Danielson Baia Amaral

So proud of this incredible team and all we accomplished this year!

We’re looking for 1-2 postdocs to explore evo-devo, organ regeneration, extreme physiology, non-traditional animals, and

SUPERMAN 🦸‍♂️!

Please spread out news.
@isrbio.bsky.social @ahascience.bsky.social @socdevbio.bsky.social

Exciting genome news! For those interested, there is a prerelease of the Ensembl gene models for the new reference genomes GRCz12tu (GCA_049306965.1) and GRCz12ab (GCA_05204075.1) at ftp.ebi.ac.uk/pub/database...
You can download gff and gtf files there as well as softmasked genomes.

Celebratory drink with @compbiologist.bsky.social to salute the new year AND to cheer for @yhbioinfo.bsky.social’s new article on cross-species comparison methods out in Nature Methods: www.nature.com/articles/s41...

Rapid continuous evolution of gene libraries towards arbitrary functions The emergence and evolution of new gene functions is central to biology, yet experimental tools that allow us to prospectively probe and understand this process are lacking. While systems for continuo...

We’re excited to share new work on the continuous in vivo evolution of gene libraries towards arbitrary functions. Led by superstar Olek Pisera, our experiments show that gene evolution is highly versatile...
www.biorxiv.org/content/10.1...

Directed evolution of aminoacyl-tRNA synthetases through in vivo hypermutation - Nature Communications Genetic code expansion (GCE) enables the incorporation of new amino acids into proteins. Here, authors demonstrate the rapid OrthoRep-driven evolution of aminoacyl-tRNA synthetases for GCE, increasing...

Happy to share the peer-reviewed and updated version of our work on OrthoRep-driven evolution of aaRSs for genetic code expansion with unnatural amino acids. Congrats to Yuichi Furuhata, a true master bioengineer, on leading this excellent work! www.nature.com/articles/s41...

CUT&ID for simultaneous profiling of protein-DNA and protein-protein interactions https://www.biorxiv.org/content/10.64898/2025.12.11.693662v1

#NIH modified how next peer review panel will #review #grants

grants.nih.gov/news-events/...

Thank you! 😊

💙💙💙😭😭😭

Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.

(Please repost to reach a broad audience.)

Thank you!!! 💙

Thank you!!!

Attention Junior RNA Scientists - The deadline to apply for RNA Junior Scientist Representative positions with the RNA Society @rnasociety.bsky.social is midnight tomorrow! We are so excited to review your applications and to recruit the next cohort of Jr RNA Scientists Representatives 🤩

Please help distribute this announcement for the Ph.D. in Biology Program @stowersinstitute.bsky.social

Adrenergic signaling coordinates distant and local responses to amputation in axolotl The nervous system regulates a systemic response following amputation that primes distant appendages for faster regeneration upon a second injury, a scenario relevant to salamanders in the wild who ex...

www.cell.com/cell/fulltex...

Thank you!! 👯👯👯

Cracking the code of the non-coding genome via allele-specific genomics?
Can we link non-coding elements—like lncRNAs and enhancers—to their protein-coding target genes, and in doing so, connect overlapping non-coding disease variants to their protein-coding counterparts?

The origin and molecular evolution of the mammalian liver cell architecture https://www.biorxiv.org/content/10.1101/2025.10.14.682049v1

Pathway to Independence: a forecast for the future of developmental biology ABSTRACT. In 2022, Development launched its Pathway to Independence (PI) programme, aimed at supporting postdocs as they transition to their first independent position. In 2025, we welcome our third c...

It's online! In this series of perspectives @dev-journal.bsky.social, yours truly talks about the exciting open questions and many things to do in the field of dev bio and neuroscience #DevBio🧪 #PIsOfTomorrow journals.biologists.com/dev/article/...

RMBase v3.0: decode the landscape, mechanisms & functions of RNA modifications
The Encyclopedia of RNA Epitranscriptome

More than m6A
"73 RNA modifications of 62 species"

bioinformaticsscience.cn/rmbase/

@narjournal.bsky.social 2024
academic.oup.com/nar/article/...

The Braasch Lab @fishevodevogeno.bsky.social will soon post a position to replace manager of our *Ancient Fish Facility* at Michigan State. Looking for aquaculturist excited for unusual 🐟 species (gar, bowfin, paddlefish, polypterus) + zebrafish. Pls send candidates our way (DM or braasch@msu.edu)!

ISRB Pre-Conference Trainee Meeting - Morgridge Institute for Research This pre-conference workshop is designed specifically for trainee-level members, including undergraduates, graduate students, and postdocs. The event will provide a platform for trainees to share thei...

Sign up for the ISRB Pre-Conference Trainee Meeting is closing tomorrow, 1st July. Don't miss out trainees! morgridge.org/event/isrb-p...

An axolotl in a clear tank

A new study from the MBL reveals that activating a group of neurons in the axolotl brain is essential for tail regeneration.

The findings point to the possibility that a comparable group of neurons impacts regenerative responses in mammals.

Read more: bit.ly/4kxcfRp

📷: Dee Sullivan

Register below! ⬇️

Check out our latest work on the evolution of animal genome regulation out today in @nature.com. Nicely summarized below by @ianakim.bsky.social.
www.nature.com/articles/s41...

This is a major output from our ERC-StG project Evocellmap @erc.europa.eu at @crg.eu

🚨ISRB Webinar Alert - Zone 3: The Americas 🚨 Join us on May 16th at 12pm US East Coast Time. Featuring Dr. Sarah McMenamin from @bostoncollege.bsky.social and Dr. Erica Crespi from @wsupress.bsky.social. Find all details at isrbio.org/event-6181293

🚨New paper alert!🚨
Our latest work uncovers how cells detect and destroy defective ribosomes before they cause harm. A key quality control pathway with implications for development and disease. #ribosome #qualitycontrol
Check it out in Molecular Cell:
authors.elsevier.com/a/1l2MA3vVUP...

Neural microexons modulate arousal states via cAMP signalling in zebrafish Arousal states, often dysregulated in neurodevelopmental disorders, shape how organisms perceive and respond to their environment. Here, we show that srrm3, a master regulator of neural microexons, is...

🐠 New pre-print from the lab! 🐠

Neural microexons fine-tune protein function - but how do they impact arousal states and underlying neuronal signaling pathways?

www.biorxiv.org/content/10.1...

Check out our latest pre-print by @tahneema.bsky.social et al, @upf.edu @crg.eu. 🧵👇 1/9

Today’s most transformative medicines exist because of fundamental discoveries that were made without regard to practical outcome.

Their relevance to therapeutics only appeared decades later.

This article provides some compelling examples.
🔽

From conservation to adaptation: understanding the synaptonemal complex’s evolutionary dynamics The synaptonemal complex (SC) is structurally conserved across eukaryotes and is essential for a proper progression of meiosis. Despite this conservat…

In this review, I write about why it is important to study synaptonemal complex protein evolution and highlight this with a few key examples of conserved features and unique adaptations.