Florian Privé

LEAVING ACADEMIA

Although I did not manage to secure the funding needed to establish my own research group, I am grateful for what I’ve learned in academia.

*I am now beginning a new chapter*, joining a very early startup in France working on detecting cancer from DNA circulating in the blood.

But you shouldn’t use only 2 PCs to compute the distance 😉

I probably won't have time to make a video out of this.

But the materials are available online, and should be pretty self-explanatory.

Hope this is useful to some people.

privefl.github.io/statgen-cour...

Next week, I'm teaching a **Statistical Human Genetics course using R**; would be of interest if I try to record it to make it available as a Youtube video?

FIMM-EMBL Group Leaders in Molecular Medicine FIMM-EMBL Group Leaders in Molecular Medicine

We have 2-3 group leader positions opening @fimm-uh.bsky.social !!

We are looking for outstanding candidates in human genetics and precision medicine.

This time we have a focus on population health data science. E.g. AI for EHR/health data       

Generous starting package 💰

shorturl.at/FAk6n

Did you make it? 😁

We are looking for a post-doc/research fellow working on non-bullshit, reality-centered AI.

Meaning: unique nationwide EHR and -omics with the possibility to recontact people and prospectively test multimodal AI approaches.

jobs.helsinki.fi/job/Helsinki...

@FIMM_UH @FinnGen_FI

This is VERY big genetics & health news, Regeneron (Pharmaceutical company with v strong genetics in medicine arm) is going to buy 23andme. investor.regeneron.com/news-release...

I am recruiting a quantitative/computational postdoc to my group at UCLA. This is a great opportunity to work on foundational theory, methods, and software in statistical genetics. Link to apply: recruit.apo.ucla.edu/JPF10275. Please repost!

Yes, but the sample sizes are quite small there.

Thanks!

I actually use a few people from the 1000G as well, to get a few more people from Finland, Japan, and South America.

In the future I would like to also add the Papuan from the SGDP.

✅ In this paper, I used the UK Biobank to define 18 reference worldwide populations, and provided a method to easily infer ancestry proportions of individuals from your study more accurately.

Please have it a try!

Paper: doi.org/10.1093/bioi...
Tutorial: privefl.github.io/bigsnpr/arti...

👀 I still see many papers using the 1000G data to infer ancestry proportions of individuals in their respective studies.

❌ But I argue that the 1000G is not doing a very good job at covering well the worldwide populations.

Not sure. I think someone provided some VCF -> bed -> BGEN conversion.
Not sure what is this DRAGEN.

Did they update the BGEN files they provide?
Initially they were missing 30% of variants.

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⏳ Apply by April 19 — limited spots available!
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Potential Main or Co-Supervisors include:

Naomi Wray (Oxford), Peter Visscher (Oxford), Erin Gabriel (KU), Preben B Mortensen (AU), @eagerbo.bsky.social
(AU), @privefl.bsky.social (AU), Thomas Gerds (KU), Julie Dreier (AU), and others.

Join us for the ISPG Members' Meetup on March 26th!

Dr. Oliver Pain will present his groundbreaking research on polygenic scores and the innovative GenoPred pipeline.

Don't miss out: us06web.zoom.us/meeting/regi...

#ISPG #Genetics #PolygenicScores #Bioinformatics

I'll be there!
This is a very affordable conference on Statistical Genetics methodologies 🤩

Postdocs in Epidemiology or Statistical Genetics at The Pioneer Centre for SMARTbiomed - Vacancy at Aarhus University Vacancy at Department of Public Health - NCRR - National Centre for Register-based Research, Aarhus University

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You’ve been murdered who do you want on the case?

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Looking for a PhD position in statistical methods development for causality? Then we might be looking for you! jobportal.ku.dk/alle-opslag/...

Abstract submissions for the European Mathematical Genetics Meeting are open! emgm2025.sciencesconf.org Deadline February 2nd, looking forward to seeing your proposals. Meeting is in Brest, France, 8-9 April

Genetic PCs rarely provide large % of variation, but I don’t think it means they’re not useful.

Try to look at the loadings if possible.

Are there any peaks?
Cf. privefl.github.io/bigsnpr/arti...

I meant the looking of the PC scores.
Did you look at the PC loadings?

The PCA is indeed a bit odd; are you sure you’re not capturing LD instead of population structure?

My standing « desk », by the fireplace 😊

Sinner