Rylie Walsh

Comic: Common Sailing Rigs. [18 boats with different sail types, labeled.] Lateen; Bermuda rigged sloop; Ketch, Gaff rigged sloop; yawl; schooner; Ketch-rigged Gaff; Kloop-rigged sketch; bunkbed rig; Flettner rig; Oops, all Spinnakers; keel rig; kite rig; longsail rig; deckhand obliterator; offset rig; mastless rig; unclassifiable chaos rig.

Sailing Rigs

xkcd.com/3193/

Happy #MicroscopyMonday! 🧫 This week we're spotlighting Andy Stone, our immediate past-president at #NESM. 👏 @andystoneimaging.bsky.social

Andy leads the Brandeis light microscopy core and is a powerhouse in the imaging community—from BINA to NESM and RMS. 🎥🔬

#LightSheet #BioImaging #STEM

We are hiring!

Interested? Apply here: go.mbl.edu/AS1887

Do you like building novel optical microscopes to answer complex biological questions? How about doing that as part of one of the world’s most unique and vibrant research and education communities, which is incidentally located in a beautiful seaside New England village? 🐙🌊🔬

StayRose: a photostable StayGold derivative red-shifted by genetic code expansion Photobleaching of fluorescent proteins often limits the acquisition of high-quality images in microscopy. StayGold, a novel dimeric green fluorescent protein recently monomerised through sequence engi...

mStayRose is published in JBC 🥳🎉

Congratulations @wsctt.bsky.social @sporemohan.bsky.social and team for the monumental effort to make a non-natural amino acid incorporating fluorescent protein accessible. It's based on mStayGold, bright, and photostable:

www.jbc.org/article/S002...

A flyer for the Bioimage Analysis Beginnings Bootcamp - blue and white with a picture of cells on the top. It says "Learn core bioimage analysis skills using open-source tools for light microscopy. Open to participants at all skill levels." It also says it will be held a the Broad Institute, 415 Main Street, Cambridge MA USA, on Monday to Friday January 12th-16, 2026, from 9-5pm. Registration is $750 academic, $1250 industry, and applications are open at broad.io/BAB3

Big news! Our week-long #bioimageanalysis bootcamp is BACK! Learn how to think about bioimage analysis like the pros do, learn what corrections you should (and shouldn't!) apply to your images, learn open source tools, and more. Apply NOW at broad.io/BAB3 for our January 2026 course!

Everyone who does quantitative microscopy should read this! It’s amazing how many ways we can bias our imaging experiments without realizing we’re doing it.

Announcing registration for the Fall Symposium at Brandeis for #MicroscopyMonday! #NESM
www.nesmicroscopy.org/2025-fall-sy...

🔬: Bruker TruLive3D @brukerspatial.bsky.social
🥼: Amro Hamdoun @hamdounlab.bsky.social ‬, Tzer Han Tan's @tzerhan29.bsky.social group
🌌: Painted Sea Urchin
📷: syGlass.io

Focus In: MBL Expands Training in Advanced Microscopy | Marine Biological Laboratory

The deadline to register for MBL's fall course, Light Microscopy Bootcamp, is this Friday, August 15!🔬

The course is engineered to empower graduate students to use light microscopy in their own research.

Read more: bit.ly/4e5QA0y

📷 Mark Lessard

Black and white scanning electron micrograph of a Lily of the Valley flower showing three anthers, each with a textured, folded surface. The anthers are suspended above a cellular platform-like base, revealing intricate tissue structure and fine surface detail at high magnification.

Announcing our first Fall Symposium speaker for #MicroscopyMonday! Geoff Williams, Brown. #NESM

🌾: Lily of the Valley
🥼: Geoff Williams, @gewilli.bsky.social
🏛️: @brownuresearch.bsky.social Leduc Bioimaging Facility
🔬: @thermofishersci.bsky.social Apreo 2 VS Scanning Electron Microscope, HFW 4mm

Membership is free this year! Join us to be part of a friendly, engaged and long-standing community of local microscopists. All backgrounds and career stages from academia and industry are welcome!

Me except I do this on a normal workday, when I just saw my cat 4 hours ago and will see him again in another 4 hours.

