Javi Ibarrondo

Leaked document. Yikes, things are about to get much worse. It looks like we’re on the verge of becoming a military state across the country. Step out of line, and the man come and take you away.

IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity IL-25 treatment induces persistent adaptation of the small intestine, which is maintained by ILC2s with functional and epigenetic qualities of immune memory. Effector-memory ILC2s arise in multiple ti...

www.cell.com/cell/fulltex... 🧪

Spatial and functional diversity of innate lymphoid cells in the human female genital tract may contribute to antiviral responses to HIV - Nature Immunology The authors spatially and functionally map innate lymphoid cells in the human female genital tract at homeostasis, uncovering tissue-specific and subset-specific distribution and functions, and rapid ...

www.nature.com/articles/s41... 🧪

Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapy - Nature Immunology Klein and colleagues characterize 04_A06, a new VH1-2-encoded broadly neutralizing antibody that has marked breadth and potency against extended multiclade HIV-1 pseudovirus panels and can maintain fu...

www.nature.com/articles/s41... 🧪

Polygenic and developmental profiles of autism differ by age at diagnosis - Nature A study of several longitudinal birth cohorts and cross-sectional cohorts finds only moderate overlap in genetic variants between autism that is diagnosed earlier and that diagnosed later, so they may...

www.nature.com/articles/s41... 🧪

Age and gender distortion in online media and large language models - Nature Stereotypes of age-related gender bias are socially distorted, as evidenced by the age gap in the representations of women and men across various media and algorithms, despite no systematic age differ...

www.nature.com/articles/s41... 🧪

How scientists are pushing back against Trump’s funding ‘deal’ for universities Seven institutions have so far rejected the administration’s list of demands over academic freedom and other concerns.

www.nature.com/articles/d41... 🧪

Blood tests are now approved for Alzheimer’s: how accurate are they? A second blood test has been been approved by the US Food and Drug Administration to assist in diagnosing Alzheimer’s disease. Will these tests change how cognitive decline is measured?

www.nature.com/articles/d41... 🧪

What a lovely bunch 🤮

To thwart food poisoning, tiny needles could inject bacteria-slaying viruses into your meal Experimental patches on meat, fruits, and vegetables can destroy up to 99.9% of bacteria

To thwart food poisoning, tiny needles could inject bacteria-slaying viruses into your meal | Science | AAAS www.science.org/content/arti... 🧪

Meta and TikTok are obstructing researchers’ access to data, European Commission rules Data are needed to study how social media spreads misinformation and influences elections, scientists say

Meta and TikTok are obstructing researchers’ access to data, European Commission rules | Science | AAAS www.science.org/content/arti... 🧪

Aquarium hijinks provide strongest evidence yet that sharks love to play Study hints at a deeper intelligence—and a need for enrichment in captivity

Aquarium hijinks provide strongest evidence yet that sharks love to play | Science | AAAS www.science.org/content/arti... 🧪

Vaccine protects people from paratyphoid fever in a ‘human challenge’ study Volunteers who swallowed disease-causing bacteria were less likely to get sick after an oral vaccine

Vaccine protects people from paratyphoid fever in a ‘human challenge’ study | Science | AAAS www.science.org/content/arti... 🧪

Facing claims of animal abuse, a major breeder of research dogs will close its pipeline Ridglan Farms has agreed to stop selling beagles for scientific studies, leaving just one major U.S. supplier

Facing claims of animal abuse, a major breeder of research dogs will close its pipeline | Science | AAAS www.science.org/content/arti... 🧪

Targeting PTPN2 enhances human CAR T cell efficacy and the development of long-term memory in mouse xenograft models PTPN2 deletion or inhibition boosts CAR T cell function and promotes the formation of stem cell memory CAR T cells for persistent solid tumor control.

Targeting PTPN2 enhances human CAR T cell efficacy and the development of long-term memory in mouse xenograft models | Science Translational Medicine www.science.org/doi/10.1126/... 🧪

Single antivenom protects against 17 different snakebites Researchers immunized an alpaca and a llama with snake venoms, and combined some of the antibodies produced into a potent cocktail.

