Naomi McGovern

This is a second video shows Listeria monocytogenes (green) recruiting host cell actin (red) in term Hofbauer cells. Created by Nagisa Yoshida

Here is a video from our manuscript capturing Hofbauer cells interacting with each other in placental villi explants

Interactions between placental Hofbauer cells and L. monocytogenes change throughout gestation Gestational changes in Hofbauer cells alter their interactions with Listeria monocytogenes.

Happy share this latest study from the team. Here we look at placental macrophage biology across pregnany and their interaction with Listeria monocytogenes.
www.science.org/doi/10.1126/...

Congrats!

Congratulations to @drbmalengier.bsky.social, @magmarlene.bsky.social and Team Gentek of @edinuni-irr.bsky.social for this amazing tour de force, comprehensively characterising #synovial #macrophage #development 💪🏻

Thanks for visiting and your great talk. See you soon

‘It’s been a tough period’: NIH’s new director speaks with Science Jay Bhattacharya discusses staff morale, grant cuts, and “rumors”

NIH’s new director Jay Bhattacharya discusses staff morale, grant cuts, and “rumors” in an interview with Science. scim.ag/4mhSMpA

Want to join us in the field of placental biology? Check out this postdoc position available in my lab in collaboration with Catherin Aiken.
Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge

IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis Immune-microbiota interactions are required to maintain host homeostasis. Kim et al. identified that steady-state sensing of IL-10 by interstitial macrophages (IMs) prevents spontaneous lung inflammat...

Thrilled to share that our paper is now published in Immunity @cp-immunity.bsky.social ! 🎉 It’s been a long journey, and I’m incredibly grateful to all my co-authors—especially Dr. Teruyuki_Sano—for your dedication. This wouldn’t have been possible without you!
www.cell.com/immunity/ful...

Want to join us in the field of placental biology? Check out this postdoc position available in my lab in collaboration with Catherin Aiken.
Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge

Fascinating article

The genetic architecture of and evolutionary constraints on the human pelvic form Human pelvic evolution following the human-chimpanzee divergence is thought to result in an obstetrical dilemma, a mismatch between large infant brains and narrowed female birth canals, but empirical ...

A new Science study reveals genetic links between pelvic structure and function, locomotion, and childbirth outcomes.

The findings offer fresh insights into how our species evolved to balance the competing demands of bipedalism and childbirth. scim.ag/3Y2lQHb

Excitied about this meeting in July with a great line up of speakers.

🔬 Does your research explore placental ageing, senescence, prolonged pregnancy, or term complications like pre-eclampsia?

Join leading experts at our Annual Meeting! Registration open, don’t miss your chance to be part of the discussion.

www.trophoblast.cam.ac.uk/ctrconferenc...

How Trump is following Project 2025’s radical roadmap to defund science Much of the Trump administration’s agenda for research is laid out in the 900-plus-page blueprint. Nature read it so you don’t have to.

Much of the Trump administration’s agenda for research is laid out in the 900-plus-page Project 2025. Nature examines science-related policies from Project 2025 that have already come to pass, and which ones might be on the horizon. 🧪

Great to see the abstracts start to come in for EMDS2025.

We have over 20 short talk slots up for grabs - with dedicated slots for #ECRs (PhD and postdocs). So, if you want to showcase your work to Europe's #macrophage #monocyte and #dendriticcell community, be sure to submit your abstract ASAP.

Today I lost an NIH grant training clinicians to do research about intimate partner violence with perinatal women.

More women are murdered in the perinatal period than die of obstetric complications.

I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.

Rare genetic disorder treated in womb for the first time The child, who is now almost three years old, shows no signs of the often fatal motor neuron disease.

New research shows that treatment of a rare and often fatal neurodegenerative condition in utero has been a success with the child still symptom free at 2 and a half years. 🧪

The Loke CTR team have worked hard on laboratory sustainability and efficiency and have been awarded LEAF Bronze status as a result!

More about LEAF (Laboratory Efficiency Assessment Framework) www.ucl.ac.uk/sustainable/...

We welcomed @margaridamcm.bsky.social to Cambridge last week. Margarida presented her talk 'The evolution of new cell types and organs: the view from the placenta'. We are very grateful to her for spending the day with us, meeting colleagues and presenting her fascinating research.

‘Dark proteins’ hiding in our cells could hold clues to cancer and other diseases The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do.

The human genome encodes potentially thousands of tiny proteins that were previously overlooked. Nature reports on the search to find out what they do. 🧪

Congrats Charlotte and team!

Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair scRNA-seq has uncovered ontogenically distinct hepatic macrophage populations, but their functions remain unclear. Here, De Ponti et al. identify recruited LAMs and resident LAM-like KCs in multiple l...

With my first Bluesky post, I am very happy to share our latest study led by PhD student Federico De Ponti and postdoc Ania Bujko www.cell.com/immunity/ful...

For anyone following here who's not seen this on our other channels, closing date for the Loke CTR Next Generation Fellowship is 31 Jan 2025, details here www.trophoblast.cam.ac.uk/next-generat...

Feel free to share in your networks!

Congrats!!

Congrats to Ashley on this prestigious award www.path.cam.ac.uk/news/profess...

‼️ SAVE THE DATE

The next EMDS Meeting will take place from 16-18th Sept. 2025 in majestic Edinburgh 🏴󠁧󠁢󠁳󠁣󠁴󠁿. If you love macs, monos &/or DCs, or just want to learn more about them, THIS is the meeting for you.

Space limited - so watch out for details.
@britsocimm.bsky.social

Origin, fate and function of extraembryonic tissues during mammalian development - Nature Reviews Molecular Cell Biology During mammalian embryogenesis, extraembryonic tissues are required for the patterning and morphogenesis of the embryo. This Review discusses how signalling networks and epigenetic modifications regul...

Beautiful review from Courtney Hanna @cwhanna.bsky.social and team.
Now Online: Origin, fate and function of extraembryonic tissues during mammalian development go.nature.com/3OELOeK

#EMDS2024 was brilliant. Thx to all the organisers. Planning is well underway for EMDS25: Scotland Edition. We look forward to welcoming you to beautiful Edinburgh next year.

👀 for details in the coming months.

@britsocimm.bsky.social @cytokinesociety.bsky.social @societymucosalimm.bsky.social