bioRxiv Biophysics

Mathematical Model for the Progression of Rhegmatogenous Retinal Detachment (RRD) https://www.biorxiv.org/content/10.1101/2025.08.03.668360v1

Simulation-Guided Exploration of PAINT Parameter Space for Accurate Molecular Quantification https://www.biorxiv.org/content/10.1101/2025.08.04.668137v1

Mycobacterial DNA-binding protein 1 (MDP1) induces RNA condensation as revealed by high-speed AFM https://www.biorxiv.org/content/10.1101/2025.08.03.668364v1

Scaling down protein language modeling with MSA Pairformer https://www.biorxiv.org/content/10.1101/2025.08.02.668173v1

Effectiveness of Outer Hair Cells as Cochlear Amplifier: Coupled Oscillator Models https://www.biorxiv.org/content/10.1101/2025.08.02.668240v1

The molecular mechanism of lipid uptake by membrane-anchored bridge-like lipid transfer proteins. https://www.biorxiv.org/content/10.1101/2025.08.01.668188v1

Hierarchically ordered multi-timescale structural dynamics of the intrinsically disordered p53 transactivation domain https://www.biorxiv.org/content/10.1101/2025.08.01.668138v1

Transition Metal Binding Drives Folding of a Metalloregulatory Riboswitch by Modulating Conformational Flexibility at Helical Junctions https://www.biorxiv.org/content/10.1101/2025.08.02.668262v1

Global excitatory synchrony: Ketamine induces global common-mode excitatory network oscillation by decoupling key interneurons https://www.biorxiv.org/content/10.1101/2025.08.02.667727v1

Study on the interaction of Yohimbine with duplex oligonucleotide using spectroscopic and computational tools https://www.biorxiv.org/content/10.1101/2025.07.31.667832v1

EphA2 and Ephrin-A1 Use the Same Interface for Both in cis and in trans Interactions That Regulate Distinct Cell Signaling and Function https://www.biorxiv.org/content/10.1101/2025.07.31.667925v1

How Well Do Molecular Dynamics Force Fields Model Peptides? A Systematic Benchmark Across Diverse Folding Behaviors https://www.biorxiv.org/content/10.1101/2025.07.31.667969v1

Membrane Transport of Rhodamine 6G by the reconstituted multidrug resistance ABC transporter Pdr5 in Horizontal Lipid Bilayer https://www.biorxiv.org/content/10.1101/2025.07.31.667618v1

Braess' Paradox in Enzyme Kinetics: Asymmetry from Population Balance without Direct Cooperativity https://www.biorxiv.org/content/10.1101/2025.07.30.667590v1

NEXT-FRET: A solution-based smFRET platform to resolve folding intermediates under native conditions https://www.biorxiv.org/content/10.1101/2025.07.30.666321v1

Lipid monolayers adsorbing mRNA as models for mRNA enclosed in lipid nanoparticles for transfection https://www.biorxiv.org/content/10.1101/2025.08.01.667014v1

Multiplexed quantum sensing reveals coordinated thermomagnetic regulation of mitochondria https://www.biorxiv.org/content/10.1101/2025.07.30.666664v1

Localisation of Apicomplexa motor Myosin A with axial nanometric precision using graphene energy transfer https://www.biorxiv.org/content/10.1101/2025.07.30.667387v1

Metabolic Rigidity as a Mechanical Barrier to Malaria: Flickering Loss in PKLR-Deficient Erythrocytes https://www.biorxiv.org/content/10.1101/2025.07.29.667448v1

Does Human Transthyretin Aggregate in Blood Plasma or in Cardiac Tissue? A Mathematical Modeling Study https://www.biorxiv.org/content/10.1101/2025.07.29.667417v1

A molecular switch in NAC prevents mitochondrial protein mistargeting by SRP https://www.biorxiv.org/content/10.1101/2025.07.29.667405v1

An Allosteric Model for Electromechanical Coupling in Cardiac CNBD Channels https://www.biorxiv.org/content/10.1101/2025.07.28.666606v1

Native Ion Mobility-MS Reveals the Bead Ejection Mechanism in Multi-Domain Nucleic Acids https://www.biorxiv.org/content/10.1101/2025.07.29.667413v1

MDZip: Neural Compression of Molecular Dynamics Trajectories for Scalable Storage and Ensemble Reconstruction https://www.biorxiv.org/content/10.1101/2025.07.31.667955v1

An antiparallel cell circulation driven by self-alignment induces phase separation https://www.biorxiv.org/content/10.1101/2025.07.28.667323v1

Tau hyperphosphorylation impairs cooperative binding tomicrotubules and perturbs organelle trafficking in neurons https://www.biorxiv.org/content/10.1101/2025.07.31.667882v1

Precise 3D Tracking of Highly Non-planar Eukaryotic Flagellar Beating Patterns using Digital Holographic Microscopy https://www.biorxiv.org/content/10.1101/2025.07.28.666810v1

Assessing cellular metabolic dynamics with NAD(P)H fluorescence polarization imaging https://www.biorxiv.org/content/10.1101/2025.07.28.667273v1

About the alignment and 3D reconstruction of sparse cryo-scanning transmission electron tomography datasets https://www.biorxiv.org/content/10.1101/2025.07.28.667105v1

Cytoplasmic crowding acts as a porous medium reducing macromolecule diffusion https://www.biorxiv.org/content/10.1101/2025.07.28.667145v1