FEBS Letters

🌍 Before RNA, could life have started with amyloids? 🧬 Self-replicating β-sheet peptides suggest a co-evolving amyloid–RNA–lipid–protein world – read the newest Perspective: febs.onlinelibrary.wiley.com/doi/10.1002/... #OriginOfLife #AmyloidWorld #RNAWorld

A new study by Tanmay Dutta et al. reveals a previously unknown function of YbeY in #smallRNA regulation in #Mycobacterium tuberculosis.
Online here ➡️ tinyurl.com/2enrhey8

🎉🎖️We congratulate 🌟Chia-Teng Chang (Washington University, St. Louis, MO, USA), winner of a FEBS Letters #PosterPrize at the 19th International #Zebrafish Conference, held in Madison, WI, USA! 👏👏👏

🎉We wish you all the best, Chia-Teng! 🎉

@izfs.bsky.social #IZFC2025

🎉🎖️Congratulations to 🌟Priyom Adhyapok (Duke University), on winning a FEBS Letters #PosterPrize at the 19th International #Zebrafish Conference, recently held in Madison, WI, USA! 👏👏👏🎉

🎖️We wish you all the best, Priyom! 🎉

@priyomadhyapok.bsky.social @izfs.bsky.social‬ #IZFC2025

🎉 🌟Tamir Dingjan (Weizmann Institute of Science) won a FEBS Letters #PosterPrize at the FEBS Special Meeting on #Sphingolipid Biology in Varna, Bulgaria!

👏👏👏Congratulations, Tamir! 🎖️🎉

@slbiology.bsky.social‬

🧬With 90+ genes behind retinitis pigmentosa, gene therapy isn't always an option. Could targeting cGMP/cAMP pathways offer a broad treatment strategy? 👁️ Read more: febs.onlinelibrary.wiley.com/doi/10.1002/...
#Retina #Ophthalmology #Neurodegeneration

Recombinant proteins are commonly used to investigate #proteinaggregation--but can purification tags themselves affect aggregation? 🤔 A new study published in @febsletters.bsky.social suggests this may be the case ➡️ tinyurl.com/yhecdb3j

Thank you for all your support with this excellent Special Issue!

🔬 Extracellular vesicles shape immune crosstalk in B-cell malignancies—but remain elusive. Explore the latest insights from new single-EV & single-cell tools: febs.onlinelibrary.wiley.com/doi/10.1002/...
#EVs #CancerResearch #BCellLymphoma @danielbachurski.bsky.social

Our special issue on dendritic cell biology in health and disease is online now!
Featuring 7 free Review articles on the role of dendritic cells in metabolism, cancer, and immunity, and more.

Read the issue for free here ➡️ tinyurl.com/2zw4znee

#dendriticcells #immunology @fandreata.bsky.social

💊From gene discovery to life-changing therapies, #CysticFibrosis is a triumph of translational science! Read about new successes in CFTR modulators & gene therapy:
febs.onlinelibrary.wiley.com/doi/10.1002/... #CF #PrecisionMedicine

🎉🎖️We congratulate 🌟Jesús Daniel Gómez-Zepeda (IDIBAPS, Barcelona, Spain) on winning the FEBS Letters #PosterPrize at the @biochemsoc.bsky.social meeting on small #Gproteins, recently held in Manchester, UK! 🎉👏👏👏

#SGP25 #Gproteins25

How does the multidrug efflux transporter #Pglycoprotein affect the plasma #membrane? 🤔

In a new study published in @FEBS_Letters, Burkhard Tümmler et al. report that P-glycoprotein modulates the fluidity gradient.

Read the full open access article here ➡️ tinyurl.com/y8zn35eh

⚔️ T cells vs. B-cell tumors—who wins? Single-cell technology elucidates roles in pathogenesis, progression, and therapeutic response 💊 febs.onlinelibrary.wiley.com/doi/10.1002/...
#CancerImmunology #SingleCell #Lymphoma

In our latest issue! Zhizhi Wang and colleagues at ShanghaiTech University describe a new chemically-induced dissociation system for regulating protein-protein interactions in the #endoplasmicreticulum.
Read the article here ➡️ tinyurl.com/y56zfxv3

Niemann-Pick type C (#NPC) disease is a lysosomal storage disorder. In a new article published in FEBS Letters, Andrés D. Klein et al. report genomic modifiers of neurological resilience in an NPC family.

