@mikelhaggadone.bsky.social
NHLBI NRSA postdoc in the Sunny Shin Lab @ UPenn | PennFERBS mentor fellow | metabolism, innate immunity, cell death & inclusive education/mentorship | amino acid enthusiast | sometimes runs very far πββοΈ
This weekβs neighborhood scientist is Charity Robbins! Check out the link below to read Charityβs rules on how to build the perfect scientist (yes, really!!) neighborhoodscientist.org/posts/2025/l...
24.09.2025 14:52 β π 3 π 4 π¬ 1 π 0
π₯ #ImmunometabolismPower! Excited to have this officially out @cp-immunity.bsky.social π₯ We show that pathogens induce the host to produce oxidized lipids which rewire the #metabolism of #macrophages, causing #epigenetic modifications which dampen anti-inflammatory IL-10, exacerbating #inflammation!
10.09.2025 14:48 β π 83 π 18 π¬ 6 π 2
If you want to support the work we do, you can donate to my nonprofit @your.neighborhoodscientist.org here: neighborhoodscientist.org
10.09.2025 14:16 β π 2 π 3 π¬ 0 π 0Excited to be featured in todayβs @nature.com article about scientists standing up to Trump. Iβve never been one to sit on the sidelines, especially when something I believe so deeply inβscience funding that saves livesβis under attack. Read more here: www.nature.com/articles/d41...
10.09.2025 14:15 β π 23 π 10 π¬ 2 π 0Very stoked for and proud of my dear grad school pal, @jazib.bsky.social. No one pushes themselves harder than this guy! πͺ
A beautiful body of work!
Very excited to share the latest work from the Artis lab! Now out in @natimmunol.nature.com
Your gutβs neurons arenβt just for digestion; they help heal it too!
nature.com/articles/s41...
And huge congrats to my awesome mentor, @sunnyshinlab.bsky.social, for receiving the Faculty Mentorship Award. π No one is more deserving, and Iβm so thankful to follow your example!
07.08.2025 23:25 β π 3 π 0 π¬ 1 π 0
Iβm very honored to receive the inaugural Penn Postdoctoral Association Mentorship Award for my work with the Class of 2027 PennFERBS undergraduate scholars.
My students mean the absolute world and continue to amaze me with their drive, passion, and eagerness to grow as leaders in STEM. π
π¨ AAI is proud to announce the launch of the AAI RESTORE Grants Program, an $8M emergency funding initiative to support scientists whose immunology-focused federal research grants were abruptly terminated or frozen in 2025.
π ow.ly/rwMU50Wy3Mp
#AAIRESTORE
π£The @aai.org allocated $8M RESTORE Grants Program, an initiative that will focus on providing financial support to researchers whose grants were abruptly terminated or frozen in 2025 for reasons unrelated to their scientific merit! π
Check the details π
#SupportResearch
#Immunology
Macrophages kind of look like gastly (the PokΓ©mon)
Macrophage photo credit: Cell Wiki
Excellent! Preprintβs going up soon so perfect time to present!
21.07.2025 23:10 β π 2 π 0 π¬ 1 π 0Hope yβall consider PA to be in the Midwest!
21.07.2025 22:41 β π 2 π 0 π¬ 1 π 0
1/ If you are in the Midwest and β€οΈ metabolism, take note!
This yearβs Midwest Metabolism meeting will be held jointly with the Translational Research in Mitochondrial Metabolism in Aging and Disease (TRiMAD) conference.
www.vai.org/event/2025-m...
Regulation of inflammatory responses by pH-dependent transcriptional condensates @cellcellpress.bsky.social @xuzhoulab.bsky.social @rmedzhitov.bsky.social
www.cell.com/cell/fulltex...
#EpigeneticPower! π₯ #NewPaperAlert! We show @cp-immunity.bsky.social that endogenous oxidized lipids decide whether host survives or dies during #sepsis, #ARDS, or Staph infection! Ox lipids bind & inhibit #AKT, boosting inhibitory H3K27 methylation via EZH2 & blocking #IL10!
