Samaneh Chaharmiri

Yet another new function of bile acids -and relevance of the microbiome in regulating the efficacy of medications.
#microbiome #IBD. Discovered using #metabolomics repository scale analysis.
#opendata Thanks to all the collaborators and Vincent for leading it. www.biorxiv.org/content/10.6...

I am super excited that our paper on inter-laboratory comparability of non-targeted LC–MS/MS analysis of dissolved organic matter was just published in ES&T.

pubs.acs.org/doi/10.1021/...

Inspiring the next generation of plant scientists: What we learned from 421 plant biologists Addressing biodiversity and climate crises requires a new generation of plant scientists, yet interest in plant-related careers is declining globally. A survey of 421 plant biologists revealed that t...

nph.onlinelibrary.wiley.com/doi/10.1002/...

The underappreciated diversity of bile acid modifications Using mass spectrometry-based tools to mine public untargeted MS/MS data revealed the vastly underappreciated diversity of bile acids hidden in plain sight and led to the discovery of previously unkno...

The best keychain ever - ty. This was a molecule discovered in this work www.cell.com/cell/fulltex... . To Prof. Ipsita - I can’t wait to see what you will discover in your own lab at Penn State. Such a pleasure to have had you as a co-worker in the lab. @ipsitamohanty.bsky.social

Great work👌👌

This is an important paper to read for people that are trying to understand metabolomics data. Ions detected (features) are not molecules and molecules will generate many ion forms. Be aware of MS ion forms - understand and leverage them. Dark metabolome has a lot of discovery potential.

Photo of Carolina Coelho, and the text "BMS Talk 10 December 2025 19:30-21:00. Crossing the line: visualising how Cryptococcus neoformans breaches host tisue barriers from lung to brain."

Cryptococcus neoformans is responsible for nearly 200,000 deaths per year - more than any other fungal pathogen. In this talk, Caroline Coelho describes development of a large-scale imaging platform to investigate host-pathogen interactions
👉 Book here: www.britmycolsoc.org.uk/bms-talks.html

#mushroom
#lichen
#wood
#lovely_fungi

🌺🌺🙏🙏

😍😍😍#mushrooms

We are delighted to sponsor the Natural Products in the 'Omics Era' symposium at @pacifichem.bsky.social!

Keynote speakers include @pieterdorrestein.bsky.social whose research focuses on new MS-based methods to understand the chemistry of microbes #ORG018

📅19-20 December 2025
🔗pacifichem.org

@markowenmartin.bsky.social shares how his students test moss- and lichen-derived bacteria for antibiotic activity, using Micrococcus luteus as a control

Except from Matters Microbial 116: Microbes in the Concrete Instead of the Abstract

🚨 CMM LATAM Unit website is now live 🚨

Explore the CMM LATAM unit, established by University of São Paulo, Brazil and the MRC Centre for Medical Mycology (CMM).

🌍 Explore cutting edge research
🎓 Discover funding and training opportunities
🛡️ Join the FAILSAFE network

cmm-latam.com

From Mass to Class: Classification of Amphetamines MS/MS Spectra via Graph Neural Networks Identifying emerging novel psychoactive substances (NPS), using liquid chromatography high-resolution tandem mass spectrometry (LC-HR-MS/MS), is often hindered by their frequent absence from mass spec...

From Mass to Class: Classification of Amphetamines MS/MS Spectra via Graph Neural Networks #JCIM pubs.acs.org/doi/10.1021/...

Pseudomonas aeruginosa senses exopolysaccharide trails using type IV pili and adhesins during biofilm formation - Nature Microbiology Opposing forces generated by exopolysaccharide trail binding versus type IV pilus retraction generate a high cyclic diGMP–high cyclic AMP state in Pseudomonas aeruginosa that promotes social motility.

Cool 🦠

William Schmidt
Gerard Wong Lab @UCLA
Nature Microbiology

Pseudomonas aeruginosa lays down Psl exopolysaccharide as it crawls

Other cells detect and follow these trails using type IV pili pulling against adhesins like CdrA triggering c-di-GMP & cAMP surges to shift into early biofilm mode

Analysis of bioactive compounds in Gardenia jasminoides from different regions by UFLC/QTRAP-MS and PCA #Medicine journals.lww.com/md-journal/f...

HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics Single-cell metabolomics (SCM) can probe metabolic heterogeneity but is hindered by low sensitivity for small molecules, limited scalability, and the lack of standardized frameworks for data analysis....

HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics #Cell #MassSpec www.cell.com/cell/fulltex...

We are looking for a 3-year postdoc to work with Daniel Probst, Justin van der Hooft and myself on an exciting project involving federated learning and integrative omics for discovery of new antibiotics from natural products.
Apply here: www.wur.nl/en/vacancy/p...
Please share!

It started with a concept of using data science and mass spectrometry for drug discovery with the goal to help people improve quality of their lives enveda.com. Now it’s a 🦄 that is getting a real shot at doing so with great clinical leads and in clinical trials www.youtube.com/watch?v=VafS....

Interested in a co-authorship?
We’re building a tool for repository-scale untargeted #metabolomics and #exposomics of #environmental data. To make it the best it can be, we’re looking for people willing to share high-resolution LC-MS/MS (DDA) data from #water, #soil, #sediment, and related samples.

Vitamin auxotrophies shape microbial community assembly on model marine particles Abstract. Microbial community assembly is governed by the flow of carbon sources and other primary metabolites between species. However, central metabolism

🌊🦠🧪 Delighted to share this work now out in @isme-microbes.bsky.social: doi.org/10.1093/isme... The currency of microbial life is chemistry, but there’s so much still unknown about how metabolic interactions shape communities. 1/

Yes reach out to Yasin for this project. It will allow a worldwide picture of the environmental metabolome. This can be already published or not yet published data but will need world coordinates.

Lactobacillus acidophilus promotes cognitive function recovery via regulating microglial peroxisomal function in cerebral ischemia Huang et al. report that L. acidophilus deficiency correlates with cognitive decline in cerebral ischemia patients. In cerebral ischemia mouse models, L. acidophilus supplementation enhances linoleic ...

🄰
🄿🅁🄾🄱🄸🄾🅃🄸🄲
🄵🄾🅁
🅂🅃🅁🄾🄺🄴
🅁🄴🄲🄾🅅🄴🅁🅈 ??

Low 𝘓𝘢𝘤𝘵𝘰𝘣𝘢𝘤𝘪𝘭𝘭𝘶𝘴 𝘢𝘤𝘪𝘥𝘰𝘱𝘩𝘪𝘭𝘶𝘴 levels in the gut predicted cognitive decline after ischemic stroke

Probiotic supplementation improved cognition in mice + human clinical trial by ↑ linoleic acid uptake → microglial peroxisomes → anti-inflammatory reprogramming

The best of both worlds with awesome speakers that will focus on how the microbiome affects ecosystems at a mechanistic level. Can’t wait for this meeting.

A diverse and distinct microbiome inside living trees - Nature Microbiome analyses of living trees show that a single tree can host approximately one trillion bacteria, with microbial communities distinctly partitioned between heartwood and sapwood and with minim...

#NatMicroPicks

Hidden microbial world in trees🌳

Living wood hosts trillions of bacteria making trees a complex ecosystems with major roles in forest health and function.

#PlantMicro #MicroSky

www.nature.com/articles/s41...

taxburst v0.3.0 is now released - this is an update of the Krona visualization system for microbiome/metagenome taxonomy analyses. Enjoy!