Indra Roux

A brand-new Gordon Conference on Microbiomes!🦠 The opening session (Jan 2026) dives into microbiome editing - how fundamental research and new technologies can advance human health and environmental sustainability. Super looking forward!🧪 #microsky #microbiomesky #grc
www.grc.org/microbiome-e...

Deep-learning-based virtual screening of antibacterial compounds - Nature Biotechnology Antibacterial compounds are discovered by combining phenotypic screening with deep learning.

Deep-learning-based virtual screening of antibacterial compounds go.nature.com/47oIdKy

Pleased to have contributed to this Genentech-led research with NVIDIA featured today in @natbiotech.nature.com presenting GNEprop, an AI model that identifies novel antimicrobial compounds beyond known chemical space. Mila’s contributions were led by @yoshuabengio.bsky.social & Michał Koziarski.

Banner with "Meet the EngBio Early Career Researchers" - Nikos Nikolopoulos.

In a new series, we're introducing you to some of our #EngBio Early Career Researchers.

Meet Nikos Nikolopoulos, Postdoctoral Research Fellow, Department of Medicine Molecular Immunity Unit (MIU) at @mrclmb.bsky.social. View Nikos' profile: www.engbio.cam.ac.uk/nikos-nikolo...

#EngBioECRs

From #drug cabinet → gut #microbiome: screening 312 therapeutic compounds, we mapped 4.6 million microbial protein-level responses to reveal how our drugs don’t just target us, they hit our gut microbes too.

rdcu.be/eMmcT

MITE training session registration form Registration form for mailing list

Working on tailoring enzymes and want to learn more about the MITE database? We are organizing a hands-on training session on how use the DB and create new entries: October 30th and November 4th 10-11 am Amsterdam time. Sign up here: forms.gle/KHPqe9XV1RRg... See you there! #secmet #natprod

Microbiome Metabolism and Metabolites: Discovery and Function in Health and Disease | Keystone Symposia Join us at the Keystone Symposia on Microbiome Metabolism and Metabolites: Discovery and Function in Health and Disease, January 2026, in Banff, with field leaders!

Explore emerging research with field leaders @keystonesymposia.bsky.social #Microbiome Metabolism & #Metabolites, this January in Banff! @molsystbiol.org scientific editor Poonam Bheda will attend.

Early registration deadline is Nov 20th => keysym.us/KSMicroMetab26 #KSMicroMetab26

Systematic metaproteomics mapping reveals functional and ecological landscapes of Ex vivo human gut microbiota responses to therapeutic drugs Nature Communications - Here, the authors systematically map metaproteomic responses of ex vivo human gut microbiota to common therapeutics, identifying several drug classes inducing strong...

Interested in #drugs, #microbiome and #antibiotic resistance, then check out our paper on the effects of over 300 drugs on the gut microbiome. Exciting results as well on the role of antibiotic resistance defining how microbiomes respond to drugs.
@quadraminstitute.bsky.social

rdcu.be/eMmcT

Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation Moretti et al. show a gut bacterial consortium (L. mucosae and L. ruminis) producing serotonin, increasing fecal serotonin and enteric neuron density and normalizing intestinal motility in mice. Reduc...

Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation
www.cell.com/cell-reports...
Serotonin produced by gut bacteria provides hope for a novel IBS treatment
medicalxpress.com/news/2025-10...

Please join us at Café Synthetique on 3 Nov with talks:

🍶Gut feelings: engineering smart probiotics that can sense disease @driglar.bsky.social
🧫Seeing Nanomaterials in Action, from Cellular Senescence to NanoDynamic Imaging - Andrew Baker @phar.cam.ac.uk

🎟️👉 www.tickettailor.com/events/engin...

A week to go... #EngBio ECRs Meetup returns on 20 Oct. Join us to hear great talks from Konstantina Beritza and
Caroline Faessler 🌱 Don't miss it!
@camplantsci.bsky.social

Sign up here👉 www.tickettailor.com/events/engin...

