Jan Mašek

Jan Mašek

@maseklab.bsky.social

PI at CUNI Prague🇨🇿, Karolinska Institutet🇸🇪, Czexpat🌍, Junior Faculty chair. Notch & Wnt in development and disease 🔬🧫🐁. *All views my own; 🇪🇺🇺🇦 https://maseklab.org

247 Followers 200 Following 48 Posts Joined Nov 2024
1 month ago
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Today at PI_Forum Brno we will discuss this graph.
From 62% women at PhD level to 17% at professor level.
Let’s talk about why this happens—and how to change it. 📍 CEITEC MU | 🕠 17:30 czexpats.org/en/udalost/p... @czexpats.bsky.social

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1 month ago

Thanks for the kind words Alfonso! Very happy to discuss and learn from you if you would be interested.

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1 month ago
Preview
Decoding 'Wntch': the intertwined Wnt and Notch pathways in development and disease - PubMed Multicellularity emerges from the ability of cells to undergo functional differentiation. One of the key mechanisms that enables this coordination is cellular signalling-a series of molecular interactions within or between cells that induce changes in cell behaviour or gene expression. As the body p …

Huge thanks to @fabioturetti.bsky.social, Marek Dokoupil, and the one and only Giovanna Collu, who worked on this review, and to @amartinezarias.bsky.social who pioneered this field pubmed.ncbi.nlm.nih.gov/22326376/ 🫶. #Wnt #Notch pubmed.ncbi.nlm.nih.gov/41558807/ #openbiology

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1 month ago
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Together with @harnoslab.bsky.social, we compiled what is known about direct interactions of Wnt and Notch components, and advanced the testable framework of how the crosstalk could allow for a more polarized cellular response to one pathway or the other.

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1 month ago

Paper alert! 🤓 Cells talk to one another all the time using cascades of protein interactions. Now, we know for quite some time that proteins from different cascades can interact with each other. It's called crosstalk. But doesn't it defy the logic of clear communication channels between cells? 🧐

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3 months ago
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Author copies of our new book on statistics (mainly) for life scientists arrived recently. After three years of work, this is exciting, especially as we really hope it can help make a positive difference.

What's so special about it?

🧵

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3 months ago

Great article about starting a lab at @sciencecharles.bsky.social and the positive effect of supportive peer community from my colleague and co-chair of JF Vito @geohazards.group. For more context check also my article in @vedavyzkumcz.bsky.social - vedavyzkum.cz/nazory/nazor....

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3 months ago

Big congratulations Jesse!!

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4 months ago

Big thanks to all speakers (keynotes🤩), audience for discussions. Amazing job by organizers from PhD program Mehak Shaikh, Jonáš Vlasák, @annafrontino.bsky.social , @fabioturetti.bsky.social and Štěpánka Martiskova, and generous support from @nf-iocbtech.bsky.social and @sciencecharles.bsky.social !

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4 months ago
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We are closing the scientific program with talk from Ruslan Nyshchuck, who works on the Usher syndrome in minipig model.

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4 months ago
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Moving to brown adipose tissue to learn about function of VW8A function in lipid metabolism from Habib Hayat.

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4 months ago
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Next, we learn about the tumor-immune system interface in melanoma from Salim Abuhajiar.

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4 months ago
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Back to mitochondria biology with Michal Knězů and his cool talk on cytochrome C oxidase isoforms.

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4 months ago
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Starting the last session of today with Anastasiia Kolesnikova and her insight into Huntington disease from minipig model.

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4 months ago
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Now, closing the session 4 with Karolína Kowalska showing her cool work on Mical protein in axonal guidance.

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4 months ago

Next, Adela Maraclikova takes us into development of sensitive sensors of bacterial proteases in priodontitis and Alzheimer's disease. (Apology here I forgot to take a picture)

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4 months ago
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We like to keep the audience on tip of their toes, and we jump into the story of finding the ideal NK cell donors for immunotherapies, presented by Eva Mašínová.

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4 months ago
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We take a sharp turn into the dark universe of possible protein structures that don't usually exist in biological system thanks to Tereza Neuwirthova.

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4 months ago
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Next speaker is our keynote neurobiologist from Norway, Giulia Quattrocolo @gquattrocolo.bsky.social, with an awesome talk on axonal cone biology! 🤩

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4 months ago
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First session of the day is closed by Yaroslav Nemesh who focuses on Dry AMD-related transcriptomic changes in the RPE cell model.

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4 months ago
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From mitochondria to homologous recombination! Matouš Palek reports his findings of how RAD18 directs DNA double-strand break repair by homologous recombination to post-replicative chromatin.

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4 months ago
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We continued with Maria Jose Saucedo-Rodriguez, studying the impact of SDHA Mutations on SDH Assembly and Function

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4 months ago
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Day of the DevCellBiol conference is here! Starting with Anna Macečková Brymová, working on human iPSC-derived RPE cell transplantation as a potential advanced medicinal therapy

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4 months ago
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And the final talk of today, Karel Fusek on recombination hot spots. After his talk we move to poster session of the 1st year PhD students.

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4 months ago
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Moving on to genome stability in oocytes and somatic cells, presented by Nataliia Dudko!

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4 months ago
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Now back to c. elegans with Allan Akandwanaho and his talk about chirality in actomyosin cortex.

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4 months ago
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Let's stick to nucleic acids with Jiří František Potužník's talk on mRNA capping.

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4 months ago
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Short break and we are back! Shreyas I Mazumder is taking us to the realm of telomeres.

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4 months ago
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Last speaker of the first session is Fatima J. Berro, taking us to the mRNA regulation in the oocyte.

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4 months ago
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Switching gears to c elegans early development with Subhadip Chakraborty!

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