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Naomi McGovern

@mcgovernlab.bsky.social

Mononuclear phagocytes in health, disease and pregnancy

111 Followers  |  138 Following  |  15 Posts  |  Joined: 07.08.2024  |  1.8435

Latest posts by mcgovernlab.bsky.social on Bluesky

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Calling all postdocs / early career researchers! The Loke CTR Next Generation Fellowship is a stepping stone to research independence!

Visit ๐Ÿ”— www.trophoblast.cam.ac.uk/next-generat...

Need guidance to find a research sponsor? Register your interest via our short form forms.office.com/e/vST36RSB96

30.10.2025 17:31 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Looking to pursue cutting-edge research in early development, maternal-fetal interaction, or placental biology? See ๐Ÿ‘‡

- Funded PhD www.trophoblast.cam.ac.uk/phd-students...
- Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat...
- MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...

02.10.2025 08:15 โ€” ๐Ÿ‘ 9    ๐Ÿ” 14    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
Next Generation Fellowship Overview | Loke Centre for Trophoblast Research Next Generation Fellowships The Loke Centre for Trophoblast Research has an established highly-successful program to fund and mentor Next Generation Research Fellowships.

Applications are open for the Next Generation Fellowship โ€“ applications until 30 January 2026 www.trophoblast.cam.ac.uk/next-generat...

02.10.2025 08:40 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
PhD Studentships | Loke Centre for Trophoblast Research The Loke Centre for Trophoblast Research (Loke CTR) offers fully-funded 4-year PhD studentships for home or overseas students The Loke Centre for Trophoblast Research (Loke CTR) provides a dynamic env...

Applications are open! For anyone looking to pursue a PhD in cutting-edge research in early development, maternal-fetal interaction, or placental biology: www.trophoblast.cam.ac.uk/phd-students...

02.10.2025 08:39 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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The mini placentas and ovaries revealing the basics of womenโ€™s health Lab-made organoids that mimic reproductive tissues could point to treatments for common conditions such as pre-eclampsia and endometriosis.

An insight into advances in the field of placental biology and their importance: www.nature.com/articles/d41...

23.09.2025 20:24 โ€” ๐Ÿ‘ 1    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Great to see this out for all to see after a lot of hard work by @lizihegarty.bsky.social and @bainlab.bsky.social. Colonic #macrophages persist but are transcriptionally altered post- #inflammation in a mouse model of #colitis.

22.09.2025 06:48 โ€” ๐Ÿ‘ 9    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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TNF and type I interferon crosstalk controls the fate and function of plasmacytoid dendritic cells - Nature Immunology Plasmacytoid dendritic cells are type 1 interferon (IFN-I)-producing antiviral specialists that have been shown to be able to differentiate into conventional dendritic cells. Here the authors show how...

๐Ÿšจ New in @natimmunol.nature.com : @idoyagalab.bsky.social shows that plasmacytoid DCs can reprogram into cDC2s after TNF-ฮฑ stimulation. Fascinating plasticity!
๐Ÿ‘‡

www.nature.com/articles/s41...

09.09.2025 08:14 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Group Leader Career Development Fellowships - Dunn School Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?

Are you a postdoc interested in the mechanisms of disease?

Do you have a great record and an exciting vision?

Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.

Deadline 30th September...pass it on!

www.path.ox.ac.uk/work-with-us...

01.09.2025 14:39 โ€” ๐Ÿ‘ 65    ๐Ÿ” 67    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 3
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This is a second video shows Listeria monocytogenes (green) recruiting host cell actin (red) in term Hofbauer cells. Created by Nagisa Yoshida

21.07.2025 10:31 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Here is a video from our manuscript capturing Hofbauer cells interacting with each other in placental villi explants

21.07.2025 10:28 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Interactions between placental Hofbauer cells and L. monocytogenes change throughout gestation Gestational changes in Hofbauer cells alter their interactions with Listeria monocytogenes.

Happy share this latest study from the team. Here we look at placental macrophage biology across pregnany and their interaction with Listeria monocytogenes.
www.science.org/doi/10.1126/...

21.07.2025 08:27 โ€” ๐Ÿ‘ 15    ๐Ÿ” 9    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

Congrats!

09.07.2025 13:54 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Congratulations to @drbmalengier.bsky.social, @magmarlene.bsky.social and Team Gentek of @edinuni-irr.bsky.social for this amazing tour de force, comprehensively characterising #synovial #macrophage #development ๐Ÿ’ช๐Ÿป

26.05.2025 20:00 โ€” ๐Ÿ‘ 11    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Thanks for visiting and your great talk. See you soon

13.05.2025 06:58 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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โ€˜Itโ€™s been a tough periodโ€™: NIHโ€™s new director speaks with Science Jay Bhattacharya discusses staff morale, grant cuts, and โ€œrumorsโ€

NIHโ€™s new director Jay Bhattacharya discusses staff morale, grant cuts, and โ€œrumorsโ€ in an interview with Science. scim.ag/4mhSMpA

06.05.2025 13:33 โ€” ๐Ÿ‘ 36    ๐Ÿ” 7    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 5

Want to join us in the field of placental biology? Check out this postdoc position available in my lab in collaboration with Catherin Aiken.
Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge

25.04.2025 15:57 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
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IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis Immune-microbiota interactions are required to maintain host homeostasis. Kim etย al. identified that steady-state sensing of IL-10 by interstitial macrophages (IMs) prevents spontaneous lung inflammat...

