is a great reminder that the value of probiotics does NOT come from any effects it may have on the microbiota, but from the measurable health effects it has on the host. Read here:

isappscience.org/clinical-evi...

ISAPP was pleased to hold a joint symposium with the European Society of Neurogastroenterology and Motility addressing the question: "Is gut health a meaningful concept in neurogastroenterology?"

Stay tuned for ISAPP's gut health definition paper, to be published soon!

Probiotic yeast Saccharomyces boulardii is gaining attention for its unique traits and engineering potential. Could it power the next generation of therapeutic probiotics? Learn more in our latest ISAPP-SFA blog🔬 @isappscience.bsky.social

📖 www.isapp-sfa.com/new-blog/202...

Is Kombucha Good for You?

The New York Times covered the science of kombucha this week! The article features words from Prof. Dan Merenstein MD, a member of our board of directors:

www.nytimes.com/2025/08/26/w...

Highlighted Talks from the 2025 ISAPP Annual Meeting - International Scientific Association for Probiotics and Prebiotics (ISAPP) In this special episode, ISAPP’s Executive Director Marla Cunningham highlights ISAPP’s annual meeting, held in Banff, Canada in July 2025. Four speakers join the podcast to describe their talks from ...

Get an overview of some of the scientific highlights from our annual meeting, held last month! This podcast episode features 4 speakers from our meeting, covering the varied topics of biosensor microbes, metabolic health, psychobiotics, & vaginal health.

isappscience.org/episode-66-h...

Microbiome endpoints in clinical trials for biotics - where do we stand and what have we learnt? - International Scientific Association for Probiotics and Prebiotics (ISAPP) This blog summarizes the latest thinking around microbiome endpoints in clinical trials for probiotics, prebiotics, and other biotics.

Planning a clinical trial for probiotics (or other biotics) and wondering about the value of including microbiome endpoints? ISAPP recently delved into this topic in a series of podcasts -- and you can find a summary of learnings here on our blog.

isappscience.org/microbiome-e...

What a great event!! So happy to have you there.

🔥Hot topic alert! Our latest podcast episode with Dr. Thomas Greiner of Bäckhed lab covers GLP-1 in the gut and its contributions to metabolic health.
Listen now:
isappscience.org/episode-65-u...

ISAPP gathers in Banff, Canada this week! Our gala dinner was a great chance to honor this year's outgoing board members, Profs. Colin Hill & Eamonn Quigley -- and have some fun with line dancing, s'mores, and more 🍫

In this podcast episode, it was a treat to hear from Dr. Amir Zarrinpar about how microorganisms contribute to circadian rhythms and metabolic health! Tune in to this fascinating conversation for insights on time-restricted eating & more.

isappscience.org/episode-64-i...

In our latest podcast episode, Prof. Dirk Haller explains his research spanning from nutrition to immunology to gut microbiota, all with the goal of understanding contributions to chronic disease. Listen here:

isappscience.org/episode-63-i...

Kefir that improves cardiometabolic health: is it far-fetched or scientifically feasible? On our latest podcast, hear from Prof. Ben Willing, who's studying the health benefits of traditional fermented foods and what microorganisms (or other factors) drive them.

isappscience.org/episode-62-e...

The International Probiotics Association has officially adopted ISAPP's scientific consensus definition of prebiotics -- a stance that will encourage scientific clarity, regulatory alignment, and commercial harmonization across the field. Read more here:

internationalprobiotics.org/home/the-ipa...

Today we launch our series of podcasts on metabolic health through the gut! In this episode, Dr. Karen Corbin PhD RD describes the detailed way in which she studies host energy balance, and how it can reveal the contributions of gut microbes.

isappscience.org/episode-61-d...

Check out this joint ESNM & ISAPP session on the concept of gut health, coming up at the NeuroGASTRO 2025 conference. Early bird registration ends June 9th!

www.neurogastro2025.org/registration...

We're so pleased to hear from Prof. Emad El-Omar MD FRCP, editor of Gut journal, on this week's podcast!

He describes recent progress in defining a healthy gut microbiome, as well as the latest causal links between the gut microbiome & specific GI diseases.

isappscience.org/episode-60-p...

Have you heard about the HACK index as an approach for measuring a health-associated gut microbiome across multiple geographies? Dig into the details in our latest podcast with computational microbiologist Dr. Tarini Shankar Ghosh.

isappscience.org/episode-59-t...

On our podcast, the ISAPP hosts talk regulatory science & how it can support microbiome-based biomarkers! Hear from our guest, Dr. Celine Druart PhD of PRI:
isappscience.org/episode-58-r...

Check out our latest podcast episode! Continuing with our "healthy microbiome" series, Raphaela Joos of University College Cork describes how the Human Microbiome Action Consortium created an expert-led consensus around the concept of a healthy human microbiome.

isappscience.org/episode-57-i...

Fermented foods in a global age: East meets West Fermented foods and alcoholic beverages have long been an important part of the human diet in nearly every culture on every continent. These foods are often well-preserved and serve as stable and sig...

See the ISAPP-led paper first-authored by Jyoti here: ift.onlinelibrary.wiley.com/doi/10.1111/...

The ISAPP community is saddened by the loss of a valued colleague: Prof. Jyoti Tamang of Sikkim University in India.

Exploring resources to inform probiotic recommendations: New UK Probiotic Guide Released - International Scientific Association for Probiotics and Prebiotics (ISAPP) A new resource is available to clinicians who seek to make evidenced-based probiotic recommendations to patients for specific purposes.

Not all probiotics do the same thing! They must be backed by #Clinical #Evidence and the evidence needs to be sufficient. Read the whole post: isappscience.org/exploring-re... #GutHealth #DigestiveHealth
@isappscience.bsky.social

Today we kick off our new podcast series on what makes a "healthy microbiome"! Our first episode features Dr. Gianluca Ianiro of Italy talking about a recent consensus paper on microbiome testing. Listen here:
isappscience.org/episode-56-a...

ISAPP is pleased to share a new resource by AEProbio (Alliance for Education on Probiotics) for clinicians in the UK who want to know the evidence behind specific probiotic products! Read about it here:
isappscience.org/exploring-re...

Have you seen the hot-off-the-press "NiMe Diet" paper? Dr. Anissa Armet PhD RD explains the study in this edition of the podcast. (Plus, see the show notes for the NiMe Diet cookbook with the study's high-fiber recipes!)

isappscience.org/episode-55-h...

A research funding opportunity from the US NCCIH for fundamental science on complementary & integrative health approaches, including novel microbial strains or mechanisms for microbial-based therapeutics addressing specific health outcomes:
grants.nih.gov/grants/guide...

Precision fermentation is a cutting-edge technology in food science -- find out exactly how it works in this podcast with Prof. William Chen of Singapore.

isappscience.org/episode-52-a...

Our latest podcast episode features Prof. Yves Desjardins (plant scientist 🌿) giving an overview of what polyphenols are & how they create niches for certain bacteria in the gut.
Listen now:
isappscience.org/episode-54-i...

How to respond to the question “Should I take a probiotic?” - International Scientific Association for Probiotics and Prebiotics (ISAPP) Two experts explain the science of probiotics and how to answer the question of whether you should take a probiotic.

"Should I take a probiotic?" is a common question that clinicians receive. Here's an answer that's based on the latest science.
isappscience.org/how-to-respo...