ꙮ Pavel Janoš ꙮ's Avatar

ꙮ Pavel Janoš ꙮ

@pjanos.bsky.social

Researcher at CNR-IOM c/o SISSA, Trieste, Italy. MD, protein/RNA, drug design. 'I didn’t ask to be a multicellular organism.' https://magistratogroup.wordpress.com/

312 Followers  |  551 Following  |  2 Posts  |  Joined: 14.11.2024  |  1.754

Latest posts by pjanos.bsky.social on Bluesky

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📢 Save the Date!

We are thrilled to announce that the Congress of our Division will be held in Palermo.

🗓️ September 16-18, 2026.
See you next year in Sicily!

🛍️As always, scholarships will be available for young researchers.

The website will be available soon!
#DCSB2026

16.10.2025 18:58 — 👍 1    🔁 1    💬 0    📌 0
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RNA G-quadruplexes emerge from a compacted coil-like ensemble via multiple pathways Abstract. RNA G-quadruplexes (rG4s) are emerging as vital structural elements involved in processes like gene regulation, translation, and genome stability

Just published: RNA G-quadruplex folding mechanism via all-atom simulations in collaboration with my former PhD lab. Many thanks to Petr, Jiří, Vojtěch, and the reviewers, who encouraged us to pursue folding the full human telomeric G4.
academic.oup.com/nar/article-...

10.09.2025 07:29 — 👍 4    🔁 1    💬 0    📌 0
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Evolutionary Constraints Guide AlphaFold2 in Predicting Alternative Conformations and Inform Rational Mutation Design Investigating structural variability is essential for understanding protein biological functions. Although AlphaFold2 accurately predicts static structures, it fails to capture the full spectrum of f...

Our study is now published on JCIM🎉

We expanded and refined the preprint thanks to the insightful feedback from reviewers!

paper: pubs.acs.org/doi/10.1021/...
code: github.com/RitAreaScien...

04.09.2025 07:49 — 👍 9    🔁 4    💬 0    📌 1
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Almost at the end of the exciting @cecamevents.bsky.social conference 'RNA Modelling across scales' at SISSA, Trieste, Italy! 🎉 Fantastic speakers and great science. Organized with @bussigio.bsky.social @marcodevivo.bsky.social #RNA

21.05.2025 19:22 — 👍 19    🔁 8    💬 0    📌 3

Our integrative approach using #MD and #cryoEM data to construct structural ensembles of #RNA just published on @natcomms.bsky.social doi.org/10.1038/s414... Lead by Elisa Posani, with @magistratolab.bsky.social @bonomimax.bsky.social @pjanos.bsky.social @navtejtoor.bsky.social and Daniel Haack 🎉

16.05.2025 09:16 — 👍 26    🔁 8    💬 0    📌 0
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We are sill accepting applications for poster presentations at the CECAM conference 'RNA Modelling Across Scales". Join us in the beautiful Trieste ☀️🏖️🏰! Apply now: www.cecam.org/workshop-det... Co-organized with @bussigio.bsky.social @marcodevivo.bsky.social

27.03.2025 19:04 — 👍 10    🔁 5    💬 0    📌 0
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333 neviditelných obleků pro ukrajinské speciály - Dárek pro Putina Nebýt viděn je základ každého úspěšného boje. Teď v době, kdy na frontě vládnou drony vybavené termokamerami, je to čím dál těžší. Ale není to nemožné. Chceme na frontu poslat 333 speciálních nevidite...

Tohle je moc pěkná věc. 😍 Oblek, který vás zneviditelní před dronem vybaveným termokamerou. Zdokonalený a vyrobený v České republice. Chceme jich koupit 333 pro ukrajinské speciály. Na půlku vybíráme peníze a druhou zaplatí partneři z ColtCZ.

www.zbraneproukrajinu.cz/kampane/nevi...

11.03.2025 14:23 — 👍 98    🔁 27    💬 1    📌 1
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All-Atom Simulations Elucidate the Molecular Mechanism Underlying RNA–Membrane Interactions RNA–membrane interactions are starting to emerge as an important organizing force in both natural and synthetic biological systems. Notably, RNA molecules were recently discovered to be present on the...

Interested in understanding the molecular details of RNA–membrane association? Read our new paper just published in Nano Letters @acs.org. Excellent work done by sdimarco.bsky.social with Jana Aupic and @bussigio.bsky.social pubs.acs.org/doi/full/10....
#RNA #MembraneBiology #compchem #compbiol

09.03.2025 11:39 — 👍 9    🔁 3    💬 0    📌 0
Post image 28.02.2025 19:32 — 👍 1038    🔁 228    💬 12    📌 2
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News - EuChemS WINNER ANNOUNCEMENT! “EuChemS ChemBioLife Young Investigator Award” 2024-2025 edition   We are proud to announce the winner of the EuChemS ChemBioLife Young Investigator Award  of the EuChemS Division...

Very proud to announce that a member of our group, Dr. Jana Aupič, has been awarded the prestigious "EuChemS ChemBioLife Young Investigator" prize! 🏅 This honors her hard work and exceptional contribution to chemical biology. Congratulations, Jana! 🌟✨ .
www.euchems.eu/divisions/ch...

04.02.2025 16:03 — 👍 10    🔁 5    💬 0    📌 0
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Today, we honor the defenders of Donetsk Airport—our legendary Cyborgs. Ten years ago, under relentless shelling for 242 days, they stood their ground and showed the world the unbreakable strength of Ukraine.

20.01.2025 10:10 — 👍 151    🔁 27    💬 3    📌 2
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Assessing the Mechanism of Rac1b: An All-Atom Simulation Study of the Alternative Spliced Variant of Rac1 Small Rho GTPase The Rho GTPase family plays a key role in cell migration, cytoskeletal dynamics, and intracellular signaling. Rac1 and its splice variant Rac1b, characterized by the insertion of an Extraloop, are fre...

Just published in Journal of Chemical Information and Modeling our new study on the Mechanism of Rac1b: the Alternative Spliced Variant of Rac1 Small Rho GTPase. Great work by A. Parise and S. Cresca!
pubs.acs.org/doi/10.1021/...

09.12.2024 15:33 — 👍 15    🔁 6    💬 0    📌 0

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27.11.2024 07:11 — 👍 1    🔁 0    💬 0    📌 0
Prague's Kafka International Named Most Alienating Airport
YouTube video by The Onion Prague's Kafka International Named Most Alienating Airport

Prague's Kafka International Named Most Alienating Airport

26.11.2024 18:00 — 👍 1942    🔁 196    💬 44    📌 31

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23.11.2024 10:52 — 👍 0    🔁 0    💬 0    📌 0

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