#NeuroDegeneration preprints

The effects of nicotine on neurocognitive outcomes: evidence from a polygenic risk score analysis #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.64898/2025.11.27.25341175v1

Phi and Alzheimer's Disease: Is the Tree Drawing Test for diagnosing cognitive impairment an inner view of the golden proportion?” #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8069544/latest

Monopolar network mapping predicts tremor outcomes of deep brain stimulation in Parkinson's disease #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.1101/2025.11.18.25340336v1

Low frequency BOLD oscillations, APOE4, and plasma pTau217 #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.1101/2025.11.25.25340991v1

DeepFLAIR*: Improving Multiple Sclerosis Diagnostic Imaging Workflow Using Deep Learning #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.1101/2025.11.25.25340993v1

Longitudinal functional network connectivity changes across the clinical stages of C9orf72 hexanucleotide repeat expansion carriers #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.1101/2025.11.23.25340528v1

Cortico-Pallidal Beta Dynamics Underlie Impaired Turning in Parkinson's Disease #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.1101/2025.11.25.25340849v1

Cervical atrophy following complete thoracic spinal cord injury: Insights from a multinational cohort #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.1101/2025.11.24.25340899v1

Using Explainable AI to Identify Disease-Relevant and Deep Brain Stimulation Treatment-Sensitive Gait Features in Parkinson's Disease #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.1101/2025.11.27.25341152v1

Neurobiological correlates of longitudinal grey matter volume changes in preclinical Alzheimer's disease #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.64898/2025.12.01.25341227v1

Glucagon-Like Peptide-1 Receptor Agonists and Risk of Parkinsonian Disorders in Patients with Obesity #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.64898/2025.11.24.25340763v1

Understanding the pattern of cognitive decline in GBA1-related Parkinson's Disease: a longitudinal multi-cohort study #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.64898/2025.12.01.25341351v1

Ocrelizumab versus Natalizumab in Relapsing-Remitting Multiple Sclerosis: A Real-World Evidence Study Using Registry-Linked Electronic Health Records #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.64898/2025.12.01.25341331v1

Genome-wide association study of REM-sleep behaviour disorder identifies new risk loci. #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.64898/2025.12.01.25339623v1

A Pathway-Based Machine Learning Approach Identifies Region-Specific Markers and Patterns in Alzheimers Disease Patients Based on Spatial and Severity Metadata #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.64898/2025.12.01.25341417v1

The Protein Disulfide Isomerase P4HB/PDIA1 Modulates PrPC Levels and Prion Replication #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2025.12.01.691611v1

Dual-targeting snRNA gene therapy rescues STMN2 and UNC13A splicing in TDP-43 proteinopathies #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2025.12.01.691001v1

Anterior thalamic nucleus inputs to the retrosplenial cortex are unperturbed in the hAPP-J20 mouse model of Alzheimer's disease #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2025.12.01.691675v1

N-Linked Glycosylation as a Driver of Tau Pathology and Neuronal Transmission #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2025.12.01.690311v1

Complex Emotion Recognition in Neurological and Neurodevelopmental Conditions #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.64898/2025.11.26.25341046v1

Disease-Associated HLA Alleles and Haplotypes in Multiple Sclerosis: Insights from an Albanian Case-Control Study #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.64898/2025.12.01.25341397v1

A Comprehensive Review of Casein Kinase 2 in Drosophila Circadian Timing and Its Biomedical Relevance #NeuroDegeneration 🧪🧠
https://arxiv.org/abs/2512.03191

The Protein Disulfide Isomerase P4HB/PDIA1 Modulates PrPC Levels and Prion Replication #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/10.64898/2025.12.01.691611v1

Dual-targeting snRNA gene therapy rescues STMN2 and UNC13A splicing in TDP-43 proteinopathies #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/10.64898/2025.12.01.691001v1

Anterior thalamic nucleus inputs to the retrosplenial cortex are unperturbed in the hAPP-J20 mouse model of Alzheimer's disease #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/10.64898/2025.12.01.691675v1

High molecular weight insoluble parkin in the substantia nigra of patients with idiopathic Parkinson’s disease #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8098616/latest

Diffusion tensor imaging and histopathological differences in dogs with and without cognitive dysfunction #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7776377/latest

Between Hope and Acceptance: A Case Report of Als and Realities of Palliative Care in Indonesia #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7783546/latest

Electroencephalographic slowing during REM sleep is a marker of cholinergic dysfunction in Lewy body disorders #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8131680/latest

Structural and functional brain abnormality patterns in patients with Parkinson’s disease: clinical correlations and implications #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8067456/latest