bioRxiv Bioengineering

Gut Delivery of Pentameric GLP-1 Using Genetically Engineered Bacillus subtilis for Diabetes and Obesity Treatment https://www.biorxiv.org/content/10.1101/2025.10.07.680898v1

Engineering C3.5 Photosynthesis: Coupling Mitochondrial Bioenergetics to Rubisco Efficiency in Arabidopsis https://www.biorxiv.org/content/10.1101/2025.10.04.680431v1

Continuous Production of Recombinant Adeno-Associated Virus in the Insect Cell/Baculovirus Expression Vector System https://www.biorxiv.org/content/10.1101/2025.10.06.680831v1

Enhancing Volatile Fatty Acid Accumulation in Seaweed-Arrested Anaerobic Digestion via a Two-Tier Framework of Engineering Diagnostics and Microbial Surveillance https://www.biorxiv.org/content/10.1101/2025.10.06.680780v1

Mycoelectronics: Bioprinted Living Fungal Bioelectronics for Artificial Sensation https://www.biorxiv.org/content/10.1101/2025.10.06.680560v1

A yeast mating-based platform enables the generation and screening of ultra large antibody libraries https://www.biorxiv.org/content/10.1101/2025.10.06.680701v1

Understanding Virtual Staining with generative adversarial networks for Osteoclast Imaging https://www.biorxiv.org/content/10.1101/2025.10.06.679965v1

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System https://www.biorxiv.org/content/10.1101/2025.10.06.680733v1

From human joints to bioreactor setups: quantifying mechanical stimuli in cartilage physiology and regeneration https://www.biorxiv.org/content/10.1101/2025.10.06.678667v1

In Vivo Metabolic Tagging and Targeting of Circulating Red Blood Cells https://www.biorxiv.org/content/10.1101/2025.10.05.676041v1

Matrix stiffness induces endothelial network senescence https://www.biorxiv.org/content/10.1101/2025.10.05.680536v1

Optimization of velocity receptor transduction in CAR T cells https://www.biorxiv.org/content/10.1101/2025.10.05.680548v1

The Effective Inertia of the Lower Limb During Locomotion https://www.biorxiv.org/content/10.1101/2025.10.03.680415v1

Design and Synthesis of Peptide-Polyester Conjugates for Cell-Mediated Scaffold Degradation https://www.biorxiv.org/content/10.1101/2025.10.06.680674v1

RamanBot: Versatile high throughput Raman system https://www.biorxiv.org/content/10.1101/2025.10.03.680377v1

Bioengineered human tonsil organoids as an immuno-engineering platform for evaluating immune functions https://www.biorxiv.org/content/10.1101/2025.10.04.680210v1

Multi-immersion Oblique Plane Microscope (miOPM): A reconfigurable platform for high-resolution Light-Sheet Fluorescence Microscopy. https://www.biorxiv.org/content/10.1101/2025.10.04.680473v1

In Silico Optimisation of Regenerative Cell Therapy in the Infarcted Human Ventricles to Mitigate Arrhythmic Burden https://www.biorxiv.org/content/10.1101/2025.10.03.680241v1

Systemic tumor-targeting gene drive vectors proactively eliminate drug resistance in solid tumors https://www.biorxiv.org/content/10.1101/2025.10.04.680477v1

Hierarchical Coarse-to-Fine cGAN for Subtype-Specific Freezing of Gait Signal Generation https://www.biorxiv.org/content/10.1101/2025.10.04.680444v1

Machine Learning-assisted Raman Spectral Analysis of Serotonin-responsive ssDNA-SWCNT Nanosensor for Improved Selectivity against Dopamine https://www.biorxiv.org/content/10.1101/2025.10.02.679925v1

Mechanical Fingerprints in Breast Cancer Research: A Multimodal Experimental Approach https://www.biorxiv.org/content/10.1101/2025.10.03.680332v1

A Micro-Engineered Heart Tissue Model of Desmin-related Cardiomyopathy Caused by Mutant αB Crystalin https://www.biorxiv.org/content/10.1101/2025.10.02.680018v1

Development of a Serum-Free Producer Cell Line Generation Process for Scalable and Efficient rAAV Production for gene therapy applications https://www.biorxiv.org/content/10.1101/2025.10.02.679972v1

miniVec: A miniaturized plasmid backbone supporting antibiotic-free and additive-free fermentation with enhanced yield and functionality https://www.biorxiv.org/content/10.1101/2025.10.02.679775v1

Multiscale Computational Modeling of the Cardiopulmonary Consequences of Postnatal Hyperoxia with Implications for Preterm Born Children https://www.biorxiv.org/content/10.1101/2025.10.01.679825v1

Flow Autoencoders are Effective Protein Tokenizers https://www.biorxiv.org/content/10.1101/2025.10.01.679645v1

Nanochirality-programmed Type-I photosensitizer enables deep-tumor photodynamic therapy by reducing extracellular-matrix adhesion https://www.biorxiv.org/content/10.1101/2025.10.01.679807v1

Precision Glycoform Engineering: Combining plant and in vitro systems for tailored biopharmaceutical production https://www.biorxiv.org/content/10.1101/2025.10.01.679750v1

Vis-OCT Explorer: an open-source software for visible-light optical coherence tomography data processing https://www.biorxiv.org/content/10.1101/2025.10.01.679626v1