Ashlan J. Kunz Coyne

I'm thrilled to share our lab's new manuscript on molecular and pharmacodynamic insights into beta-lactam therapy for E. cloacae high inoculum infections!
journals.asm.org/doi/10.1128/aa…

Special thanks to the team and to @sidpharm.bsky.social for the generous funding and supporting my vision.

That’s a very good buddy boy!

CDC/NHSN 2008: some of the changes since '08 may not have affected this specific study design, but I like the idea of evaluating that and incorporating pertinent changes moving forward.

I'm not convinced, but I certainly love the discussion around it :)

96 hours: extended from the usual 48-72h of continuous therapy. The decision was based on some previous data where steno PNA documented as colonization still received 72 h of therapy. An extra inclusion layer we tried. Could have missed some acute cases. It did align with our population.

Zero expectations for this one. I was brand new to the institution (and state) when I designed it, so dx and tx approaches were foreign to me. I do question whether (or how much) a concomitant bacteria (PA mostly) would've affected the cx/tx decisions for steno.

You bring up an excellent point. It's a necessary evaluation and I hope that someone does it! Consideration of non-infectious disease states as well.

Happy Friday! 🎉
A new episode just dropped: ESBL, UTIs & new antibiotics 💊🦠
What’s new? 🎙️ Link in comments.

#microbiology #podcast #ESBL #UTI #antibiotics

@ashlan-kunz-coyne.bsky.social

Propensity-Matched Comparison of Timely vs. Delayed Antibiotic Therapy in Stenotrophomonas maltophilia Pneumonia AbstractBackground. Stenotrophomonas maltophilia, a multidrug-resistant nosocomial pathogen, is associated with high mortality and therapeutic challenges d

This publication is different.

I began it 3 months postpartum, when my mind and body felt unfamiliar. Slowly, I found joy in writing again.

Seeing it published as an Editor’s Choice is deeply meaningful.

Grateful to the Kunz Coyne Lab for their support!

academic.oup.com/ofid/article...

Attending ASM Microbe? SIDP and ACCP ID PRN are co-hosting an ID Pharmacists and Friends Get Together! All pharmacists, friends, and trainees welcome!

When: Saturday, June 21st, 2025
Where: Lazy Dog
(Attendees will be responsible for own food/beverage)

Come join us! 🍻