17.07.2025 15:35 β π 55 π 22 π¬ 6 π 2Honored to contribute a chapter with co-1st authors @mikelhaggadone.bsky.social, Brian Goldspiel & co-senior author @metabailism.bsky.social. Many thanks & congrats to co-editors @tristramryan.bsky.social, @lukeanthonyoneill.bsky.social, & Zbigniew Zaslona on an excellent immunometabolism resource!
11.07.2025 13:03 β π 13 π 2 π¬ 2 π 0Honored to contribute a chapter for this awesome immunometabolism resource!
10.07.2025 16:26 β π 6 π 2 π¬ 1 π 0
Are you interested in #immunometabolism but not sure where to start?
Introducing our new book βMetabolites as Signals in Immunity and Inflammationβ, co-edited with Zbigniew ZasΕona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
Super excited to share my final postdoc paper from Rabinowitz lab- on how whole-body and tissue metabolism changes in viral infection!
pubmed.ncbi.nlm.nih.gov/40581045/
Greetings from the Unites States of America, the world's largest funder of biomedical research! The background lists government agencies that fund biomedical research including NIH, NSF, USAID, DOE, DOD, NASA, EPA
Happy July 4th! Here at Your Neighborhood Scientist, weβre excited to highlight American patriotism in a way you might not always think about: scientific research.
neighborhoodscientist.org/posts/2025/j...
Weβre doing a July 4 feature all week highlighting how funding science is patriotic (and the incredible researchers doing life changing, tax payer funded research!) Give us a follow!
04.07.2025 16:01 β π 6 π 3 π¬ 0 π 0Share why doing and supporting science is patriotic at the poll below! πΊπΈ
27.06.2025 18:37 β π 6 π 4 π¬ 0 π 0
Structural basis of BAX pore formation @science.org
www.science.org/doi/10.1126/...
Excited to share that our paper examining how GM-CSF potentiates cytokine responses in human monocytes during bacterial infection is now online at the @asm.org journal Infection & Immunity! Congrats to @vvazquez.bsky.social, @mikelhaggadone.bsky.social, & co-authors! journals.asm.org/doi/full/10....
17.06.2025 12:50 β π 53 π 9 π¬ 3 π 0
I had SO much fun speaking about how amazing hearing is at Phillyβs @pintofscience.us last night!! Thank you to my amazing lab @geffenlab.bsky.social & @mikelhaggadone.bsky.social for coming out to support! π§ πΊ
22.05.2025 13:40 β π 10 π 2 π¬ 2 π 0
Pint of Science, Wed May 21st Two Locals Brewing, 7-9:30p
Philadelphia friends! We SO NEED to celebrate science. Let's raise a glass to brains.
Join us Wed, 5/21 for Pint of Science. I'll be opening for headliners Dimitris Boufidis, @audreydrotos.bsky.social, & Jacqui Barker. π
Tickets (to support the org, $2): pintofscience.us/events/phila...
I remember in 1989 when our basketball coach announced he was leaving after the NCAAs and was told βNope. Youβre out now.β Itβs time for Ono to be told that. Letβs have someone as interim who is reflecting Michigan values, fighting for us, and advocating for higher ed. We donβt need to wait.
08.05.2025 10:53 β π 11 π 4 π¬ 0 π 1
The best start to a week: Brian Goldspielβs phenomenal thesis defense today. For the last 5 years, itβs been a true joy getting to know the brilliant, multi-talented person Brian is. His infectious passion has transformed the lab and heβll be deeply missed. Could not be prouderπ₯²
06.05.2025 00:58 β π 27 π 4 π¬ 3 π 0Excited to be en route to Honolulu for the @aai.org Annual Meeting, #IMMUNOLOGY2025. Iβll be giving a talk tomorrow morning (Sunday) at 7 am in room 312. Come hear more about my postdoctoral research at the intersection of environmental nutrient sensing and regulation of the NLRP3 inflammasome.
03.05.2025 21:03 β π 3 π 1 π¬ 0 π 0
