Jan Stundl

🔔 Please share 🔔 I have two open developmental biology/genetics/evo-devo PhD project vacancies for October 2026 start.

1 = 🐚 🐌 🔬(embryos!!)
⏱️📆 DEADLINE 15th DEC 📆⏱️ (competition)
sleightlab.com/vacancies/

2 = 🦪 🐌 🧬
⏱️📆 DEADLINE 14th JAN 📆⏱️(fully funded)
sleightlab.com/phd-vacancy-2/

“Fish” can refer to a single individual, or multiple individuals from the same species.

“Fishes” refers to multiple species.

🐠 Fish
🐠🐠🐠 Fish
🐠🐟🐡 Fishes

Deadline to register for Get Into Grad School Webinar approaching! Share with interested #undergraduates and #postbacs Registration Deadline: Thursday, September 18. bit.ly/3HFJ9BG

Congratulations Vish 👏 and Vicky 🎉👏

Oh man, I am so excited and happy to have been given this huge opportunity by the @erc.europa.eu It is by no exaggeration - a dream come true.
An insufficient thank you thread (1/4)

Congratulations Anna 👏👏👏

EARLY BIRD PRICING ENDS TODAY! #Science takes flight at the XII Avian Model Systems Meeting, and you can save by registering early! #AvianModels25

🐥 Secure your early bird rate today: bit.ly/3ZBw2qS

Looking for a #postdoc opportunity? Funded positions available @cuanschutz.bsky.social to advance our #zebrafish transgenesis tools - and to look into developmental origins of congenital disease!
#devbio

My Department (Biology) at @dartmouthartsci.bsky.social is hiring this year! We have an opening for a Tenure Track Cell and/or Molecular biologist (broadly defined).

Please share with your trainees/labmates/friends and reach out if you have questions.

apply.interfolio.com/171625

EMBL is an amazing place to start a lab and bring new direction to your research program (ask me how I know) - come join us in Heidelberg !

Endless thanks to the incredible collaborators who brought this project to life—you’re the magic behind it all @dayyapparaja.bsky.social @urrutiahugo.bsky.social @jakeleyhr.bsky.social J.Stundlova, T. Solovieva, T. Haitina, S. Sanchez @fishevo.bsky.social M. Martik and my great boss Marianne Bronner

Together, our findings raise the intriguing possibility that integration of neural crest into the endostyle developmental program may reflect an important evolutionary step in thyroid development and particularly in the formation of a bilobed gland.

Interestingly, our results align with findings in chick embryos, where neural crest ablation leads to hypoplasia or aplasia of pharyngeal-derived endocrine glands (e.g. thyroid gland-Maeda et al., 2016).

We then asked: What happens when neural crest development is disrupted? Using CRISPR/Cas9 to mutate several genes from the neural crest gene regulatory network, we generated crispants with single-lobed endostyles that morphologically resemble those of non-vertebrate chordates.

Since the neural crest — a cell type unique to vertebrates — plays a key role in thyroid development, we asked: does it also help build the lamprey endostyle? Our lineage tracing revealed that it does, contributing even to cells destined to become the thyroid.

While non-vertebrate chordates have simple, groove-like endostyles, lampreys boast a bilobed version packed with specialized cells — including the precursors of adult thyroid follicles.

In this #evodevo project, we explored how the #neuralcrest influences the development of the endostyle — the evolutionary precursor of the thyroid gland. The endostyle, an endoderm-derived organ unique to chordates and key to filter feeding, is found in vertebrates only in #lamprey

Acquisition of neural crest promoted thyroid evolution from chordate endostyle Integration of neural crest cells into the endostyle developmental program promoted its evolution into the thyroid gland.

Excited to announce that our new paper is now published in Science Advances 🚀🧠 ‘Acquisition of neural crest promoted thyroid evolution from chordate endostyle’ — check it out here: www.science.org/doi/10.1126/...

Interestingly, our results align with findings in chick embryos, where neural crest ablation leads to hypoplasia or aplasia of pharyngeal-derived endocrine glands (e.g. thyroid gland - Maeda et al.,2016)

We then asked: What happens when neural crest development is disrupted? Using CRISPR/Cas9 to mutate several genes from the neural crest gene regulatory network, we generated crispants with single-lobed endostyles that morphologically resemble those of non-vertebrate chordates.

Since the neural crest— a cell type unique to vertebrates — plays a key role in thyroid development, we asked: does it also help build the lamprey endostyle? Our lineage tracing revealed that it does, contributing even to cells destined to become the thyroid.

While non-vertebrate chordates have simple, groove-like endostyles, lampreys boast a bilobed version packed with specialized cells — including the precursors of adult thyroid follicles.

In this project, we explored how the #neuralcrest influences the development of the endostyle — the evolutionary precursor of the thyroid gland. The endostyle, an endoderm-derived organ unique to chordates and key to filter feeding, is found in vertebrates only in #lamprey

Thank you so much, Kev! 🤗

Universitetslektor i människans palaeo-och populationsgenomik - Uppsala universitet Universitetslektor i människans palaeo-och populationsgenomik, Disciplinary Domain of Science and Technology, Faculty of Biology, Department of Organismal Biology, Uppsala universitet

#Job alert: associate professor (universitetslektor) at the program in Human #Paleogenomics and #Population #Genomics. Please see the ad for more information. Application deadline: Sept 1st. #vacancy @haam-community.bsky.social @cschlebu.bsky.social

www.uu.se/om-uu/jobba-...

Thanks, Rigolin 🙏

Great news! Congratulations guys 🍾🥳👏

Flores-Flores in 2025 Class of Pew Latin American Fellows Pursuing Scientific Advances Pediatrics Postdoctoral Fellow Marycruz Flores-Flores, PhD, is one of 10 in the 2025 class of the Pew Latin American Fellows Program in the Biomedical Sciences announced today by The Pew Charitable Trusts.

🎉 Big news! 10 postdoc fellows from 5 Latin American countries have joined the 2025 class of #PewLatinAmericanFellows, and we’re proud to share that one is our own @mary-flores.bsky.social! Learn more: bit.ly/45rgN5L @cumedicalschool.bsky.social @cuanschutz.bsky.social @chrmosimann.bsky.social

Thank you, Marco!

Thanks a lot, Christian 🙏