I still can’t believe that all NIH grants to my colleagues at Harvard and Harvard Medical School have been nullified. And that, as a nation, we’re somehow okay with this illegal, arbitrary, and petty act. Just think of the consequences: scientists, students, and patients will all suffer.

Here Is All the Science at Risk in Trump’s Clash With Harvard (Gift Article) More than 900 research grants worth $2.6 billion are in jeopardy. So is the 80-year-old model of American science.

"The money the government sends to Harvard is, in effect, not a subsidy to advance the university’s mission. It’s a payment for the role Harvard plays in advancing the research mission of the United States." www.nytimes.com/interactive/...

Whoa, the mCherry signal on that microorganism is fantastic! 😂

I'm a current Harvard graduate student and I found out today that I had my NSF GRFP terminated without notification. I was awarded this individual research fellowship before even choosing Harvard as my graduate school

2025 Grass Fellows: Zeeshan Banday - University of Chicago Mechanoelectrical transduction in jellyfish Sam Chakrabarti - Max Delbruck Center Pain sensation in sharks Alex Chen - Harvard University Ctenophore nerve net development David Hildebrand - The Rockefeller University Face recognition in paper wasps Chris Hoffmann - German Center for Neurodegenerative Diseases Ocean acidification and behavior in sea slugs Hannah Oberle - University of Michigan Synaptic plasticity in mouse inferior colliculus Kyra Schapiro - Brandeis University Molluscan shell patterning Alex Yarger - Imperial College London Dragonfly flight control

Looking for some good news today?

We have eight inspiring early-career scientists heading to @mblscience.bsky.social to spend the summer conducting research on topics ranging from pain sensation in sharks to ocean acidification and behavior in sea slugs.

grassfoundation.org/announcing-t...

Side-by-side TEM images and 3D reconstructions of lamprey synapses. Control shows dense synaptic vesicles and organized structure; high pS129 alpha-synuclein shows dispersed vesicles and disrupted architecture.

For #MicroscopyMonday: 3D reconstructions of lamprey reticulospinal synapses
🐉: Petromyzon marinus
🥼: Jaqulin Wallace, @mblscience.bsky.social
🔬: JEOL JEM-200CX, MBL’s Central Microscopy Facility
📄: doi.org/10.1091/mbc....

#Neurodegeneration #ElectronMicroscopy #MBL #Microscopy #Parkinsons #NESM

AI@MBL: Machine Learning for Microscopy Image Analysis | Marine Biological Laboratory The goal of this course is to familiarize researchers in the life sciences with state-of-the-art deep learning techniques for microscopy image analysis and to introduce them to tools and frameworks th...

How can AI help you to analyze your microscopy images?

Find out at the "Machine Learning for Microscopy Image Analysis" course at the @mblscience.bsky.social in Woods Hole from Aug 22-Sep 6!

Applications are due 🚨 April 30 🚨

Read on for more! 👇

www.mbl.edu/education/ad...

The Roads Both Taken xkcd.com/3076

Just over 24 hours until the abstract deadline for the @nesmicroscopy.bsky.social Spring Symposium which is taking place virtually on April 25th. shorturl.at/040Hh If you have a topic that our community would enjoy please submit an abstract! Shares appreciated!

Submit an abstract to be considered for a short talk at our Virtual Spring Symposium! Please also share to help us reach as many microscopists as possible! Membership is also free for 2025 #NESMicroscopy

Another wonderful @sciencedoodles.bsky.social creation!

YouTube video by Marine Biological Laboratory A cleared juvenile axolotl labeled for DAPI

#MicroscopyMonday 🔬 This axolotl, labeled for DAPI (a DNA stain) and Sox9 (a transcription factor), was imaged by
@ryliewalsh.bsky.social on the MBL's stage-scanning line confocal microscope.

Specimen: Prayag Murawala, Mount Desert Island Biological Laboratory

youtu.be/UPLPkKhcxHk

Come learn microscopy with us by the sea in May!

I have not seen a crisis of this magnitude since yesterday

Ask your doctor if running screaming into the savage night might be right for you.

Thanksgiving Luncheon @mblscience.bsky.social
I’m grateful to be part of the MBL’s wonderful year-round community! 🦃🦑