A/Prof Amy Cain

@livingseawalls.bsky.social is a finalist in the NSW DCCEEW Eureka Prize for Environmental Research.

Learn more: youtu.be/9yrRzgyZqoI

#EurekaPrizes @sims-australia.bsky.social @melaniejbishop.bsky.social @cariocamayer.bsky.social @marialvozzo.bsky.social

The Fission Chips Team from Macquarie University is a finalist in the @ansto.bsky.social Eureka Prize for Innovative Use of Technology.

Learn more: youtu.be/6yf27LdQkhw

#EurekaPrizes

Ian Paulsen has transformed #syntheticbiology from a niche science in Australia to a national strength. Under his leadership, our Centre has spun out ten startup companies that have raised more than $200 million in venture capital.

Join us in congratulating Ian on this fantastic achievement! 🎊

Water everywhere 😜 - with Mario @feldmanlab.bsky.social & Amy @flamycain.bsky.social at Acinetobacter conference in Niagara Falls

Fantastic conference! Fab company! Impressive waterfall :)

A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen - Nature Genetics A genome-wide screen using human gut epithelial organoids combined with transposon-directed insertion sequencing identifies over 100 Shigella flexneri genes required for epithelial colonization.

Very excited about our latest combining advanced cell culture, transposon-insertion sequencing, and statistical modeling to map Shigella virulence determinants in organoid models. Great collaboration w/ @mldm.bsky.social @sellinlab.bsky.social in @natgenet.nature.com

www.nature.com/articles/s41...

Cannabis extract shows promise as treatment for fungal infections

I'm excited to present our latest study in @plos.org NTDS, collaborating with @sydney.edu.au and UNSW that uncovers the potent antifungal activity of phytocannabinoids against life-threatening Cryptococcus and tinea/athletes foot fungi:

lighthouse.mq.edu.au/article/may-...

Reach out for more info!

Characterisation of Ornithobacterium hominis colonisation dynamics and interaction with the nasopharyngeal microbiome in a South African birth cohort. Ornithobacterium hominis is a recently described Gram-negative bacterium that colonises the human nasopharynx and may be associated with poor upper respiratory tract health. Here, we describe the isol...

Very pleased to share this preprint!

"Characterisation of Ornithobacterium hominis colonisation dynamics and interaction with the nasopharyngeal microbiome in a South African birth cohort"

🧵

www.biorxiv.org/content/10.1...

Congratulations to Associate Professor Amy Cain @flamycain.bsky.social of our #MacquarieUniversity node on being awarded The Australian Academy of Science (#AAS) 2025 #GottschalkMedal — in recognition of her pioneering work in the fight against #antibioticresistance 🦠💊

Group Leader (Microbes and Food Safety) at Quadram Institute Bioscience Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...

Anyone interested in joining us @quadraminstitute.bsky.social as part of @norwichmicro.bsky.social we’re recruiting for group leaders!

www.jobs.ac.uk/job/DMF274/g...

Centre startups secure AEA grants - ARC Centre of Excellence in Synthetic Biology Four startups from the Centre have successfully secured Australia’s Economic Accelerator (AEA) Ignite Grants, providing a shot in the arm for the local synthetic biology ecosystem.NewEra Bio, Levur, S...

🎉 Congratulations to Centre startups Levur, Newera Bio, Swan Genomics and Wild Yeast Zoo on securing Australia's Economic Accelerator (AEA) Ignite Grants!

Read the full story 👇 bit.ly/3DM9BY2

🦠 Job Opportunity in Microbiology! 🦠

UNSW Sydney is hiring a Lecturer/Senior Lecturer (Education Focused) in Microbiology! 🎓

📅 Apply by: March 31st, 2025: url.au.m.mimecastprotect.com/s/F9dHCRONg6...

Please share with your networks or anyone interested!

Editor-in-Chief, The Lancet Regional Health - Africa Do you enjoy using science to drive change in the world? Would you like to develop and launch an online-only gold open access journal for The Lancet. About our Team The Lancet Regional Health -Africa ...

✨ Exciting new Lancet role ✨

This autumn, our Group is launching an OA journal dedicated to the unique health challenges on the African continent: The Lancet Regional Health—Africa 🌍

To lead this important endeavour, we are searching for an Editor-in-Chief. Find out more & apply ⤵️
bit.ly/3Xp919w

📣Students and ECRs of Microbiology in NSW!

The ASM travel award application deadlines are coming up on the 28th Feb and 17th March 2025.

Make sure you apply below:

Student Nancy Millis: asm-nswact.org.au/wp-content/u...

ECR BD Award: asm-nswact.org.au/wp-content/u...

Major Funding Boost for Combating Fungal Infections - ARC Centre of Excellence in Synthetic Biology An international research collaboration, including Macquarie University's Associate Professor Amy Cain, has received €1 million to tackle the growing global crisis of antifungal resistance. This escal...

🌍 A global research collaboration, including Macquarie University’s Associate Professor Amy Cain, has been awarded €1 million to combat the growing crisis of antifungal resistance.

Congratulations! 👏👏👏

bit.ly/4jkB6YO

Super excited to announce that we’ve successful in an important new NHMRC/JPIAMR grant developing new metal-containing antifungals. Looking forward to working with some fantastic collaborators across Europe!

url.au.m.mimecastprotect.com/s/Ur_tCWLVn6...

Huge congratulations to my talented PhD student Geraldine Sullivan and amazing MRes student Natasha Delgado who graduated from Macquarie University yesterday - both with VC awards!

Feeling proud and grateful to work with such fantastic students - looking forward to watching your careers grow!

A method to correct for local alterations in DNA copy number that bias functional genomics assays applied to antibiotic-treated bacteria | mSystems Altered gene dosage due to changes in DNA replication has been observed under a variety of stresses with a variety of experimental techniques. However, the implications of changes in gene dosage for s...

Are you applying RNA-seq or TraDIS/Tn-seq to antibiotic-treated bacteria? Our paper from earlier this year with @flamycain.bsky.social shows that antibiotic interference with chromosome replication can confound functional genomics analyses! Thread 1/n journals.asm.org/doi/full/10....

And most of the credit should go to Geri Sullivan for all the hard work, and her PhD supervisor (and excellent collaborator!) @flamycain.bsky.social

Improved prediction of bacterial CRISPRi guide efficiency from depletion screens through mixed-effec... CRISPR interference (CRISPRi) is the leading technique to silence gene expression in bacteria; however, design rules remain poorly defined. We develop a best-in-class prediction algorithm for guide si...

Very pleased to finally see this out in Genome Biology: we used mixed-effect machine learning to predict CRISPRi guide efficiency, learning more about the system along the way. Work from very talented former PhD student Yanying Yu, now postdoc at Broad Institute. link.springer.com/article/10.1...

Check out the latest Microbiology Primer on using TraDIS to link genotype to phenotype www.microbiologyresearch.org/content/micr...

Cool new paper from Ian Paulsen and co - Systematic analyses identify modes of action of ten clinically relevant biocides and antibiotic antagonism in Acinetobacter baumannii www.nature.com/articles/s41...