Sheila Macrine, PhD

How are the self, space, and time related? A new study on #depersonalization found feeling disconnected from your body-linked to time slowing down, & feeling detached from the world-linked to time speeding up. @Annaciaunica tinyurl.com/bdh4thdb #Neuroscience #TimePerception #Consciousness

A brain-wide map of decision-making! 🧠 Study reveals how sensory inputs, choices & motor actions are encoded across 279 brain regions. Dataset publicly available
#Neuroscience #BrainMapping #DecisionMaking #OpenScience #BigData #Neuropixels t.co/54Lc3CmYgV

What do proteins, animal forms & languages have in common? #Evolution! Unified framework detects evolutionary leaps #branching across #molecular, #morphological, and #cultural scales onlinelibrary.wiley.com/doi/epdf/10....
#Genomics #Adaptation
#ComputationalBiology #Biology

New research calls an Alzheimer's protein "chameleon-like." 🦎 It shape-shifts to form toxic plaques, but this same flexibility also allows the plaques to break apart. onlinelibrary.wiley.com/doi/epdf/10.10…
#Alzheimers #amyloid #research #neuroscience #proteinfolding #dementia

Beetle grows ‘termite’ on back to steal food Puppet helps insect trick real termites into feeding it

Nature's #biomimicry at its finest! rove beetle that grows a hyper-realistic "termite puppet" on its back to steal food 🐜 scim.ag/40kQtbI h/t @justinechterna9
#mimicry #evolution #entomology #newspecies #insects #natureiswild

Evolution is coupled with branching across many granularities of life | Proceedings of the Royal Society B: Biological Sciences Across many scales of life, the rate of evolutionary change is often accelerated at the time when one lineage splits into two. The emergence of novel protein function can be facilitated by gene duplication (neofunctionalization); rapid morphological ...

royalsocietypublishing.org/doi/10.1098/...

Evolution is coupled with branching across many granularities of life | Proceedings of the Royal Society B: Biological Sciences Across many scales of life, the rate of evolutionary change is often accelerated at the time when one lineage splits into two. The emergence of novel protein function can be facilitated by gene duplication (neofunctionalization); rapid morphological ...

royalsocietypublishing.org/doi/10.1098/...

YouTube video by Mind-Body Solution Terrence Deacon & Michael Levin: What is Life? Complexity, Cognition & the Origin of Purpose

What is Life?" @drmichaellevin.bsky.social
& #TerrenceDeacon unite thermodynamics and cognition across all scales, bridging #EvoDev, #cogsci & #philosophy. Inspired by @danieldennett's legacy. youtu.be/HuWbHwPZd60?fe… #Evolution
#Biology #Philosophy #Consciousness #Complexity

YouTube video by Mind-Body Solution Karl Friston & Mark Solms: Is it Possible to Engineer Artificial Consciousness?

Can We Engineer Artificial Consciousness?" Professors Karl Friston & Mark Solms, pioneers in #neuroscience, #psychology, and theoretical #biology, dive into the frontiers of #consciousness @KarlFristonNews @Mark_Solms youtu.be/Jtp426wQ-JI?...

Evolution is coupled with branching across many granularities of life | Proceedings of the Royal Society B: Biological Sciences Across many scales of life, the rate of evolutionary change is often accelerated at the time when one lineage splits into two. The emergence of novel protein function can be facilitated by gene duplic...

royalsocietypublishing.org/doi/10.1098/...

Evolution is coupled with branching across many granularities of life | Proceedings of the Royal Society B: Biological Sciences Across many scales of life, the rate of evolutionary change is often accelerated at the time when one lineage splits into two. The emergence of novel protein function can be facilitated by gene duplic...

royalsocietypublishing.org/doi/10.1098/...

Evolution is coupled with branching across many granularities of life | Proceedings of the Royal Society B: Biological Sciences Across many scales of life, the rate of evolutionary change is often accelerated at the time when one lineage splits into two. The emergence of novel protein function can be facilitated by gene duplic...

Sorry the one on top of it works. But here you go. royalsocietypublishing.org/doi/10.1098/...

Which link? Air there are a few.

The Sudden Surges That Forge Evolutionary Trees | Quanta Magazine An updated evolutionary model shows that living systems evolve in a split-and-hit-the-gas dynamic, where new lineages appear in sudden bursts rather than during a long marathon of gradual changes.

An updated evolutionary model shows that living systems evolve in a split-and-hit-the-gas dynamic, where new lineages appear in sudden bursts rather than during a long marathon of gradual changes. #Evolution #Biology #Adaptation www.quantamagazine.org/the-sudden-s...

An open-source AI platform to democratize protein design Since its release last year, the open-source platform BindCraft, developed at EPFL, has already disrupted the world of protein design.