Thrilled to share that our paper is now published in Immunity @cp-immunity.bsky.social ! ๐ŸŽ‰ Itโ€™s been a long journey, and Iโ€™m incredibly grateful to all my co-authorsโ€”especially Dr. Teruyuki_Sanoโ€”for your dedication. This wouldnโ€™t have been possible without you!
www.cell.com/immunity/ful...

29.04.2025 15:52 โ€” ๐Ÿ‘ 46    ๐Ÿ” 9    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Want to join us in the field of placental biology? Check out this postdoc position available in my lab in collaboration with Catherin Aiken.
Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge

25.04.2025 15:57 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

Fascinating article

17.04.2025 13:20 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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The genetic architecture of and evolutionary constraints on the human pelvic form Human pelvic evolution following the human-chimpanzee divergence is thought to result in an obstetrical dilemma, a mismatch between large infant brains and narrowed female birth canals, but empirical ...

A new Science study reveals genetic links between pelvic structure and function, locomotion, and childbirth outcomes.

The findings offer fresh insights into how our species evolved to balance the competing demands of bipedalism and childbirth. scim.ag/3Y2lQHb

16.04.2025 16:28 โ€” ๐Ÿ‘ 59    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Excitied about this meeting in July with a great line up of speakers.

16.04.2025 15:07 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ”ฌ Does your research explore placental ageing, senescence, prolonged pregnancy, or term complications like pre-eclampsia?

Join leading experts at our Annual Meeting! Registration open, donโ€™t miss your chance to be part of the discussion.

www.trophoblast.cam.ac.uk/ctrconferenc...

19.03.2025 14:02 โ€” ๐Ÿ‘ 3    ๐Ÿ” 4    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3
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How Trump is following Project 2025โ€™s radical roadmap to defund science Much of the Trump administrationโ€™s agenda for research is laid out in the 900-plus-page blueprint. Nature read it so you donโ€™t have to.

Much of the Trump administrationโ€™s agenda for research is laid out in the 900-plus-page Project 2025. Nature examines science-related policies from Project 2025 that have already come to pass, and which ones might be on the horizon. ๐Ÿงช

04.04.2025 01:07 โ€” ๐Ÿ‘ 60    ๐Ÿ” 30    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2

Great to see the abstracts start to come in for EMDS2025.

We have over 20 short talk slots up for grabs - with dedicated slots for #ECRs (PhD and postdocs). So, if you want to showcase your work to Europe's #macrophage #monocyte and #dendriticcell community, be sure to submit your abstract ASAP.

04.04.2025 05:38 โ€” ๐Ÿ‘ 4    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Today I lost an NIH grant training clinicians to do research about intimate partner violence with perinatal women.

More women are murdered in the perinatal period than die of obstetric complications.

I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.

22.03.2025 00:19 โ€” ๐Ÿ‘ 29057    ๐Ÿ” 9112    ๐Ÿ’ฌ 856    ๐Ÿ“Œ 492
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Rare genetic disorder treated in womb for the first time The child, who is now almost three years old, shows no signs of the often fatal motor neuron disease.

New research shows that treatment of a rare and often fatal neurodegenerative condition in utero has been a success with the child still symptom free at 2 and a half years. ๐Ÿงช

21.02.2025 08:07 โ€” ๐Ÿ‘ 63    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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The Loke CTR team have worked hard on laboratory sustainability and efficiency and have been awarded LEAF Bronze status as a result!

More about LEAF (Laboratory Efficiency Assessment Framework) www.ucl.ac.uk/sustainable/...

12.02.2025 15:27 โ€” ๐Ÿ‘ 8    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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We welcomed @margaridamcm.bsky.social to Cambridge last week. Margarida presented her talk 'The evolution of new cell types and organs: the view from the placenta'. We are very grateful to her for spending the day with us, meeting colleagues and presenting her fascinating research.

10.02.2025 15:11 โ€” ๐Ÿ‘ 4    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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โ€˜Dark proteinsโ€™ hiding in our cells could hold clues to cancer and other diseases The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do.

The human genome encodes potentially thousands of tiny proteins that were previously overlooked. Nature reports on the search to find out what they do. ๐Ÿงช

02.02.2025 17:46 โ€” ๐Ÿ‘ 72    ๐Ÿ” 25    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

Congrats Charlotte and team!

28.01.2025 09:02 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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