#plantsciences #marinemicroalga #Nicotianabenthamiana

Photo of Grand Prismatic Springs, Yellowstone (home of thermophilic bacteria) Photo by Mike Goad https://flic.kr/p/Gm8fZc

Pandas, snow leopards...and bacteria. A newly formed team of scientists is setting out to conserve the world's diversity of microbes. Here's my story: nyti.ms/47vEfRC

illumina mvif webinar

SAVE THE DATE: 27 October, 2025
and join speakers from both illumina and #MVIF!

Registration for the webinar is free: emea.illumina.com/events/webin...

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We're excited to help launch the inaugural Gordon Research Conference on #microbiome #GenomeEditing, coming up in January in Pomona, CA! Learn more and register here: https://ow.ly/63z150X9XkG

μGrowthDB: querying, visualizing, and sharing microbial growth curve data www.biorxiv.org/content/10.1... #jcampubs

If you feel like contributing your microbial growth data, take a look at μGrowthDB

mgrowthdb.gbiomed.kuleuven.be

You can also read the preprint: www.biorxiv.org/content/10.1...

🧬🖥️🧪🦠🧫

Predicting functions of uncharacterized gene products from microbial communities - Nature Biotechnology FUGAsseM predicts protein function in microbiomes using coexpression patterns from metatranscriptomes and diverse community-wide data.

Predicting functions of uncharacterized gene products from microbial communities www.nature.com/articles/s41... #jcampubs

Amazing resource—hope it gets used broadly and we see TnSeq datasets become more common for Bacteroidales.

#microsky 😮

This is one of the most common types of bacteria in the human gut - and @typaslab.bsky.social lab @embl.org is doing the hard yards to being able to understand this critical bacteria in far far more detail. Rock on!

Great paper, and also nice evidence that you can create large+diverse RB-TnSeq libraries in liquid selection, without the need to scrape tons of plates for your library.

We systematically compared essential genes, protein domains & non-coding elements, uncovering toxic modalities & functional redundancy as key aspects of species-specific essentiality.

Excited to share our preprint led by Carlos Voogdt et al

We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...

New Preprint from Voogdt et al 👇

Establishes efficient genome-wide transposon mutagenesis & barcode mutant libraries for three Bacteroidales gut bacteria, identifying shared & species-specific essential genes, non-coding elements, & toxin pathways, advancing gut microbiome functional genomics

Important (and meticulous) genetic groundwork by the @typaslab.bsky.social and Carlos Voogt on gut microbiome Bacteroides species! Enormous value for the functional microbiome research community

Targeted protein evolution in the gut microbiome by diversity-generating retroelements Diversity-generating retroelements (DGRs) accelerate evolution by rapidly diversifying variable proteins. The human gastrointestinal microbiota harbors the greatest density of DGRs known in nature, su...

Targeted protein evolution in the gut microbiome by diversity-generating retroelements | Science www.science.org/doi/10.1126/...

How exercise promotes the immune system vs cancer, working through a gut bacteria metabolite
www.cell.com/cell/abstrac...

Join us at Café Synthetique on Mon 6 Oct! with talks on:

🌱 Fuelling the Future with #Cyanobacteria — Angelo Joshua Victoria @gelomerase.bsky.social

💡 Green #Biomanufacturing through Light-Driven Systems — Lin Su (QMUL)

🎟️ Register at www.tickettailor.com/events/engin...

Don’t miss it!

#EngBio ECRs Meetup returns on 20 Oct. Join us to hear great talks from Konstantina Beritza and
Caroline Faessler 🌱
@camplantsci.bsky.social

Sign up here👉 tickettailor.com/events/engin...

#plantsciences #marinemicroalga #Nicotianabenthamiana

Cover of the 2025 EAT–Lancet report, featuring an image of a person scooping up green vegetables in their hands from a large plate. The report quote: “The targets of the EAT–Lancet Commission for healthy people on a healthy planet with just food systems can only be met through concerted global action and unprecedented levels of transformative change.”

The world produces enough food, yet billions lack access to healthy & sustainable diets. A new EAT–Lancet report presents a science-based approach to improve health, safeguard our environment & provide for a projected 9.6 billion people by 2050.

🔗 bit.ly/3W7rxlP