Read it here ➡️ shorturl.at/LHifM

#NiemannPick #Mitochondria #Biomarkers

We are thrilled to release the 2026 programme of events hosted by @events.embl.org and ourselves. Which course are you most excited about?

#biology #molecularbiology #computationalbiology #datascience #bioinformatics

🧬🔍🖥️🔬🦠🧫

@ebi.embl.org
@embl.org

Check out our latest Graphical Review on the mechanisms and kinetic assays of aminoacyl-tRNA synthetases; perfect for printing and display in the lab!

Read (and print!) it here ➡️ shorturl.at/OubXk

#aminoacyltRNAsynthetases

The G74S mutation in cytoskeletal β-#actin, associated with Baraitser–Winter cerebrofrontofacial syndrome (#BWCFF), disrupts SETD3-mediated methylation.
Read the full article here ➡️ doi.org/10.1002/1873...

Our July issue is online now! 🌞
Featuring a Review on how #miRNAs coordinate #metabolism and #immune responses, and research into #Brucella pathogenesis, zinc binding of TLRs, insights into how the multispecific antibody G2 binds to different peptides, and more.

Online here➡️ tinyurl.com/ux99jr7j

🧬 What role do extracellular #histones play in #sepsis? Key mediators and biomarkers—promising for diagnosis & prognosis! 🧪Read more: shorturl.at/MMEl2

How does the #MGITech #sequencing platform compare to #Illumina?

New article here ➡️ tinyurl.com/jd8mykwe

🎉We congratulate 🌟Satoshi Takenaka 🌟 (Institute of Science Tokyo) on winning the FEBS Letters overall #PosterPrize at #FEBS2025 in Istanbul 🌇🌉!

We wish you all the best, Satoshi! 🎉👏👏👏

@febspress.bsky.social

Goodbye Istanbul! 👋 We had an amazing time at the 49th #FEBS2025 Congress 😊
Miss the science already? Check out the Congress Virtual Issue for more great research! 🔬 #ScienceCommunity
lnkd.in/ePPmziHM

Thank you for the interesting article!

We were delighted to see so many people at the FEBS Press session and graphical abstract workshop at #FEBS2025, and would like to thank Dr. Matteo Oliverio for sharing his expertise! 👩‍🎨 👨‍🎨

Look out for the accompanying article, to be published soon! 📜

#IstanbulCats #ScienceArt #GraphicalAbstracts

Starting now at #FEBS2025 ! The FEBS Letters Award Lecture given by Dr. Arno Alpi: SKDEAS intellectual disability syndrome: Pathogenic mechanism revealed by an impaired E3 ubiquitin ligase. We hope to see you there! 😊

#ubiquitin #genetics

Day 5 at hashtag#FEBS2025! 😊 Don’t miss our FEBS Press session (with Dr. Matteo Oliverio's talk on preparing a Graphical Abstract) and Dr. Aron Alpi’s talk on SKDEAS intellectual disability syndrome—FEBS Letters Award Lecture! 🧠
#ubiquitin #Genetics #ScientificArt #GraphicalAbstracts #IstanbulCats

🎉At #FEBS2025 in Istanbul,
the FEBS Letters #PosterPrize on Tuesday, July 08th was awarded to 🌟Melinda Rostás🌟(University of Debrecen, Hungary) for her work on #AdenosineReceptors in obesity!

🎉Congratulations, Melinda! 👏👏👏

@febspress.bsky.social

Explore chromosomal R-loops with Lóránt Szekvolgyi—his talk starts soon! 🧬
Dive deeper with his Perspective article: tinyurl.com/2kjphmva
😊 #Genomics #Rloops #FEBS2025