Tempera_Lab

Integrated transcriptomic and methylome analysis reveals retinoic acid pathway activation after decitabine treatment in EBV-associated gastric cancer | mBio EBV+ gastric cancer contains hypermethylated DNA, and despite this distinct molecular phenotype, there are currently no Epstein–Barr virus (EBV)-specific treatments available. Using an FDA-approved in...

Excited to share our new study: Integrated transcriptomic and methylome analysis reveals retinoic acid pathway activation after decitabine treatment in EBV-associated gastric cancer | mBio #EBV #Epigenetics #CancerResearch #GastricCancer #DNAme #Transcriptomics
journals.asm.org/doi/10.1128/...

Honored and grateful to be promoted to Professor. Thank you to the mentors, colleagues, students, and collaborators who made this possible.

Integrated transcriptomic and methylome analysis reveals retinoic acid pathway activation after decitabine treatment in EBV associated gastric cancer Epstein-Barr virus associated gastric cancer (EBVaGC) accounts for ∼9–10% of gastric cancers worldwide and is defined by a distinctive molecular profile, including extreme hypermethylation of the DNA....

🧬 New from our Lab!
Integrated transcriptomic + methylome profiling reveals that Decitabine activates the retinoic acid pathway in EBV-associated gastric cancer, uncovering how DNA demethylation reshapes viral–host signaling.

#Epigenetics #EBV #CancerResearch
www.biorxiv.org/content/10.1...

Thank you

EBNA leader protein orchestrates chromatin architecture remodeling during Epstein-Barr virus-induced B cell transformation Abstract. Epstein-Barr virus Nuclear Antigen Leader Protein (EBNA-LP) plays a pivotal role in the transformation of B cells by Epstein-Barr virus (EBV), fu

We are excited to share our recent work:
EBNA leader protein orchestrates chromatin architecture remodeling during Epstein-Barr virus-induced B cell transformation url: academic.oup.com/nar/article/...

RFK Jr. comes ‘home’ to his anti-vaccine group, commits to ‘a break’ for U.S. infectious disease research He has suggested without evidence that researchers and pharmaceutical companies are driven by profit to neglect chronic conditions.

RFK Jr.: “Thank you [to the NIH] for public service. We’re going to give infectious disease a break for about eight years.”

Kennedy wants to take a “break” from studying infectious diseases like COVID-19 and measles.

www.nbcnews.com/politics/pol...