Open-source AI platform is democratizing the design of custom proteins! 🧬 It "reverse-engineers" the process, to create specific protein binders for therapeutic research applications. share.google/zQLs8VH9S7jm...
#OpenSource #AI #ProteinDesign #Biotechnology #ScienceForAll

Why AI gets stuck in infinite loops — but conscious minds don’t Anil Seth suggests the difference is that living beings are rooted in time and entropy, a grounding that may be essential for consciousness.

Why does AI get stuck in infinite loops?
"Unlike computers, we are beings in time-embodied, embedded, and entimed in our worlds. We can never be caught in infinite loops because we never exist out of time." bigthink.com/neuropsych/a...

Cool interview with Karl Friston x.com/mlstreettalk...

Inner speech in motor cortex and implications for speech neuroprostheses Inner speech is robustly represented in the motor cortex and can be decoded in real time to restore communication to people with paralysis. Unintentional decoding of private inner speech can be preven...

New research shows a #BCI can decode a person's silent, inner speech into full sentences. Tapping into the brain's motor cortex, revolutionizing communication for those who cannot speak.
#Neuroscience #BrainComputerInterface #Neurotech #Accessibility
www.cell.com/cell/fulltex...

A beautiful loop: An active inference theory of consciousness Can active inference model consciousness? We offer three conditions implying that it can. The first condition is the simulation of a world model, whic…

Can active inference model consciousness? New paper proposes it can, via a "Beautiful Loop Theory." It rests on three key conditions that create a self-evidencing system. 🧠 @KarlFristonNews
#Consciousness #ActiveInference ##FEP
www.sciencedirect.com/science/arti...

Really intriguing talk coming up by @annaciaunica.bsky.social
on whether you need a body to be somebody, a self ?
FREE Online access Artificial General Intelligence (AGI25 ) Conference August 10-13 AGI sign up. agi-conf.org/2025/
Also a link to @AnnaCiaunica paper.
osf.io/preprints/psya…

Just reposted. Let me know. I only post open access. So thanks for the heads up. I think it is so important to share science without journal paywalls.

The breakthrough proof bringing mathematics closer to a grand unified theory The Langlands programme has inspired and befuddled mathematicians for more than 50 years. A major advance has now opened up new worlds for them to explore.

Breakthrough! After 50 years, a monumental proof in abstract mathematics is bringing us closer to a Grand Unified Theory! This quiet revolution is one of science's biggest stories. #Mathematics #ScienceNews #GrandUnifiedTheory #AbstractMath
www.nature.com/articles/d41...

Hepatitis C found in the brain lining of individuals with schizophrenia and bipolar disorder suggesting link between HCV infection and these psychiatric conditions. hopkinsmedicine.org/news/newsroom/… #HepatitisC #MentalHealth #Schizophrenia #BipolarDisorder

YouTube video by Giant's Shoulder Meet the Scientist Creating New Forms of Synthetic Life! Dr Michael Levin

Dive into the incredible world of Xenobots! 🐸 These living robots challenge our understanding of life, intelligence, consciousness. youtu.be/LTBZRVKUwyM?si… @drmichaellevin @Evan_mcgl
#Xenobots #Bioengineering #AI #Consciousness #Science

Exploring cognitive diversity. Timely and valuable reframing.

This tiny brain molecule could hold the key to learning, memory—and Alzheimer’s treatment A team of researchers has discovered that a protein called cypin plays a powerful role in helping brain cells connect and communicate, which is crucial for learning and memory. By uncovering how cypin...

Researchers discovered that a protein called cypin can help brain cells connect and communicate. This could be a game-changer for treating Alzheimer's, Parkinson's, traumatic brain injuries. #BrainHealth #Research #Science #Memory #TBI #Neurodegeneration share.google/QkMxGPt6DQbb...

Selection shapes diverse animal minds | Philosophical Transactions of the Royal Society B: Biological Sciences This special issue explores the evolution of cognitive diversity across the animal kingdom, challenging the value of approaches that have a basis in human psychology in favour of a perspective that em...

How are animal minds shaped by evolution? 🧠 Explore cognitive diversity across the animal kingdom, moving beyond human-centric views. Reframes cognition as a set of diverse solutions to environmental challenges. #AnimalCognition #Evolution doi.org/10.1098/rstb...

Liquid biopsies are paving the way for a new era of cancer screening. Detecting tumor-derived analytes in body fluids, these non-invasive tests could provide early diagnosis for everyone! #LiquidBiopsy #CancerScreening #EarlyDetection #PrecisionOncology t.co/z60uD5OzmV

Thanks for reposting!

CNS and immune system are deeply connected! Continuous crosstalk regulates #homeostasis and #neuroinflammation. Disruptions can drive #neurodegeneration, impacting cognitive function. Key areas: #gutbrainaxis #bloodbrainbarrier #circadianrhythms #Neuroscience #Immunology #Alzheimers t.co/LGun6OuCjX