Researchers immunized an alpaca and a llama with snake venoms, and combined some of the antibodies produced into a potent cocktail

go.nature.com/47LQB8d

AI hallucinates because it’s trained to fake answers it doesn’t know Teaching chatbots to say “I don’t know” could curb hallucinations. It could also break AI’s business model

AI hallucinates because it’s trained to fake answers it doesn’t know | Science | AAAS www.science.org/content/arti... 🧪

Louisiana officials waited months to warn public of whooping cough outbreak After a whooping cough outbreak killed two infants, Louisiana health officials waited months to officially alert physicians or do public outreach. That's not the typical public health response.

The thing about outbreaks of infectious diseases is that you can only hide them for so long. Time literally is containment.
And the whistle always blows once people start to die ( in this instance babies). This is why we have public health surveillance and reporting.
www.npr.org/sections/sho...

Therapeutic IgG- and IgM-specific proteases disarm the acetylcholine receptor autoantibodies that drive myasthenia gravis pathology | PNAS www.pnas.org/doi/10.1073/... 🧪

The genetic lottery goes to school: Better schools compensate for the effects of students’ genetic differences | PNAS www.pnas.org/doi/10.1073/... 🧪

A national randomized controlled trial of the impact of public Montessori preschool at the end of kindergarten | PNAS Although seminal studies from the early 1960s suggested quality preschool can have lasting positive effects, agreement is lacking on the efficacy o...

A national randomized controlled trial of the impact of public Montessori preschool at the end of kindergarten | PNAS www.pnas.org/doi/10.1073/... 🧪

Smartphone use in a large US adult population: Temporal associations between objective measures of usage and mental well-being | PNAS www.pnas.org/doi/10.1073/... 🧪

Man’s pig kidney fails just shy of setting record The xenotransplant, from a gene-edited pig, had survived for nearly 9 months in Tim Andrews

Man’s pig kidney fails just shy of setting record | Science | AAAS www.science.org/content/arti... 🧪

Congress close to passing law that would freeze out certain Chinese biotechs Latest version of Biosecure Act could raise costs for academic biology labs in an effort to prevent theft of Americans’ health data

Congress close to passing law that would freeze out certain Chinese biotechs | Science | AAAS www.science.org/content/arti... 🧪

Argentina’s move to woo Trump has derailed South America’s largest radio telescope U.S.-Chinese tensions have left nearly complete observatory in limbo, jeopardizing research into pulsars and other celestial objects

Argentina’s move to woo Trump has derailed South America’s largest radio telescope | Science | AAAS www.science.org/content/arti... 🧪

How NSF hopes to keep Antarctic scientists afloat without an icebreaker Ending Palmer lease is one of many belt-tightening moves amid budget uncertainty

How NSF hopes to keep Antarctic scientists afloat without an icebreaker | Science | AAAS www.science.org/content/arti... 🧪

Rats filmed snatching bats from air for first time Stunning hunting behaviour captured in German cave

Rats filmed snatching bats from air for first time | Science | AAAS www.science.org/content/arti... 🧪

Fat-chomping enzyme that ‘moonlights’ as gene regulator could point to obesity treatments Hormone-sensitive lipase works in the nucleus to keep fat cells healthy, new study suggests

Fat-chomping enzyme that ‘moonlights’ as gene regulator could point to obesity treatments | Science | AAAS www.science.org/content/arti... 🧪

University of California faculty push back against Big Brother cybersecurity mandate School officials defend software as bulwark against ransomware, but professors fear potential surveillance of their devices

University of California faculty push back against Big Brother cybersecurity mandate | Science | AAAS www.science.org/content/arti... 🧪

Can the Deadliest Catch crab fishery survive warming seas? After a brutal heat wave, scientists race to predict how Bering Sea snow crabs will cope with climate change

Can the Deadliest Catch crab fishery survive warming seas? | Science | AAAS www.science.org/content/arti... 🧪