bioRxiv Bioengineering

Reproducibility and reliability of Free-Water-corrected Diffusion Tensor Imaging of the brain: Revisited https://www.biorxiv.org/content/10.1101/2025.08.06.668995v1

Engineering single-AAV CRISPR-Cas13 RNA base editors for treatment of inherited retinal diseases https://www.biorxiv.org/content/10.1101/2025.08.06.668808v1

Rational MRI Coil Design: An Optimization Framework for the Design of Radiofrequency Coils for Magnetic Resonance Imaging https://www.biorxiv.org/content/10.1101/2025.08.04.668545v1

Targeted analysis of chondrocyte central metabolites in response to cyclical compression and shear deformations https://www.biorxiv.org/content/10.1101/2025.08.04.668582v1

Nanopore-Based Glycan Sequencing via Fragmentation-Reassembly Strategy https://www.biorxiv.org/content/10.1101/2025.08.04.668447v1

Biphasic Mechanical Loading Disrupts Cytoskeletal Symmetry in 3D Architected Scaffolds https://www.biorxiv.org/content/10.1101/2025.08.04.668203v1

Label-Free Longitudinal Imaging of Single Cell Drug Response with a 3D-Printed Cell Culture Platform https://www.biorxiv.org/content/10.1101/2025.08.02.668298v1

Superresolution imaging of live samples by centroid reassignment microscopy https://www.biorxiv.org/content/10.1101/2025.08.03.668310v1

Development of high-affinity, single-domain protein binders for neutralizing household allergens https://www.biorxiv.org/content/10.1101/2025.08.03.668213v1

Single pointwise samples of electric field on a neuron model cannot predict activation threshold by brain stimulation https://www.biorxiv.org/content/10.1101/2025.07.31.667968v1

Cellular-resolution OCT reveals layer-specific retinal mosaics and ganglion cell degeneration in mouse retina in vivo https://www.biorxiv.org/content/10.1101/2025.08.01.668001v1

Barrier Function of the Extracellular Matrix in AAV Gene Therapy https://www.biorxiv.org/content/10.1101/2025.08.01.668133v1

A Microfluidic Platform for Whole-Membrane Integrity Profiling in Live Neuronal Cells https://www.biorxiv.org/content/10.1101/2025.08.02.668278v1

Accelerated Discovery of Aptamer Beacons via Massively Parallel Screening https://www.biorxiv.org/content/10.1101/2025.07.31.667975v1

TRACC-PHYSIO: Time-domain Resolution-Aligned Cross-Correlation to estimate PHYSIOlogical coupling and time delays in dynamic MRI https://www.biorxiv.org/content/10.1101/2025.08.01.668145v1

Growth-factor ligand functionalization enhances cellular and in vivo uptake of DNA nanodevices https://www.biorxiv.org/content/10.1101/2025.08.01.668157v1

Determine Interaction Affinity Changes of the SUMO E1 Activating Enzymes During SUMO Activation using Quantitative FRET technology https://www.biorxiv.org/content/10.1101/2025.07.30.667747v1

MFC-MEC Coupled System for Biohydrogen Production https://www.biorxiv.org/content/10.1101/2025.07.30.667648v1

3D-Printed Scaffolds Encapsulating Red Blood Cell Extracellular Vesicles for MicroRNA Delivery https://www.biorxiv.org/content/10.1101/2025.07.31.667777v1

Pressure Points: Endothelial Responses to Shear Stress and Pressure in Health and Pulmonary Arterial Hypertension https://www.biorxiv.org/content/10.1101/2025.07.28.666693v1

Label-free Tracking of Subcortical White Matter Degradation In Vivo Using Third Harmonic Generation Microscopy in a Mouse Model of Multiple Sclerosis https://www.biorxiv.org/content/10.1101/2025.07.31.667796v1

Spinning disk confocal microscopy with a 25 Megapixel Camera https://www.biorxiv.org/content/10.1101/2025.07.30.667773v1

Epicardial extracellular vesicles modulate gene expression following ischemia-reperfusion injury in heart-on-a-chip https://www.biorxiv.org/content/10.1101/2025.07.31.667965v1

Community Challenge towards Consensus on Characterization of Biological Tissue: C4Bios First Findings https://www.biorxiv.org/content/10.1101/2025.07.30.663632v1

Single-gene knockout of RNLS or HIVEP2 are insufficient to protect β-cell spheroids from allo- and xeno-rejection https://www.biorxiv.org/content/10.1101/2025.07.30.667633v1

Design Guidelines for Dry Electrode Tip Geometry in Electroencephalography Measurements: A Proposal Based on the Scalp's Mechanical Response https://www.biorxiv.org/content/10.1101/2025.07.30.667786v1

Bio-Inspired Ultrasound-Driven Ultrafast Soft Microgripper https://www.biorxiv.org/content/10.1101/2025.07.30.667446v1

Single Capture Quantitative Oblique Back-Illumination Microscopy https://www.biorxiv.org/content/10.1101/2025.07.29.667497v1

Determine Protein Interaction Affinity without Purification Reveals a Two-enzyme Co-recognition of SUMOylation Substrate using Quantitative FRET (qFRET) Technology https://www.biorxiv.org/content/10.1101/2025.07.29.667540v1

A novel sweeping antibody exhibits efficient clearance of the cancer- and autoimmunity-associated cytokine interleukin 16 https://www.biorxiv.org/content/10.1101/2025.07.29.666814v1