EvolutionaryScale

Biohub launches initiative combining frontier AI & frontier biology The large-scale scientific effort combines frontier AI with frontier biology to accelerate discovery and solve disease.

EvolutionaryScale will be joining forces with Biohub to create the first large-scale scientific initiative combining frontier AI & frontier biology. Together, we're building world-class compute, AI research & state-of-the-art technologies to cure or prevent disease. bit.ly/4nOUGO4

06.11.2025 18:04 — 👍 3    🔁 1    💬 0    📌 0

We're sponsoring the use of ESM3 and EMSC to help researchers engineer improved PETase enzymes in the @AlignBio 2025 Protein Engineering Tournament.

Get started using ESMC to predict protein function and ESM3 to generate new enzymes here: github.com/evolutionary...

08.07.2025 18:01 — 👍 9    🔁 3    💬 0    📌 1

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🚀 Announcing the 2025 Protein Engineering Tournament.

This year’s challenge: design PETase enzymes, which degrade the type of plastic in bottles. Can AI-guided protein design help solve the climate crisis? Let’s find out! ⬇️

#AIforBiology #ClimateTech #ProteinEngineering #OpenScience

08.07.2025 16:26 — 👍 23    🔁 20    💬 1    📌 4

Scaling curves for ESM C protein language models. Model performance improves predictably with scale.

Information about protein structure improves predictably with increasing training compute, demonstrating linear scaling across multiple orders of magnitude.

We overtrained ESM C 300M and 600M beyond the compute-optimal point predicted by the scaling curves.

04.12.2024 17:45 — 👍 6    🔁 0    💬 0    📌 0

Model Scale vs. Performance curves for ESM C models, with comparisons to ESM2 and other protein LMs. ESMC performs better than existing state of the art for the same model parameter scale.

Introducing ESM Cambrian, a new family of protein language models, focused on creating representations of the underlying biology of proteins.

04.12.2024 17:45 — 👍 50    🔁 16    💬 1    📌 2